The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells
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Adaptive resistance to targeted therapies in cancerRegulation of AU-Rich Element RNA Binding Proteins by Phosphorylation and the Prolyl Isomerase Pin1microRNAs and RNA-binding proteins: a complex network of interactions and reciprocal regulations in cancerRNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma.Cancer stem cell marker Musashi-1 rs2522137 genotype is associated with an increased risk of lung cancer.The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro.RNA binding protein HuR regulates the expression of ABCA1.Overexpression of Musashi-1 protein is associated with progression and poor prognosis of gastric cancer.Intestinal epithelial HuR modulates distinct pathways of proliferation and apoptosis and attenuates small intestinal and colonic tumor developmentELAVL1 modulates transcriptome-wide miRNA binding in murine macrophagesThe role of HuR in the post-transcriptional regulation of interleukin-3 in T cells.Identification and validation of novel small molecule disruptors of HuR-mRNA interaction.Identification of Small-Molecule Inhibitors of the HuR/RNA Interaction Using a Fluorescence Polarization Screening Assay Followed by NMR ValidationTumor suppressive microRNA-137 negatively regulates Musashi-1 and colorectal cancer progression.A Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and StemnessNEAT1 is Required for Survival of Breast Cancer Cells Through FUS and miR-548.Functional genomics analyses of RNA-binding proteins reveal the splicing regulator SNRPB as an oncogenic candidate in glioblastoma.Musashi1 as a potential therapeutic target and diagnostic marker for lung cancerGenomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells.Clinical significance of HuR expression in human malignancy.The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis.Hu Antigen R (HuR) multimerization contributes to glioma disease progression.Musashi1 Impacts Radio-Resistance in Glioblastoma by Controlling DNA-Protein Kinase Catalytic Subunit.miR-761 inhibits tumor progression by targeting MSI1 in ovarian carcinoma.Regulation of Stem Cell Self-Renewal and Oncogenesis by RNA-Binding Proteins.RNA processing as an alternative route to attack glioblastoma.HuR-targeted small molecule inhibitor exhibits cytotoxicity towards human lung cancer cells.Handshakes and Fights: The Regulatory Interplay of RNA-Binding Proteins.RNA Binding Protein as an Emerging Therapeutic Target for Cancer Prevention and Treatment.MicroRNA-195 acts as an anti-proliferative miRNA in human melanoma cells by targeting Prohibitin 1.
P2860
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P2860
The oncogenic RNA-binding protein Musashi1 is regulated by HuR via mRNA translation and stability in glioblastoma cells
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
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2012年论文
@zh-cn
name
The oncogenic RNA-binding prot ...... tability in glioblastoma cells
@ast
The oncogenic RNA-binding prot ...... tability in glioblastoma cells
@en
type
label
The oncogenic RNA-binding prot ...... tability in glioblastoma cells
@ast
The oncogenic RNA-binding prot ...... tability in glioblastoma cells
@en
prefLabel
The oncogenic RNA-binding prot ...... tability in glioblastoma cells
@ast
The oncogenic RNA-binding prot ...... tability in glioblastoma cells
@en
P2093
P2860
P1476
The oncogenic RNA-binding prot ...... tability in glioblastoma cells
@en
P2093
Andrew J Brenner
Björn Scheffler
Daniel Trageser
Jennifer L Martindale
Jonathan A L Gelfond
Kumiko Tominaga
Luiz O F Penalva
Tarea L Burton
P2860
P304
P356
10.1158/1541-7786.MCR-11-0208
P577
2012-01-01T00:00:00Z