Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes. - Wikidata - awgldk - TriplyDB

Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes.

Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes.

http://www.wikidata.org/entity/Q34601581

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Value of monitoring Nrf2 activity for the detection of chemical and oxidative stress Stem cell-derived liver cells for drug testing and disease modeling Pluripotent stem cell derived hepatocytes: using materials to define cellular differentiation and tissue engineering Differences in the Epigenetic Regulation of Cytochrome P450 Genes between Human Embryonic Stem Cell-Derived Hepatocytes and Primary Hepatocytes Stem cell-derived models to improve mechanistic understanding and prediction of human drug-induced liver injury Patient-specific hepatocyte-like cells derived from induced pluripotent stem cells model pazopanib-mediated hepatotoxicity Donor-Dependent and Other Nondefined Factors Have Greater Influence on the Hepatic Phenotype Than the Starting Cell Type in Induced Pluripotent Stem Cell Derived Hepatocyte-Like Cells.The Promise and Challenge of Induced Pluripotent Stem Cells for Cardiovascular Applications.Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells.CPM Is a Useful Cell Surface Marker to Isolate Expandable Bi-Potential Liver Progenitor Cells Derived from Human iPS Cells.Generation of enterocyte-like cells from human induced pluripotent stem cells for drug absorption and metabolism studies in human small intestine Xeno-sensing activity of the aryl hydrocarbon receptor in human pluripotent stem cell-derived hepatocyte-like cells.Minireview: Genome Editing of Human Pluripotent Stem Cells for Modeling Metabolic Disease.Asialoglycoprotein receptor 1 is a specific cell-surface marker for isolating hepatocytes derived from human pluripotent stem cells.Cell sources for in vitro human liver cell culture models.Prediction of Differentiation Tendency Toward Hepatocytes from Gene Expression in Undifferentiated Human Pluripotent Stem Cells.Generation of a bile salt export pump deficiency model using patient-specific induced pluripotent stem cell-derived hepatocyte-like cells Human induced-pluripotent stem cell-derived hepatocyte-like cells as an in vitro model of human hepatitis B virus infection.Concise Review: Patient-Derived Stem Cell Research for Monogenic Disorders.Opportunities and challenges in using human hepatocytes in cytochromes P450 induction assays.Metabolic activation and drug-induced liver injury: in vitro approaches for the safety risk assessment of new drugs.A new era of disease modeling and drug discovery using induced pluripotent stem cells.Concise Review: Advances in Generating Hepatocytes from Pluripotent Stem Cells for Translational Medicine.Emerging In Vitro Liver Technologies for Drug Metabolism and Inter-Organ Interactions.Concise Review: Liver Regenerative Medicine: From Hepatocyte Transplantation to Bioartificial Livers and Bioengineered Grafts.One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells.Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease.Hepatic Differentiation of Human Induced Pluripotent Stem Cells in a Perfused Three-Dimensional Multicompartment Bioreactor.Footprint-free human fetal foreskin derived iPSCs: A tool for modeling hepatogenesis associated gene regulatory networks.Laminin-guided highly efficient endothelial commitment from human pluripotent stem cells.Sensitive and long-term monitoring of intracellular microRNAs using a non-integrating cytoplasmic RNA vector.Prediction of cytochrome P450-mediated drug clearance in humans based on the measured activities of selected CYPs.Direct conversion of human fibroblasts into hepatocyte-like cells by ATF5, PROX1, FOXA2, FOXA3, and HNF4A transduction.Pluripotent Stem Cell-Derived Human Tissue: Platforms to Evaluate Drug Metabolism and Safety.Paracrine signals regulate human liver organoid maturation from induced pluripotent stem cells.Human ESC/iPSC-Derived Hepatocyte-like Cells Achieve Zone-Specific Hepatic Properties by Modulation of WNT Signaling.Stem Cell Therapies for Treatment of Liver Disease.Hepatocyte Nuclear Factor 4 Alpha Promotes Definitive Endoderm Differentiation from Human Induced Pluripotent Stem Cells.Chemically induced hepatotoxicity in human stem cell-induced hepatocytes compared with primary hepatocytes and HepG2.

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P2860

Prediction of interindividual differences in hepatic functions and drug sensitivity by using human iPS-derived hepatocytes.

http://www.wikidata.org/entity/Q34601581

description

2014 nî lūn-bûn

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2014 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2014 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Prediction of interindividual ...... human iPS-derived hepatocytes.

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Prediction of interindividual ...... human iPS-derived hepatocytes.

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Prediction of interindividual ...... human iPS-derived hepatocytes.

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Prediction of interindividual ...... human iPS-derived hepatocytes.

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Proceedings of the National Academy of Sciences of the United States of America

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Prediction of interindividual ...... human iPS-derived hepatocytes

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Emiko Noguchi

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Fuminori Sakurai

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Hiroyuki Mizuguchi

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Kazumasa Hirata

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Kazuo Harada

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Kazuo Imagawa

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Ken Nishimura

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Kenji Kawabata

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Manami Ohtaka

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Norihisa Furukawa

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P2860

Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells

Pharmacogenetics of cytochrome P450 and its applications in drug therapy: the past, present and future.

Genetic susceptibility to adverse effects of drugs and environmental toxicants. The role of the CYP family of enzymes.

Development of defective and persistent Sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming

A chemical platform for improved induction of human iPSCs.

Efficient generation of functional hepatocytes from human embryonic stem cells and induced pluripotent stem cells by HNF4α transduction.

Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity.

Long-term self-renewal of human ES/iPS-derived hepatoblast-like cells on human laminin 111-coated dishes.

Polymorphism of human cytochrome P450 2D6 and its clinical significance: Part I.

Developing high-fidelity hepatotoxicity models from pluripotent stem cells

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