A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis - Wikidata - awgldk - TriplyDB

A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis

A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis

http://www.wikidata.org/entity/Q35665048

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Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targeting A fresh look at zebrafish from the perspective of cancer research Sequencing Overview of Ewing Sarcoma: A Journey across Genomic, Epigenomic and Transcriptomic Landscapes Hooking the big one: the potential of zebrafish xenotransplantation to reform cancer drug screening in the genomic era Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model Zebrafish cancer: the state of the art and the path forward.Loss of function tp53 mutations do not accelerate the onset of myc-induced T-cell acute lymphoblastic leukaemia in the zebrafish Mosaic zebrafish transgenesis for functional genomic analysis of candidate cooperative genes in tumor pathogenesis.Englerin A Inhibits EWS-FLI1 DNA Binding in Ewing Sarcoma Cells Loss of Ewing sarcoma EWS allele promotes tumorigenesis by inducing chromosomal instability in zebrafish.The adolescent and young adult with cancer: state of the art -- bone tumors.Optimal management of Ewing sarcoma family of tumors: recent developments in systemic therapy.Zebrafish models of cancer: progress and future challenges Blocking the road, stopping the engine or killing the driver? Advances in targeting EWS/FLI-1 fusion in Ewing sarcoma as novel therapy.The promise of zebrafish as a chemical screening tool in cancer therapy.Wnt Signaling in Ewing Sarcoma, Osteosarcoma, and Malignant Peripheral Nerve Sheath Tumors.Modeling the initiation of Ewing sarcoma tumorigenesis in differentiating human embryonic stem cells.EWS/FLI utilizes NKX2-2 to repress mesenchymal features of Ewing sarcoma.Optical Control of Tumor Induction in the Zebrafish Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformation.Zebrafish models for human cancer.Zebrafish as a Model for the Study of Solid Malignancies.IRE1α-XBP1 inhibitors exerted anti-tumor activities in Ewing's sarcoma.PAX3-FOXO1 transgenic zebrafish models identify HES3 as a mediator of rhabdomyosarcoma tumorigenesis.How Surrogate and Chemical Genetics in Model Organisms Can Suggest Therapies for Human Genetic Diseases.

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A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis

http://www.wikidata.org/entity/Q35665048

description

2011 nî lūn-bûn

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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2011年论文

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name

A zebrafish transgenic model o ...... tors of EWS-FLI1 tumorigenesis

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A zebrafish transgenic model o ...... tors of EWS-FLI1 tumorigenesis

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type

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A zebrafish transgenic model o ...... tors of EWS-FLI1 tumorigenesis

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A zebrafish transgenic model o ...... tors of EWS-FLI1 tumorigenesis

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A zebrafish transgenic model o ...... tors of EWS-FLI1 tumorigenesis

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A zebrafish transgenic model o ...... tors of EWS-FLI1 tumorigenesis

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A zebrafish transgenic model o ...... tors of EWS-FLI1 tumorigenesis

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Anne M Kirk

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Audrey N Basse

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Dinesh Rakheja

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Garvin L Chandler

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James F Amatruda

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Stefanie W Leacock

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P2860

EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma

Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles.

A molecular map of mesenchymal tumors.

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

Identification of the transforming EML4-ALK fusion gene in non-small-cell lung cancer.

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma

An RNA-binding protein gene, TLS/FUS, is fused to ERG in human myeloid leukemia with t(16;21) chromosomal translocation

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95-106

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10.1242/DMM.007401

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1

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21979944

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