Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1 - Wikidata - awgldk - TriplyDB

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

http://www.wikidata.org/entity/Q35668649

about

G-Protein-Coupled Lysophosphatidic Acid Receptors and Their Regulation of AKT Signaling Structural Studies of G Protein-Coupled Receptors The pathway of ligand entry from the membrane bilayer to a lipid G protein-coupled receptor.Structural evidence of the species-dependent albumin binding of the modified cyclic phosphatidic acid with cytotoxic properties Steroid binding to Autotaxin links bile salts and lysophosphatidic acid signalling Structural-Functional Features of the Thyrotropin Receptor: A Class A G-Protein-Coupled Receptor at Work High-resolution crystal structure of the human CB1 cannabinoid receptor.Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis.Solvent-accessibility of discrete residue positions in the polypeptide hormone glucagon by 19F-NMR observation of 4-fluorophenylalanine.Crystal Structure of the Human Cannabinoid Receptor CB1.Lys39-Lysophosphatidate Carbonyl Oxygen Interaction Locks LPA1 N-terminal Cap to the Orthosteric Site and partners Arg124 During Receptor Activation Synthesis and Biological Evaluation of Novel Phosphatidylcholine Analogues Containing Monoterpene Acids as Potent Antiproliferative Agents Lysophospholipids in coronary artery and chronic ischemic heart disease.Destabilization of Lysophosphatidic Acid Receptor 1 Reduces Cytokine Release and Protects Against Lung Injury.LPA1 is a key mediator of intracellular signalling and neuroprotection triggered by tetracyclic antidepressants in hippocampal neurons.Molecular mechanisms of target recognition by lipid GPCRs: relevance for cancer.GPCR-SSFE 2.0-a fragment-based molecular modeling web tool for Class A G-protein coupled receptors.Current strategies for protein production and purification enabling membrane protein structural biology.Allosteric communication pipelines in G-protein-coupled receptors.Structural studies of G protein-coupled receptors.7TM Domain Structure of Adhesion GPCRs.β2-Adrenergic Receptor Conformational Response to Fusion Protein in the Third Intracellular Loop.Micro-scale and rapid expression screening of highly expressed and/or stable membrane protein variants in Saccharomyces cerevisiae.Discovery of ONO-7300243 from a Novel Class of Lysophosphatidic Acid Receptor 1 Antagonists: From Hit to Lead.Structural insight into allosteric modulation of protease-activated receptor 2.Homology modeling of a Class A GPCR in the inactive conformation: A quantitative analysis of the correlation between model/template sequence identity and model accuracy 7×7 RMSD matrix: A new method for quantitative comparison of the transmembrane domain structures in the G-protein coupled receptors.LPA1 receptor-mediated thromboxane A2 release is responsible for lysophosphatidic acid-induced vascular smooth muscle contraction.A Structural Framework for GPCR Chemogenomics: What's In a Residue Number?Protein crystal quality oriented disulfide bond engineering.Structural insights into ligand recognition by the lysophosphatidic acid receptor LPA6.Molecular Dynamics Methodologies for Probing Cannabinoid Ligand/Receptor Interaction.Methods for the Development of In Silico GPCR Models.Closely related, yet unique: Distinct homo- and heterodimerization patterns of G protein coupled chemokine receptors and their fine-tuning by cholesterol.In silico studies targeting G-protein coupled receptors for drug research against Parkinson's disease.Discovery of a Slow Tight Binding LPA1 Antagonist (ONO-0300302) for the Treatment of Benign Prostatic Hyperplasia.G protein-coupled receptors: the evolution of structural insight.'Crystal' Clear? Lysophospholipid Receptor Structure Insights and Controversies Overexpression and Functional Stabilization of Recombinant Human Lysophosphatidic Acid Receptor 1 Using an Amphiphatic Polymer

