Focal adhesion kinase-related protein tyrosine kinase Pyk2 in T-cell activation and function.
about
Pyk2 inhibition of p53 as an adaptive and intrinsic mechanism facilitating cell proliferation and survivalPyk2 mediates endothelin-1 signaling via p130Cas/BCAR3 cascade and regulates human glomerular mesangial cell adhesion and spreadingComparison of T cell receptor-induced proximal signaling and downstream functions in immortalized and primary T cellsThe proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling.CD28 and CD3 have complementary roles in T-cell traction forces.RETRACTED: Functional activation of proline-rich tyrosine kinase2 (PYK2) in peripheral blood mononuclear cells from patients with systemic lupus erythematosus.Functions of the FAK family kinases in T cells: beyond actin cytoskeletal rearrangement.Non-catalytic functions of Pyk2 and Fyn regulate late stage adhesion in human T cells.A role for the protein tyrosine phosphatase CD45 in macrophage adhesion through the regulation of paxillin degradation.Proline-rich tyrosine kinase 2 controls PI3-kinase activation downstream of the T cell antigen receptor in human T cells.Differential expression of FAK and Pyk2 in metastatic and non-metastatic EL4 lymphoma cell linesMechanosensing in T lymphocyte activationFocal adhesion kinase negatively regulates Lck function downstream of the T cell antigen receptor.The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties.B cell receptor-induced phosphorylation of Pyk2 and focal adhesion kinase involves integrins and the Rap GTPases and is required for B cell spreading.Differential function of PTPalpha and PTPalpha Y789F in T cells and regulation of PTPalpha phosphorylation at Tyr-789 by CD45.LFA-1 activates focal adhesion kinases FAK1/PYK2 to generate LAT-GRB2-SKAP1 complexes that terminate T-cell conjugate formationThe kinase Itk and the adaptor TSAd change the specificity of the kinase Lck in T cells by promoting the phosphorylation of Tyr192.Regulation of the tyrosine kinase Pyk2 by calcium is through production of reactive oxygen species in cytotoxic T lymphocytes.The T cell receptor-mediated phosphorylation of Pyk2 tyrosines 402 and 580 occurs via a distinct mechanism than other receptor systems.Mycobacterium tuberculosis Mce3C promotes mycobacteria entry into macrophages through activation of β2 integrin-mediated signalling pathway.T-cell co-stimulation through the CD2 and CD28 co-receptors induces distinct signalling responses.Pyk2 Controls Integrin-Dependent CTL Migration through Regulation of De-Adhesion.Proline-Rich Protein Tyrosine Kinase 2 in Inflammation and Cancer.Glycerol monolaurate induces filopodia formation by disrupting the association between LAT and SLP-76 microclusters.Expression and activation of proline-rich tyrosine kinase 2 (PYK2) in peripheral blood mononuclear cells from patients with systemic lupus erythematosus.
P2860
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P2860
Focal adhesion kinase-related protein tyrosine kinase Pyk2 in T-cell activation and function.
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Focal adhesion kinase-related ...... -cell activation and function.
@ast
Focal adhesion kinase-related ...... -cell activation and function.
@en
type
label
Focal adhesion kinase-related ...... -cell activation and function.
@ast
Focal adhesion kinase-related ...... -cell activation and function.
@en
prefLabel
Focal adhesion kinase-related ...... -cell activation and function.
@ast
Focal adhesion kinase-related ...... -cell activation and function.
@en
P356
P1433
P1476
Focal adhesion kinase-related ...... -cell activation and function.
@en
P2093
Hanne L Ostergaard
Tara L Lysechko
P2888
P304
P356
10.1385/IR:31:3:267
P577
2005-01-01T00:00:00Z
P6179
1034890143