Hepatic Atypical Protein Kinase C: An Inherited Survival-Longevity Gene that Now Fuels Insulin-Resistant Syndromes of Obesity, the Metabolic Syndrome and Type 2 Diabetes Mellitus

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Modulation of Insulin Sensitivity of Hepatocytes by the Pharmacological Downregulation of Phospholipase D.Conditional knockout of polarity complex (atypical) PKCι reveals an anti-inflammatory function mediated by NF-κB.

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Hepatic Atypical Protein Kinase C: An Inherited Survival-Longevity Gene that Now Fuels Insulin-Resistant Syndromes of Obesity, the Metabolic Syndrome and Type 2 Diabetes Mellitus

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http://www.wikidata.org/entity/Q35667136

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2014 nî lūn-bûn

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2014年の論文

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2014年論文

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2014年論文

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2014年論文

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2014年論文

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2014年论文

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Hepatic Atypical Protein Kinas ...... e and Type 2 Diabetes Mellitus

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Hepatic Atypical Protein Kinas ...... e and Type 2 Diabetes Mellitus

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Hepatic Atypical Protein Kinas ...... e and Type 2 Diabetes Mellitus

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Hepatic Atypical Protein Kinas ...... e and Type 2 Diabetes Mellitus

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Hepatic Atypical Protein Kinas ...... e and Type 2 Diabetes Mellitus

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Hepatic Atypical Protein Kinas ...... e and Type 2 Diabetes Mellitus

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Hepatic Atypical Protein Kinas ...... e and Type 2 Diabetes Mellitus

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Mackenzie C Lee

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Mini P Sajan

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Robert V Farese

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P2860

Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes

Role of AMP-activated protein kinase in mechanism of metformin action

A WD-FYVE protein binds to the kinases Akt and PKCzeta/lambda

Akt- and Foxo1-interacting WD-repeat-FYVE protein promotes adipogenesis

PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

Central role of ceramide biosynthesis in body weight regulation, energy metabolism, and the metabolic syndrome

Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells

Role of atypical protein kinase C in activation of sterol regulatory element binding protein-1c and nuclear factor kappa B (NFkappaB) in liver of rodents used as a model of diabetes, and relationships to hyperlipidaemia and insulin resistance

PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity

Bifurcation of insulin signaling pathway in rat liver: mTORC1 required for stimulation of lipogenesis, but not inhibition of gluconeogenesis

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724-740

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scholarly article

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10.3390/JCM3030724

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2014-07-07T00:00:00Z

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265722664

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26237474

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Adipositas

type-2 diabetes

metabolic syndrome

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4449650

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Hepatic Atypical Protein Kinase C: An Inherited Survival-Longevity Gene that Now Fuels Insulin-Resistant Syndromes of Obesity, the Metabolic Syndrome and Type 2 Diabetes Mellitus

about

P2860

P2860

Hepatic Atypical Protein Kinase C: An Inherited Survival-Longevity Gene that Now Fuels Insulin-Resistant Syndromes of Obesity, the Metabolic Syndrome and Type 2 Diabetes Mellitus

description

name

type

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P1433

P1476

P2093

P2860

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P356

P433

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P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P5875

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P932