P2860

Q26767279-A0F5808B-F4EC-4C49-A952-F3F2470208B6 Q26783016-C4FF78BF-97CE-4C10-8B38-ED20AB6CCA6F Q27334167-E41B6F7E-C8E3-4E0F-A417-40E973CDB702 Q27704759-CC9F1BB6-2B7E-4577-B04F-4D91D1D00EB7 Q28274830-8FD9139D-D0C3-4FB9-A714-B1F998F6FAFE Q30401802-B453A0EC-1C7B-4EAE-81A8-63121804F0C9 Q33694212-D13E1EA8-6F9F-4653-BD26-4530F8660FC1 Q33759830-ED94B088-2AEA-4873-A56E-ABB4F037BDC8 Q33843966-D53335DD-B739-4BD4-B108-CBBC65243A76 Q34543208-EC343EF8-BD93-495F-B8A7-A96DC6CF8522 Q35974518-B9F6DCE3-957B-45D7-A4EF-AF677989F680 Q36054396-010370E0-D416-442A-9B50-0D472D4293BE Q36198168-A17F08E7-D05B-40D6-ACDB-DA4CBAEBD3FB Q37221686-1FD8DCFB-03C5-4763-B3DE-9B155BABF9D8 Q38620926-99D964F7-7217-4CA8-BF4B-A6BAAF215CA7 Q38660494-A8DBA3EC-16A1-4BDB-8DCF-0687260C6471 Q38743168-D37419C5-9ED0-4CFC-82B1-DF35660D10A6 Q38787163-EC80F42B-043B-4F88-858F-8CBF82BCB0E6 Q38920318-EFC5D08B-FB1B-4905-9E70-BAB8601E4296 Q38987183-A370B4B8-7546-4A6A-94AE-CBA6522842E2 Q39004681-C3BFCA99-599B-4E3C-A56C-1069DE505118 Q39191447-E2553AC9-B3EB-4413-AC2B-5AC51DA7FF92 Q41656733-C6BAA07F-0F97-409F-A98C-B769A43A274B Q41992687-28AED3DE-05B3-4EB6-A94C-D36CBD6B7447 Q42152331-26617F55-AF0E-4B35-8392-D9AC6C7AB04A Q42806068-485608E4-6FE0-4863-A371-CC4CE200113A Q45228067-222FE1B4-3461-4A29-826D-E538972E99D3 Q46228136-5C729F58-BF00-448F-9C3F-9A5D9C93F8F9 Q47348737-CB6FDB9F-F243-453A-9351-62FE4D03AA70 Q47438356-01F5B752-8210-4E78-B004-B9686DE7B219 Q47973099-12BC9804-5ECD-4808-B512-2707914EA3E1 Q48020118-D5EB0BD9-D5CD-4061-842D-E702E7C9C093 Q48020126-3048D336-94F8-4FF0-9862-69230056FAA8 Q52660783-2989B849-4685-418F-A7A9-28F9D42F6DD1 Q52665081-15232671-4116-4F6D-BC1B-065024212A2C Q52743603-86A32793-6D5C-4E9A-A9CA-4112F369DFC6 Q55278334-53044532-CBEC-41EC-AC56-980B80DB80ED Q57789232-F2263F43-5DC5-4C67-8F90-14B3216F08AF Q58340391-03A70340-D3FA-4D0D-8A71-8DAEDDCAD0EF

