Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients. - Wikidata - awgldk - TriplyDB

Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.

Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.

http://www.wikidata.org/entity/Q35691070

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In type 1 diabetes a subset of anti-coxsackievirus B4 antibodies recognize autoantigens and induce apoptosis of pancreatic beta cells Immunoproteomic Profiling of Antiviral Antibodies in New-Onset Type 1 Diabetes Using Protein Arrays Immune signaling by RIG-I-like receptors Application of IgG-derived natural Treg epitopes (IgG Tregitopes) to antigen-specific tolerance induction in a murine model of type 1 diabetes Enterovirus infection and type 1 diabetes mellitus: systematic review and meta-analysis of observational molecular studies Where, How, and When: Positioning Posttranslational Modification Within Type 1 Diabetes Pathogenesis Mechanisms of Beta Cell Dysfunction Associated With Viral Infection How Does Thymus Infection by Coxsackievirus Contribute to the Pathogenesis of Type 1 Diabetes?The impact of anti-inflammatory cytokines on the pancreatic β-cell Immunology in the clinic review series; focus on type 1 diabetes and viruses: how viral infections modulate beta cell function Enterovirus and type 1 diabetes: What is the matter?Immunology in the clinic review series; focus on type 1 diabetes and viruses: the enterovirus link to type 1 diabetes: critical review of human studies Dendritic cell subsets in type 1 diabetes: friend or foe?Virus infections in type 1 diabetes The Juvenile Diabetes Research Foundation Network for Pancreatic Organ Donors with Diabetes (nPOD) Program: goals, operational model and emerging findings Functional Significance of CD57 Expression on Human NK Cells and Relevance to Disease Insulitis in human type 1 diabetes: a comparison between patients and animal models TLR7/9 versus TLR3/MDA5 signaling during virus infections and diabetes Infection as a cause of type 1 diabetes?Genetics, pathogenesis and clinical interventions in type 1 diabetes Type 1 diabetes: translating mechanistic observations into effective clinical outcomes An image-based genetic assay identifies genes in T1D susceptibility loci controlling cellular antiviral immunity in mouse Potential viral pathogenic mechanism in human type 1 diabetes Spatiotemporal Dynamics of Insulitis in Human Type 1 Diabetes Do viral infections protect from or enhance type 1 diabetes and how can we tell the difference?Next-generation sequencing for viruses in children with rapid-onset type 1 diabetes.Monitoring of antigen-specific CD8 T cells in patients with type 1 diabetes treated with antiCD3 monoclonal antibodies Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.Phagocytosis of enterovirus-infected pancreatic beta-cells triggers innate immune responses in human dendritic cells.Immunotherapy of type 1 diabetes: where are we and where should we be going?Germinal centre frequency is decreased in pancreatic lymph nodes from individuals with recent-onset type 1 diabetes.Naturally arising human CD4 T-cells that recognize islet autoantigens and secrete interleukin-10 regulate proinflammatory T-cell responses via linked suppression PTBP1 is required for glucose-stimulated cap-independent translation of insulin granule proteins and Coxsackieviruses in beta cells The Environmental Determinants of Diabetes in the Young (TEDDY) Study.α1-Antitrypsin therapy downregulates toll-like receptor-induced IL-1β responses in monocytes and myeloid dendritic cells and may improve islet function in recently diagnosed patients with type 1 diabetes.The role of innate immune pathways in type 1 diabetes pathogenesis.Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein Bim.Evaluation of RT-PCR and immunohistochemistry as tools for detection of enterovirus in the human pancreas and islets of Langerhans.Coxsackievirus B4 myocarditis and meningoencephalitis in newborn twins.

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Coxsackie B4 virus infection of beta cells and natural killer cell insulitis in recent-onset type 1 diabetic patients.

http://www.wikidata.org/entity/Q35691070

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Proceedings of the National Academy of Sciences of the United States of America

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Coxsackie B4 virus infection o ...... nset type 1 diabetic patients.

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Antonello Covacci

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Astrid G S van Halteren

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Bart O Roep

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Franco Mosca

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John F Elliott

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Matilde Masini

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Sabrina Dionisi

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Stefano Censini

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Ugo Boggi

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P2860

The rise of childhood type 1 diabetes in the 20th century.

Autoreactive CD8 T cells associated with beta cell destruction in type 1 diabetes

Type 1 diabetes: new perspectives on disease pathogenesis and treatment.

Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes.

Regulation of virally induced autoimmunity and immunopathology: contribution of LCMV transgenic models to understanding autoimmune insulin-dependent diabetes mellitus.

Cytomegalovirus in autoimmunity: T cell crossreactivity to viral antigen and autoantigen glutamic acid decarboxylase

Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health

Interferon-gamma is essential for destruction of beta cells and development of insulin-dependent diabetes mellitus.

Isolation of a virus from the pancreas of a child with diabetic ketoacidosis.

Target cell defense prevents the development of diabetes after viral infection.

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5115-5120

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10.1073/PNAS.0700442104

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12

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104

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Piero Marchetti

Stefano Del Prato

Lorella Marselli

Francesco Dotta

Andrea Onetti Muda

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2007-03-14T00:00:00Z

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6447555

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17360338

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1829272

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