The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis.
about
RNA-Binding Protein Musashi1 Is a Central Regulator of Adhesion Pathways in Glioblastoma.Similarity on neural stem cells and brain tumor stem cells in transgenic brain tumor mouse models.Multi-disciplinary methods to define RNA-protein interactions and regulatory networksA conserved three-nucleotide core motif defines Musashi RNA binding specificityID3 contributes to cerebrospinal fluid seeding and poor prognosis in medulloblastoma.Msi1 promotes tumor growth and cell proliferation by targeting cell cycle checkpoint proteins p21, p27 and p53 in cervical carcinomasNeural stem and progenitor cell fate transition requires regulation of Musashi1 function.Computational challenges, tools, and resources for analyzing co- and post-transcriptional events in high throughput.Musashi-2 Silencing Exerts Potent Activity against Acute Myeloid Leukemia and Enhances Chemosensitivity to DaunorubicinA Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and StemnessThe RNA-Binding Protein Musashi1: A Major Player in Intestinal Epithelium Renewal and Colon Cancer Development.Musashi1 as a potential therapeutic target and diagnostic marker for lung cancerMusashi mediates translational repression of the Drosophila hypoxia inducible factor.HuR-regulated mRNAs associated with nuclear hnRNP A1-RNP complexes.Genomic analyses reveal broad impact of miR-137 on genes associated with malignant transformation and neuronal differentiation in glioblastoma cells.RNA binding protein-mediated post-transcriptional gene regulation in medulloblastoma.Discovery of protein-RNA networks.High throughput platform to explore RNA-protein interactomes.Characterization of novel biomarkers in selecting for subtype specific medulloblastoma phenotypes.miR-761 inhibits tumor progression by targeting MSI1 in ovarian carcinoma.Establishment of a novel human medulloblastoma cell line characterized by highly aggressive stem-like cells.Regulation of Stem Cell Self-Renewal and Oncogenesis by RNA-Binding Proteins.Musashi RNA-Binding Proteins as Cancer Drivers and Novel Therapeutic Targets.Musashi-1 Enhances Glioblastoma Cell Migration and Cytoskeletal Dynamics through Translational Inhibition of Tensin3.Knockdown of MSI1 inhibited the cell proliferation of human osteosarcoma cells by targeting p21 and p27.Structural Insight into the Recognition of r(UAG) by Musashi-1 RBD2, and Construction of a Model of Musashi-1 RBD1-2 Bound to the Minimum Target RNA.Musashi1 regulates survival of hepatoma cell lines by activation of Wnt signalling pathway.
P2860
Q30316434-8256CE65-D314-4275-A492-C47A9E378D6DQ34095200-797FEF10-9948-4AAB-B556-D49BF1B54C6BQ34604891-17A5AD63-17EF-4374-A585-72CC63624F77Q34738044-27EA10C8-ED5A-4516-A739-061BA4B0A7EDQ34773836-BB20C645-8EE9-4EB5-8883-3DAE1668B837Q34786587-EC9EF350-F035-437D-8D39-0AC4DCA7CD6EQ35206740-31684B6F-27CA-4701-B401-444C49C2B315Q35417365-516306B0-B746-4F1B-AB3F-A033D618EA96Q35755864-D43A1E8B-D12F-4589-A5B4-41AAE8B4405CQ36463958-E33A239E-BB35-48CF-8AB8-9574CB10BEFEQ37058165-90A5A938-BD7C-4B2F-8CBE-15ED5946CB62Q37093544-8C3F688D-3871-48C0-8D4B-C584B4E610B7Q37264305-BDBD2DF9-2A27-48AF-BE84-12C0EB7BA242Q37291269-2A4077D3-5FC6-45F0-AC0E-2B59FFDDB567Q37505070-8F4B61A5-B051-4573-BC1D-6279E6492231Q38194436-E8A826AA-AB45-4583-9E50-9E151208694EQ38206410-89714E9E-987B-40A2-BD6D-21BC8795FC0CQ38229626-5FA707CF-FAA3-4D64-927D-872DC5F197B1Q38673687-FBD42BF3-92EE-4E8B-8D02-3CAF834A0F3FQ38819843-75834595-1FD3-4E07-8AF7-C6869857D527Q38836198-055B42C9-5BCE-40DB-B57B-039FF1085C18Q38852157-8BF92A1D-DB04-4098-8411-BC148354C07BQ39112430-7D20ED84-76E2-4832-91B0-B5338FDA9DE6Q41459688-D7A2EC5A-4CBF-4E9C-ADA1-D28482A9D2D4Q44964663-06288909-A56D-4A9C-8C4A-724EB81AF10FQ48016360-8AAD3A5E-EE47-4DD1-A993-0FBCC01C06B6Q53071847-76417217-A1C0-42BF-9219-635990F7F445
P2860
The RNA-binding protein Musashi1 affects medulloblastoma growth via a network of cancer-related genes and is an indicator of poor prognosis.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
The RNA-binding protein Musash ...... n indicator of poor prognosis.
@en
type
label
The RNA-binding protein Musash ...... n indicator of poor prognosis.
@en
prefLabel
The RNA-binding protein Musash ...... n indicator of poor prognosis.
@en
P2093
P2860
P50
P1476
The RNA-binding protein Musash ...... n indicator of poor prognosis.
@en
P2093
Adrian M Dubuc
Andrey Korshunov
Dharmalingam Subramaniam
Jonathan A Gelfond
Luiz O F Penalva
Michael D Taylor
Paul A Northcott
Philip J Uren
P2860
P304
P356
10.1016/J.AJPATH.2012.07.031
P407
P577
2012-09-14T00:00:00Z