P2860

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

http://www.wikidata.org/entity/Q35668649

description

2015 nî lūn-bûn

@nan

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

2015年论文

@zh

2015年论文

@zh-cn

name

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

@ast

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

@en

type

label

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

@ast

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

@en

prefLabel

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

@ast

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

@en

P1433

Q35668649-70EE606B-F536-4EF1-A3B2-61547A9279DD

P1476

Q35668649-C780519A-EC85-4CC8-B0CC-80589EF2AD2F

P2093

Q35668649-01FCF749-F55D-4AB7-A2D7-12D1BBC3EAD6

Q35668649-1E18EA82-E2DF-4835-BF98-C14F056A9186

Q35668649-244D8D8D-BDC3-439E-885B-8EBBED73794B

Q35668649-316FD7D9-30EB-4A1A-AE3E-E6457013F858

Q35668649-428CDA4D-6C39-48F4-A549-4EC49709813C

Q35668649-608595F3-ADD0-48C3-94E7-385731B51736

Q35668649-73DA521E-9568-46AE-B12B-B3FD9DF5176B

Q35668649-744EAEC3-6C84-4AC3-A53D-4446CEBDE524

Q35668649-7FAF5AD7-57A8-4A4A-B97A-7C927281CAD9

Q35668649-89A92850-2ED2-4AE2-99CA-601308F2E798

P2860

Q35668649-04AF6A32-D797-41F0-B9D1-378AD04FE08D

Q35668649-0B364890-16C2-49F3-86DB-560AE4C2CD4F

Q35668649-0B9E1C54-063F-44B7-AA9B-8232D73C8B1B

Q35668649-1A102FF4-6790-4853-81D7-EFBA67318BA0

Q35668649-1AD7825C-100C-4C02-9ED6-2BD7E1AACDF9

Q35668649-1DB60B8D-ADF4-441F-8AA8-467559FA50E7

Q35668649-22D38C7C-162E-48AA-8C00-0DA394E637A0

Q35668649-38950121-DA99-46E4-8B87-54734F8B28C5

Q35668649-38CBDC66-3B38-4594-A76E-B357107B01E7

Q35668649-3A578092-4DF5-4788-9E92-04607C662F91

P304

Q35668649-D06061C8-D52E-404B-85F0-E18E20DA47EF

P31

Q35668649-8A03DA93-9EB7-47B1-BBD8-CDA0BB217AAF

P356

Q35668649-4B56B38C-3CFC-4E1F-B593-0C7B9D9F5368

P407

Q35668649-357287B1-7369-40A1-B226-39C493CB7556

P433

Q35668649-125AB876-1687-40D0-9E45-DC410F9F196D

P478

Q35668649-6B2CEC72-A23B-4668-B183-08DBC7038215

P50

Q35668649-7DD6822F-700C-4FDA-A75D-EE23826524C1

Q35668649-9CD30613-E400-4D7C-AE2B-D23481B9370F

Q35668649-FC6181DD-0496-471F-AB4F-EC8846BBEE53

P577

Q35668649-8FD4E02E-3140-427D-8221-243352D53AC3

P698

Q35668649-27061FC7-7E1F-4423-8BA4-9C9F1616A63C

P932

Q35668649-90117210-A71B-4E04-B481-0F37BA38150B

P356

J.CELL.2015.06.002

P1433

P1476

Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1

@en

P2093

Caroline Rodgers

http://www.w3.org/2001/XMLSchema#string

Christopher B Roth

http://www.w3.org/2001/XMLSchema#string

Dora Warshaviak

http://www.w3.org/2001/XMLSchema#string

Guillermo Asmar-Rovira

http://www.w3.org/2001/XMLSchema#string

Gye Won Han

http://www.w3.org/2001/XMLSchema#string

Hirotaka Mizuno

http://www.w3.org/2001/XMLSchema#string

Jeffrey Velasquez

http://www.w3.org/2001/XMLSchema#string

Jerold Chun

http://www.w3.org/2001/XMLSchema#string

Jill E Chrencik

http://www.w3.org/2001/XMLSchema#string

Mark T Griffith

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of a lipid G protein-coupled receptor

Ventricular zone gene-1 (vzg-1) encodes a lysophosphatidic acid receptor expressed in neurogenic regions of the developing cerebral cortex

Structural basis of substrate discrimination and integrin binding by autotaxin

A single receptor encoded by vzg-1/lpA1/edg-2 couples to G proteins and mediates multiple cellular responses to lysophosphatidic acid

A biosynthetic pathway for anandamide

Crystal structure of autotaxin and insight into GPCR activation by lipid mediators

Efficient selection for high-expression transfectants with a novel eukaryotic vector

The emerging role of lysophosphatidic acid in cancer

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

A second endogenous cannabinoid that modulates long-term potentiation

P304

1633-1643

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.CELL.2015.06.002

http://www.w3.org/2001/XMLSchema#string

P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

161

http://www.w3.org/2001/XMLSchema#string

P50

Raymond C Stevens

Masahiko Terakado

P577

2015-06-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

26091040

http://www.w3.org/2001/XMLSchema#string

P932

4476059

http://www.w3.org/2001/XMLSchema#string