Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells - Wikidata - awgldk - TriplyDB

Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells

Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells

http://www.wikidata.org/entity/Q28251494

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A ceramide-binding C1 domain mediates kinase suppressor of ras membrane translocation Roles of bioactive sphingolipids in cancer biology and therapeutics Analysis of membrane topology of neutral sphingomyelinase 2 A review of ceramide analogs as potential anticancer agents Alterations of the Ceramide Metabolism in the Peri-Infarct Cortex Are Independent of the Sphingomyelinase Pathway and Not Influenced by the Acid Sphingomyelinase Inhibitor Fluoxetine Par-4: a new activator of myosin phosphatase Protein kinase C isoforms: Multi-functional regulators of cell life and death Regulation of neural progenitor cell motility by ceramide and potential implications for mouse brain development Phospholipid and sphingolipid metabolism in Leishmania.Re-configuration of sphingolipid metabolism by oncogenic transformation.Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide.Altered expression of atypical PKC and Ryk in the spinal cord of a mouse model of amyotrophic lateral sclerosis.Akt-dependent phosphorylation of hepatic FoxO1 is compartmentalized on a WD40/ProF scaffold and is selectively inhibited by aPKC in early phases of diet-induced obesity.Kdo2-lipid A, a TLR4-specific agonist, induces de novo sphingolipid biosynthesis in RAW264.7 macrophages, which is essential for induction of autophagy Prenatal alcohol exposure triggers ceramide-induced apoptosis in neural crest-derived tissues concurrent with defective cranial development.Ceramide regulates atypical PKCzeta/lambda-mediated cell polarity in primitive ectoderm cells. A novel function of sphingolipids in morphogenesis.Complexation of c6-ceramide with cholesteryl phosphocholine - a potent solvent-free ceramide delivery formulation for cells in culture.Roles of sphingosine 1-phosphate on tumorigenesis Bioactive sphingolipids: metabolism and function Intraplantar-injected ceramide in rats induces hyperalgesia through an NF-κB- and p38 kinase-dependent cyclooxygenase 2/prostaglandin E2 pathway.Hepatic Atypical Protein Kinase C: An Inherited Survival-Longevity Gene that Now Fuels Insulin-Resistant Syndromes of Obesity, the Metabolic Syndrome and Type 2 Diabetes Mellitus Aberrant upregulation of astroglial ceramide potentiates oligodendrocyte injury.It's a lipid's world: bioactive lipid metabolism and signaling in neural stem cell differentiation.Nerve growth factor enhances the excitability of rat sensory neurons through activation of the atypical protein kinase C isoform, PKMζ.Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD).Self-renewal versus lineage commitment of embryonic stem cells: protein kinase C signaling shifts the balance Characterization of an apical ceramide-enriched compartment regulating ciliogenesis.Regulation of Chlamydomonas flagella and ependymal cell motile cilia by ceramide-mediated translocation of GSK3 Sphingolipids in cancer: regulation of pathogenesis and therapy.Inhibition of corneal inflammation by liposomal delivery of short-chain, C-6 ceramide.Ceramide signaling in cancer and stem cells.Examining the role of lipid mediators in diabetic retinopathy.Cardiac lipotoxicity: molecular pathways and therapeutic implications.Multimolecular complex of Par-4 and E2F1 binding to Smac promoter contributes to glutamate-induced apoptosis in human- bone mesenchymal stem cells.Ceramide and sphingosine-1-phosphate signaling in embryonic stem cell differentiation.Smart drugs for smarter stem cells: making SENSe (sphingolipid-enhanced neural stem cells) of ceramide.Direct interaction between the inhibitor 2 and ceramide via sphingolipid-protein binding is involved in the regulation of protein phosphatase 2A activity and signaling Ceramide-activated protein phosphatase involvement in insulin resistance via Akt, serine/arginine-rich protein 40, and ribonucleic acid splicing in L6 skeletal muscle cells Protein kinase C signalling in leukemia.Regulation of primary cilia formation by ceramide

P2860

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P2860

Direct binding to ceramide activates protein kinase Czeta before the formation of a pro-apoptotic complex with PAR-4 in differentiating stem cells

http://www.wikidata.org/entity/Q28251494

description

2005 nî lūn-bûn

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2005 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2005 թվականի հուլիսին հրատարակված գիտական հոդված

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2005年の論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年論文

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2005年论文

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name

Direct binding to ceramide act ...... in differentiating stem cells

@ast

Direct binding to ceramide act ...... in differentiating stem cells

@en

Direct binding to ceramide act ...... in differentiating stem cells

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type

label

Direct binding to ceramide act ...... in differentiating stem cells

@ast

Direct binding to ceramide act ...... in differentiating stem cells

@en

Direct binding to ceramide act ...... in differentiating stem cells

@nl

prefLabel

Direct binding to ceramide act ...... in differentiating stem cells

@ast

Direct binding to ceramide act ...... in differentiating stem cells

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Direct binding to ceramide act ...... in differentiating stem cells

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P1433

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P1433

Journal of Biological Chemistry

P1476

Direct binding to ceramide act ...... in differentiating stem cells

@en

P2093

Brian G Condie

http://www.w3.org/2001/XMLSchema#string

Erhard Bieberich

http://www.w3.org/2001/XMLSchema#string

Eric Tran

http://www.w3.org/2001/XMLSchema#string

Guanghu Wang

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Jeane Silva

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Kannan Krishnamurthy

http://www.w3.org/2001/XMLSchema#string

P2860

Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide

Identification of a unique core domain of par-4 sufficient for selective apoptosis induction in cancer cells

Protein kinase C lambda/iota (PKClambda/iota): a PKC isotype essential for the development of multicellular organisms

The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C

N-acylated serinol is a novel ceramide mimic inducing apoptosis in neuroblastoma cells

Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity

Regulation of mature T lymphocyte proliferation and differentiation by Par-4

The effect of ceramide on phosphatidylcholine membranes: a deuterium NMR study

Aggregation and fusion of vesicles composed of N-palmitoyl derivatives of membrane phospholipids.

The atypical protein kinase Cs. Functional specificity mediated by specific protein adapters

P304

26415-24

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scholarly article

P356

10.1074/JBC.M501492200

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28

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P478

280

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2005-07-15T00:00:00Z

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15901738

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P921

apoptotic process