Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.
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Stem cell-based regenerative opportunities for the liver: State of the art and beyondTwo Effective Routes for Removing Lineage Restriction Roadblocks: From Somatic Cells to HepatocytesParametric analysis of colony morphology of non-labelled live human pluripotent stem cells for cell quality control.Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineeringCholesterol-secreting and statin-responsive hepatocytes from human ES and iPS cells to model hepatic involvement in cardiovascular healthHistone deacetylase inhibitor valproic acid promotes the differentiation of human induced pluripotent stem cells into hepatocyte-like cellsStem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injuryMolecular mechanisms underlying the enhanced functions of three-dimensional hepatocyte aggregatesA sequential EMT-MET mechanism drives the differentiation of human embryonic stem cells towards hepatocytes.Aggregate culture of human embryonic stem cell-derived hepatocytes in suspension are an improved in vitro model for drug metabolism and toxicity testing.Induction of highly functional hepatocytes from human umbilical cord mesenchymal stem cells by HNF4α transductionPrediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes.Dual gene expression in embryoid bodies derived from human induced pluripotent stem cells using episomal vectors.Integration-deficient lentivectors: an effective strategy to purify and differentiate human embryonic stem cell-derived hepatic progenitors.HHEX promotes hepatic-lineage specification through the negative regulation of eomesodermin.Human iPSC-derived hepatocyte-like cells support Plasmodium liver-stage infection in vitro.Potential and Challenges of Induced Pluripotent Stem Cells in Liver Diseases Treatment.Improved Survival and Initiation of Differentiation of Human Induced Pluripotent Stem Cells to Hepatocyte-Like Cells upon Culture in William's E Medium followed by Hepatocyte Differentiation Inducer Treatment.New Tools in Experimental Cellular Therapy for the Treatment of Liver Diseases.Mesenchymal stem cell-derived hepatocytes for functional liver replacement.Hepatocyte selection medium eliminating induced pluripotent stem cells among primary human hepatocytes.Rapid and high-efficiency generation of mature functional hepatocyte-like cells from adipose-derived stem cells by a three-step protocolDonor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells.Generation of enterocyte-like cells from human induced pluripotent stem cells for drug absorption and metabolism studies in human small intestineWind of change challenges toxicological regulators.Stochastic model-assisted development of efficient low-dose viral transduction in microfluidicsHepatocyte-like cells differentiated from human induced pluripotent stem cells: relevance to cellular therapies.New frontier in regenerative medicine: site-specific gene correction in patient-specific induced pluripotent stem cellsCell sources for in vitro human liver cell culture models.Scalable Differentiation of Human iPSCs in a Multicellular Spheroid-based 3D Culture into Hepatocyte-like Cells through Direct Wnt/β-catenin Pathway Inhibition.Sustained Delivery Growth Factors with Polyethyleneimine-Modified Nanoparticles Promote Embryonic Stem Cells Differentiation and Liver Regeneration.Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes.Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells.Physiological ranges of matrix rigidity modulate primary mouse hepatocyte function in part through hepatocyte nuclear factor 4 alpha.Single-step protocol for the differentiation of human-induced pluripotent stem cells into hepatic progenitor-like cells.A single transcription factor is sufficient to induce and maintain secretory cell architectureHuman induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection.Stem cell and biomaterials research in dental tissue engineering and regenerationStem cell therapy: an exercise in patience and prudence.The future of the patient-specific Body-on-a-chip.
P2860
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P2860
Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Efficient generation of functi ...... m cells by HNF4α transduction.
@ast
Efficient generation of functi ...... m cells by HNF4α transduction.
@en
type
label
Efficient generation of functi ...... m cells by HNF4α transduction.
@ast
Efficient generation of functi ...... m cells by HNF4α transduction.
@en
prefLabel
Efficient generation of functi ...... m cells by HNF4α transduction.
@ast
Efficient generation of functi ...... m cells by HNF4α transduction.
@en
P2093
P2860
P356
P1433
P1476
Efficient generation of functi ...... em cells by HNF4α transduction
@en
P2093
Aki Nonaka
Fuminori Sakurai
Hiroyuki Mizuguchi
Katsuhisa Tashiro
Kazufumi Katayama
Kenji Kawabata
Maiko Higuchi
Mitsuru Inamura
Takao Hayakawa
P2860
P304
P356
10.1038/MT.2011.234
P577
2011-11-08T00:00:00Z