An interaction between the human T cell leukemia virus type 1 basic leucine zipper factor (HBZ) and the KIX domain of p300/CBP contributes to the down-regulation of tax-dependent viral transcription by HBZ
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The HTLV-1 Tax interactomeTranscriptional and Epigenetic Regulatory Mechanisms Affecting HTLV-1 ProvirusHTLV-1 Infection and Adult T-Cell Leukemia/Lymphoma-A Tale of Two Proteins: Tax and HBZMultifaceted functions and roles of HBZ in HTLV-1 pathogenesisThe Role of HBZ in HTLV-1-Induced OncogenesisModes of Human T Cell Leukemia Virus Type 1 Transmission, Replication and PersistenceHistone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancyNovel interactions between the HTLV antisense proteins HBZ and APH-2 and the NFAR protein family: Implications for the HTLV lifecyclesRNA stability regulates human T cell leukemia virus type 1 gene expression in chronically-infected CD4 T cells.Characterization of simian T-cell leukemia virus type 1 in naturally infected Japanese macaques as a model of HTLV-1 infection.Human T-cell leukemia virus type 3 (HTLV-3) and HTLV-4 antisense-transcript-encoded proteins interact and transactivate Jun family-dependent transcription via their atypical bZIP motifBiophysical analysis of HTLV-1 particles reveals novel insights into particle morphology and Gag stochiometry.Requirement of the human T-cell leukemia virus p12 and p30 products for infectivity of human dendritic cells and macaques but not rabbitsAcetylation of the c-MYC oncoprotein is required for cooperation with the HTLV-1 p30(II) accessory protein and the induction of oncogenic cellular transformation by p30(II)/c-MYC.HTLV-1 HBZ protein deregulates interactions between cellular factors and the KIX domain of p300/CBP.Suppression of HTLV-1 replication by Tax-mediated rerouting of the p13 viral protein to nuclear speckles.HTLV-1 bZIP factor enhances TGF-β signaling through p300 coactivator.Polarized expression of the membrane ASP protein derived from HIV-1 antisense transcription in T cells.Human T Lymphotropic Virus Type 1 (HTLV-1): Molecular Biology and Oncogenesis.Making sense out of antisense transcription in human T-cell lymphotropic viruses (HTLVs).Direct inhibition of RNAse T2 expression by the HTLV-1 viral protein Tax.Converging strategies in expression of human complex retrovirusesIdentification and characterization of HTLV-1 HBZ post-translational modifications.Human T-cell lymphotropic virus type 3 (HTLV-3)- and HTLV-4-derived antisense transcripts encode proteins with similar Tax-inhibiting functions but distinct subcellular localizationLocalization, quantification and interaction with host factors of endogenous HTLV-1 HBZ protein in infected cells and ATLHTLV-1 bZIP Factor Impairs Anti-viral Immunity by Inducing Co-inhibitory Molecule, T Cell Immunoglobulin and ITIM Domain (TIGIT).The HTLV-1-encoded protein HBZ directly inhibits the acetyl transferase activity of p300/CBP.Human T-cell leukemia virus type 1 (HTLV-1) bZIP factor requires cellular transcription factor JunD to upregulate HTLV-1 antisense transcription from the 3' long terminal repeat.Human T-cell leukemia virus type 2 antisense viral protein 2 is dispensable for in vitro immortalization but functions to repress early virus replication in vivo.HTLV-1 bZIP Factor Enhances T-Cell Proliferation by Impeding the Suppressive Signaling of Co-inhibitory ReceptorsHTLV tax: a fascinating multifunctional co-regulator of viral and cellular pathwaysPRMT5 Is Upregulated in HTLV-1-Mediated T-Cell Transformation and Selective Inhibition Alters Viral Gene Expression and Infected Cell Survival.Functional Comparison of HBZ and the Related APH-2 Protein Provides Insight into Human T-Cell Leukemia Virus Type 1 Pathogenesis.Permissive Sense and Antisense Transcription from the 5' and 3' Long Terminal Repeats of Human T-Cell Leukemia Virus Type 1Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1.Functional comparison of antisense proteins of HTLV-1 and HTLV-2 in viral pathogenesisThe HBZ gene, a key player in HTLV-1 pathogenesis.Impaired expression of DICER and some microRNAs in HBZ expressing cells from acute adult T-cell leukemia patients.Human T-cell leukemia virus type 2 produces a spliced antisense transcript encoding a protein that lacks a classic bZIP domain but still inhibits Tax2-mediated transcription.Mechanisms of HTLV-1 persistence and transformation.
P2860
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P2860
An interaction between the human T cell leukemia virus type 1 basic leucine zipper factor (HBZ) and the KIX domain of p300/CBP contributes to the down-regulation of tax-dependent viral transcription by HBZ
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
An interaction between the hum ...... ent viral transcription by HBZ
@ast
An interaction between the hum ...... ent viral transcription by HBZ
@en
type
label
An interaction between the hum ...... ent viral transcription by HBZ
@ast
An interaction between the hum ...... ent viral transcription by HBZ
@en
prefLabel
An interaction between the hum ...... ent viral transcription by HBZ
@ast
An interaction between the hum ...... ent viral transcription by HBZ
@en
P2093
P2860
P356
P1476
An interaction between the hum ...... ent viral transcription by HBZ
@en
P2093
Benoit Barbeau
Charlotte André-Arpin
Isabelle Clerc
Isabelle Lemasson
Jean-Michel Mesnard
Pamela Cook
P2860
P304
23903-23913
P356
10.1074/JBC.M803116200
P407
P577
2008-07-02T00:00:00Z