RalA functions as an indispensable signal mediator for the nutrient-sensing system
about
RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assemblyRegulation of TOR by small GTPasesSpatial regulation of the mTORC1 system in amino acids sensing pathwayMammalian target of rapamycin (mTOR): conducting the cellular signaling symphonyLeucine and mTORC1: a complex relationshipRegulation of mTORC1 by PI3K signalingRole of amino acid transporters in amino acid sensingNutrient regulation of the mTOR complex 1 signaling pathwayIs REDD1 a Metabolic Éminence Grise?Ral GTPases: crucial mediators of exocytosis and tumourigenesisNucleolar stress induces ubiquitination-independent proteasomal degradation of PICT1 proteinFMRP S499 is phosphorylated independent of mTORC1-S6K1 activity.Differential requirement of CAAX-mediated posttranslational processing for Rheb localization and signalingTOR-dependent control of autophagy: biting the hand that feedsAuxin Signaling in Regulation of Plant Translation ReinitiationRegulation of Weibel-Palade body exocytosis by alpha-synuclein in endothelial cells.MEK-ERK1/2-dependent FLNA overexpression promotes abnormal dendritic patterning in tuberous sclerosis independent of mTOR.Nutrient signaling to mTOR and cell growth.Direct Interaction between Ras Homolog Enriched in Brain and FK506 Binding Protein 38 in Cashmere Goat Fetal Fibroblast Cells.Growing knowledge of the mTOR signaling network.Ral GTPase promotes asymmetric Notch activation in the Drosophila eye in response to Frizzled/PCP signaling by repressing ligand-independent receptor activationPhospholipase D mediates nutrient input to mammalian target of rapamycin complex 1 (mTORC1).Phosphatidic acid activates mammalian target of rapamycin complex 1 (mTORC1) kinase by displacing FK506 binding protein 38 (FKBP38) and exerting an allosteric effect.FKBP38 peptidylprolyl isomerase promotes the folding of cystic fibrosis transmembrane conductance regulator in the endoplasmic reticulumActivating the translational repressor 4E-BP or reducing S6K-GSK3β activity prevents accelerated axon growth induced by hyperactive mTOR in vivo.Microtubule-associated protein/microtubule affinity-regulating kinase 4 (MARK4) is a negative regulator of the mammalian target of rapamycin complex 1 (mTORC1).Negative regulation of the RalGAP complex by 14-3-3.Phosphatidic acid and lipid-sensing by mTORRheb activation in subventricular zone progenitors leads to heterotopia, ectopic neuronal differentiation, and rapamycin-sensitive olfactory micronodules and dendrite hypertrophy of newborn neurons.Normalizing translation through 4E-BP prevents mTOR-driven cortical mislamination and ameliorates aberrant neuron integration.Ral and Rheb GTPase activating proteins integrate mTOR and GTPase signaling in aging, autophagy, and tumor cell invasion.Involvement of members of the Rab family and related small GTPases in autophagosome formation and maturation.Mammalian target of rapamycin and the kidney. I. The signaling pathway.p62: a versatile multitasker takes on cancer.A molecular rheostat at the interface of cancer and diabetesCurrent models of mammalian target of rapamycin complex 1 (mTORC1) activation by growth factors and amino acids.Key mediators of intracellular amino acids signaling to mTORC1 activation.RalGDS-dependent cardiomyocyte autophagy is required for load-induced ventricular hypertrophy.FKBPs and the Akt/mTOR pathwayULK1 inhibits mTORC1 signaling, promotes multisite Raptor phosphorylation and hinders substrate binding.
P2860
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P2860
RalA functions as an indispensable signal mediator for the nutrient-sensing system
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
RalA functions as an indispensable signal mediator for the nutrient-sensing system
@ast
RalA functions as an indispensable signal mediator for the nutrient-sensing system
@en
type
label
RalA functions as an indispensable signal mediator for the nutrient-sensing system
@ast
RalA functions as an indispensable signal mediator for the nutrient-sensing system
@en
prefLabel
RalA functions as an indispensable signal mediator for the nutrient-sensing system
@ast
RalA functions as an indispensable signal mediator for the nutrient-sensing system
@en
P2093
P2860
P356
P1476
RalA functions as an indispensable signal mediator for the nutrient-sensing system
@en
P2093
Hiroshi Nishina
Kentaro Hanada
Makoto Murakami
Masahiko Tanaka
Tomohiko Maehama
Yasunori Kanaho
P2860
P304
35053-35059
P356
10.1074/JBC.M805822200
P407
P577
2008-10-23T00:00:00Z