Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury.
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SOD therapeutics: latest insights into their structure-activity relationships and impact on the cellular redox-based signaling pathwaysThe Toll-Like Receptor 5 Agonist Entolimod Mitigates Lethal Acute Radiation Syndrome in Non-Human PrimatesAEOL 10150 Mitigates Radiation-Induced Lung Injury in the Nonhuman Primate: Morbidity and Mortality are Administration Schedule-Dependent.Hypoxia inducible factor 1alpha signaling in fractionated radiation-induced lung injury: role of oxidative stress and tissue hypoxia.Treatment with the catalytic metalloporphyrin AEOL 10150 reduces inflammation and oxidative stress due to inhalation of the sulfur mustard analog 2-chloroethyl ethyl sulfide.Superoxide dismutase mimics: chemistry, pharmacology, and therapeutic potentialProteomic analysis of radiation-induced changes in rat lung: Modulation by the superoxide dismutase mimetic MnTE-2-PyP(5+).Prevention and mitigation of acute death of mice after abdominal irradiation by the antioxidant N-acetyl-cysteine (NAC).Design of Mn porphyrins for treating oxidative stress injuries and their redox-based regulation of cellular transcriptional activities.Flaxseed Mitigates Acute Oxidative Lung Damage in a Mouse Model of Repeated Radiation and Hyperoxia Exposure Associated with Space Exploration.Mitigation of radiation-induced lung injury by genistein and EUK-207.Diverse functions of cationic Mn(III) N-substituted pyridylporphyrins, recognized as SOD mimicsThe extent of irradiation-induced long-term visceral organ damage depends on cranial/brain exposure.Investigations into the role of inflammation in normal tissue response to irradiation.Novel synthetic SOD/catalase mimetics can mitigate capillary endothelial cell apoptosis caused by ionizing radiation.Targeting the TGF-beta1 pathway to prevent normal tissue injury after cancer therapy.Mitigation of lung injury after accidental exposure to radiation.After the bomb drops: a new look at radiation-induced multiple organ dysfunction syndrome (MODS)Dose Optimization Study of AEOL 10150 as a Mitigator of Radiation-Induced Lung Injury in CBA/J Mice.Anti-IL-6 receptor antibody does not ameliorate radiation pneumonia in mice.Extracellular superoxide dismutase in pulmonary fibrosisMitigation of radiation-induced lung injury with EUK-207 and genistein: effects in adolescent ratsTemporal expression of hypoxia-regulated genes is associated with early changes in redox status in irradiated lungOxidative stress mediates radiation lung injury by inducing apoptosis.A combination of two antioxidants (an SOD mimic and ascorbate) produces a pro-oxidative effect forcing Escherichia coli to adapt via induction of oxyR regulon.Exploring the role of HIF-1 in early angiogenesis and response to radiotherapy.Short-term treatment with a SOD/catalase mimetic, EUK-207, mitigates pneumonitis and fibrosis after single-dose total-body or whole-thoracic irradiationSubcutaneous administration of bovine superoxide dismutase protects lungs from radiation-induced lung injury.Comparison of two Mn porphyrin-based mimics of superoxide dismutase in pulmonary radioprotectionPharmacokinetics of the potent redox-modulating manganese porphyrin, MnTE-2-PyP(5+), in plasma and major organs of B6C3F1 miceEarly and late administration of MnTE-2-PyP5+ in mitigation and treatment of radiation-induced lung damageAntioxidants as potential therapeutics for lung fibrosis.Changing the energy of an immune responseCatalase and glutathione peroxidase mimics.Salen Mn complexes mitigate radiation injury in normal tissues.Dietary flaxseed prevents radiation-induced oxidative lung damage, inflammation and fibrosis in a mouse model of thoracic radiation injury.Antiangiogenic action of redox-modulating Mn(III) meso-tetrakis(N-ethylpyridinium-2-yl)porphyrin, MnTE-2-PyP(5+), via suppression of oxidative stress in a mouse model of breast tumorExtracellular superoxide dismutase regulates cardiac function and fibrosis.Antioxidant therapeutics: Pandora's box.Redox-modulated phenomena and radiation therapy: the central role of superoxide dismutases.
P2860
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P2860
Long-term administration of a small molecular weight catalytic metalloporphyrin antioxidant, AEOL 10150, protects lungs from radiation-induced injury.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Long-term administration of a ...... from radiation-induced injury.
@ast
Long-term administration of a ...... from radiation-induced injury.
@en
type
label
Long-term administration of a ...... from radiation-induced injury.
@ast
Long-term administration of a ...... from radiation-induced injury.
@en
prefLabel
Long-term administration of a ...... from radiation-induced injury.
@ast
Long-term administration of a ...... from radiation-induced injury.
@en
P2093
P2860
P1476
Long-term administration of a ...... from radiation-induced injury.
@en
P2093
Brian J Day
Elaine Alexander
Ines Batinic-Haberle
Mark W Dewhirst
Mitchell S Anscher
Zahid N Rabbani
Zeljko Vujaskovic
P2860
P304
P356
10.1016/J.IJROBP.2006.09.053
P407
P577
2007-02-01T00:00:00Z