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Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological SynapseConcerning immune synapses: a spatiotemporal timelineBiophysical Aspects of T Lymphocyte Activation at the Immune SynapseInvestigative and clinical applications of synthetic immune synapsesMicro- and nanoscale engineering of cell signalingαβ TCR-mediated recognition: relevance to tumor-antigen discovery and cancer immunotherapyLinking form to function: Biophysical aspects of artificial antigen presenting cell designIndoctrinating T cells to attack pathogens through homeschoolingMechanical regulation of T-cell functionsControversy and consensus regarding myosin II function at the immunological synapseRole of actin dependent nuclear deformation in regulating early gene expressionT Lymphocyte Myosin IIA is Required for Maturation of the Immunological SynapseCD28 and CD3 have complementary roles in T-cell traction forces.Cytoskeletal forces during signaling activation in Jurkat T-cells.F-actin flow drives affinity maturation and spatial organization of LFA-1 at the immunological synapse.Nuclear envelope lamin-A couples actin dynamics with immunological synapse architecture and T cell activation.Actin polymerization-dependent activation of Cas-L promotes immunological synapse stabilityConstitutively oxidized CXXC motifs within the CD3 heterodimeric ectodomains of the T cell receptor complex enforce the conformation of juxtaposed segments.Accumulation of serial forces on TCR and CD8 frequently applied by agonist antigenic peptides embedded in MHC molecules triggers calcium in T cells.Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.Ligand-mediated friction determines morphodynamics of spreading T cellsForce-dependent transition in the T-cell receptor β-subunit allosterically regulates peptide discrimination and pMHC bond lifetime.The dendritic cell cytoskeleton promotes T cell adhesion and activation by constraining ICAM-1 mobilityHuman Primary Immune Cells Exhibit Distinct Mechanical Properties that Are Modified by Inflammation.Micropatterning of TCR and LFA-1 ligands reveals complementary effects on cytoskeleton mechanics in T cells.Actin engine in immunological synapseA microfluidic platform reveals differential response of regulatory T cells to micropatterned costimulation arrays.Dissection of mechanical force in living cells by super-resolved traction force microscopy.Insights from in situ analysis of TCR-pMHC recognition: response of an interaction network.Structural and biophysical insights into the role of CD4 and CD8 in T cell activation.Synthesis of nanostructured and biofunctionalized water-in-oil droplets as tools for homing T cellsCoordinate control of cytoskeletal remodeling and calcium mobilization during T-cell activationCross talk between CD3 and CD28 is spatially modulated by protein lateral mobilityThe structural basis of αβ T-lineage immune recognition: TCR docking topologies, mechanotransduction, and co-receptor function.T cell antigen receptor activation and actin cytoskeleton remodeling.Nuclear envelope lamin-A as a coordinator of T cell activation.Codification of bidentate pMHC interaction with TCR and its co-receptor.B Cells use Conserved Polarity Cues to Regulate Their Antigen Processing and Presentation Functions.Contractile actomyosin arcs promote the activation of primary mouse T cells in a ligand-dependent manner.Catch Bonds at T Cell Interfaces: Impact of Surface Reorganization and Membrane Fluctuations.
P2860
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P2860
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Mechanosensing in T lymphocyte activation
@ast
Mechanosensing in T lymphocyte activation
@en
type
label
Mechanosensing in T lymphocyte activation
@ast
Mechanosensing in T lymphocyte activation
@en
prefLabel
Mechanosensing in T lymphocyte activation
@ast
Mechanosensing in T lymphocyte activation
@en
P2860
P50
P1433
P1476
Mechanosensing in T lymphocyte activation
@en
P2093
Edward Judokusumo
Lance C Kam
P2860
P356
10.1016/J.BPJ.2011.12.011
P407
P577
2012-01-01T00:00:00Z