Regulation of hepatic lipin-1 by ethanol: role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice - Wikidata - awgldk - TriplyDB

Regulation of hepatic lipin-1 by ethanol: role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice

Regulation of hepatic lipin-1 by ethanol: role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice

http://www.wikidata.org/entity/Q35659167

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Role of Transcription Factors in Steatohepatitis and Hypertension after Ethanol: The Epicenter of Metabolism Mechanisms of intrahepatic triglyceride accumulation Role of microRNAs in Alcohol-Induced Multi-Organ Injury Liver steatosis in hepatitis C patients New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases Epigenetic Modifications, Alcoholic Brain and Potential Drug Targets miR-217 regulates ethanol-induced hepatic inflammation by disrupting sirtuin 1-lipin-1 signaling.MicroRNA-217 promotes ethanol-induced fat accumulation in hepatocytes by down-regulating SIRT1.Novel Akt activator SC-79 is a potential treatment for alcohol-induced osteonecrosis of the femoral head Autophagy in alcohol-induced multiorgan injury: mechanisms and potential therapeutic targets Counteracting roles of AMP deaminase and AMP kinase in the development of fatty liver Pathogenesis of alcoholic liver disease: role of oxidative metabolism.Liver-specific loss of lipin-1-mediated phosphatidic acid phosphatase activity does not mitigate intrahepatic TG accumulation in mice Sirtuin 1 signaling and alcoholic fatty liver disease.Herbal SGR Formula Prevents Acute Ethanol-Induced Liver Steatosis via Inhibition of Lipogenesis and Enhancement Fatty Acid Oxidation in Mice Sustained antidiabetic effects of a berberine-containing Chinese herbal medicine through regulation of hepatic gene expression.Ethanol administration exacerbates the abnormalities in hepatic lipid oxidation in genetically obese mice.Liver MicroRNA-291b-3p Promotes Hepatic Lipogenesis through Negative Regulation of Adenosine 5'-Monophosphate (AMP)-activated Protein Kinase α1.Signal Transduction Mechanisms of Alcoholic Fatty Liver Disease: Emerging Role of Lipin-1.Ethanol metabolism and oxidative stress are required for unfolded protein response activation and steatosis in zebrafish with alcoholic liver disease.Mouse model of chronic and binge ethanol feeding (the NIAAA model)Myeloid Cell-Specific Lipin-1 Deficiency Stimulates Endocrine Adiponectin-FGF15 Axis and Ameliorates Ethanol-Induced Liver Injury in Mice.Hepatic-specific lipin-1 deficiency exacerbates experimental alcohol-induced steatohepatitis in mice.Deletion of SIRT1 from hepatocytes in mice disrupts lipin-1 signaling and aggravates alcoholic fatty liver.The role of lipin-1 in the pathogenesis of alcoholic fatty liver.Liver-specific Gene Inactivation of the Transcription Factor ATF4 Alleviates Alcoholic Liver Steatosis in Mice.Roles of silent information regulator 1-serine/arginine-rich splicing factor 10-lipin 1 axis in the pathogenesis of alcohol fatty liver disease.How lipid droplets "TAG" along: Glycerolipid synthetic enzymes and lipid storage.The Role of Lipin-1 in the Regulation of Fibrogenesis and TGF-β Signaling in Hepatic Stellate Cells.The Detrimental Role Played by Lipocalin-2 in Alcoholic Fatty Liver in Mice.Induction of Lipin1 by ROS-Dependent SREBP-2 Activation.The adiponectin-SIRT1-AMPK pathway in alcoholic fatty liver disease in the rat.Ethanol-triggered Lipophagy Requires SQSTM1 in AML12 Hepatic Cells.Lipin1-Mediated Repression of Adipogenesis by Rutin.Carnosic acid alleviates chronic alcoholic liver injury by regulating the SIRT1/ChREBP and SIRT1/p66shc pathways in rats.Alcohol and Hepatocellular Carcinoma: Adding Fuel to the Flame.Acanthoic acid suppresses lipin1/2 via TLR4 and IRAK4 signalling pathways in EtOH- and lipopolysaccharide-induced hepatic lipogenesis.LKB1/AMPK-Mediated Regulation by Gentiopicroside Ameliorates P2x7R-Dependent Alcoholic Hepatosteatosis.DEPTOR Suppresses Lipogenesis and Ameliorates Hepatic Steatosis and Acute-on-Chronic Liver Injury in Alcoholic Liver Disease.Resveratrol ameliorates lipid accumulation in HepG2 cells, associated with down-regulation of lipin1 expression.

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Regulation of hepatic lipin-1 by ethanol: role of AMP-activated protein kinase/sterol regulatory element-binding protein 1 signaling in mice

http://www.wikidata.org/entity/Q35659167

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Regulation of hepatic lipin-1 ...... ng protein 1 signaling in mice

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Regulation of hepatic lipin-1 ...... ng protein 1 signaling in mice

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Brian N Finck

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Christopher Q Rogers

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Dave A Mitchell

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Fengming Wang

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Mayurranjan S Mitra

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Min You

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Ming Hu

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Ray Zhang

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Xiaomei Liang

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Xin Li

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P2860

Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin

Differential expression of exons 1a and 1c in mRNAs for sterol regulatory element binding protein-1 in human and mouse organs and cultured cells

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

An acetylation/deacetylation-SUMOylation switch through a phylogenetically conserved psiKXEP motif in the tumor suppressor HIC1 regulates transcriptional repression activity

Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway

Ethanol induces fatty acid synthesis pathways by activation of sterol regulatory element-binding protein (SREBP)

Sumoylation regulates nuclear localization of lipin-1alpha in neuronal cells.

AMPK phosphorylates and inhibits SREBP activity to attenuate hepatic steatosis and atherosclerosis in diet-induced insulin-resistant mice

mTOR complex 1 regulates lipin 1 localization to control the SREBP pathway.

Dual function lipin proteins and glycerolipid metabolism

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437-446

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10.1002/HEP.24708

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2

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21953514

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3253249

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