HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway
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Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic TargetsThe Interplay of Reactive Oxygen Species, Hypoxia, Inflammation, and Sirtuins in Cancer Initiation and ProgressionNew Findings on Breast Cancer Stem Cells: A ReviewSignaling Circuits and Regulation of Immune Suppression by Ovarian Tumor-Associated MacrophagesRedox Regulation in Cancer Stem CellsRole of Notch signaling in the mammalian heartA new prospect in cancer therapy: targeting cancer stem cells to eradicate cancerSustained proliferation in cancer: Mechanisms and novel therapeutic targetsMetabolic tumor profiling with pH, oxygen, and glucose chemosensors on a quantum dot scaffold.Ataxin-1 regulates epithelial-mesenchymal transition of cervical cancer cells.HIF1α regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxiaEupolyphaga sinensis walker displays inhibition on hepatocellular carcinoma through regulating cell growth and metastasis signaling.Notch signaling change in pulmonary vascular remodeling in rats with pulmonary hypertension and its implication for therapeutic intervention.Expression of the RNA helicase DDX3 and the hypoxia response in breast cancerEvaluation of anti-HIF and anti-angiogenic properties of honokiol for the treatment of ocular neovascular diseases.Hypoxia-inducible factor-1α regulates the expression of L-type voltage-dependent Ca(2+) channels in PC12 cells under hypoxia.A combined gene signature of hypoxia and notch pathway in human glioblastoma and its prognostic relevance.The HIF-1 inhibitor YC-1 decreases reactive astrocyte formation in a rodent ischemia modelExposure of tumor-associated macrophages to apoptotic MCF-7 cells promotes breast cancer growth and metastasis.Cancer stem cells in glioblastomaHistological Characterization of the Tumorigenic "Peri-Necrotic Niche" Harboring Quiescent Stem-Like Tumor Cells in GlioblastomaThe updated biology of hypoxia-inducible factorHIF-1 at the crossroads of hypoxia, inflammation, and cancer.Hes1: a key role in stemness, metastasis and multidrug resistance.Clinical and prognostic significance of HIF-1α in glioma patients: a meta-analysis.The Cancer Genome Atlas Analysis Predicts MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma.Prolonged inhibition of glioblastoma xenograft initiation and clonogenic growth following in vivo Notch blockadeDesign and in vitro activities of N-alkyl-N-[(8-R-2,2-dimethyl-2H-chromen-6-yl)methyl]heteroarylsulfonamides, novel, small-molecule hypoxia inducible factor-1 pathway inhibitors and anticancer agents.Priming adult stem cells by hypoxic pretreatments for applications in regenerative medicine.The biological kinship of hypoxia with CSC and EMT and their relationship with deregulated expression of miRNAs and tumor aggressiveness.Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling.Evidence that collaboration between HIF-1α and Notch-1 promotes neuronal cell death in ischemic stroke.Hypoxia-NOTCH1-SOX2 signaling is important for maintaining cancer stem cells in ovarian cancer.Valproic acid for the treatment of malignant gliomas: review of the preclinical rationale and published clinical results.Endothelial cell metabolism and implications for cancer therapy.Critical multiple angiogenic factors secreted by glioblastoma stem-like cells underline the need for combinatorial anti-angiogenic therapeutic strategies.Modulators of HIF1α and NFkB in Cancer Treatment: Is it a Rational Approach for Controlling Malignant Progression?Hypoxia-inducible factor-1α as prognostic marker.The impact of age on oncogenic potential: tumor-initiating cells and the brain microenvironment.Cancer biomarker discovery: current status and future perspectives.
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P2860
HIF-1α is critical for hypoxia-mediated maintenance of glioblastoma stem cells by activating Notch signaling pathway
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
HIF-1α is critical for hypoxia ...... vating Notch signaling pathway
@ast
HIF-1α is critical for hypoxia ...... vating Notch signaling pathway
@en
type
label
HIF-1α is critical for hypoxia ...... vating Notch signaling pathway
@ast
HIF-1α is critical for hypoxia ...... vating Notch signaling pathway
@en
prefLabel
HIF-1α is critical for hypoxia ...... vating Notch signaling pathway
@ast
HIF-1α is critical for hypoxia ...... vating Notch signaling pathway
@en
P2093
P2860
P356
P1476
HIF-1α is critical for hypoxia ...... vating Notch signaling pathway
@en
P2093
P2860
P2888
P304
P356
10.1038/CDD.2011.95
P50
P577
2011-08-05T00:00:00Z