about
RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genesMT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell developmentThe molecular profile of adult T-cell acute lymphoblastic leukemia: mutations in RUNX1 and DNMT3A are associated with poor prognosis in T-ALL.Notch1 intracellular domain increases cytoplasmic EZH2 levels during early megakaryopoiesis.A simple model system enabling human CD34(+) cells to undertake differentiation towards T cellsJagged-1 signaling suppresses the IL-6 and TGF-β treatment-induced Th17 cell differentiation via the reduction of RORγt/IL-17A/IL-17F/IL-23a/IL-12rb1Emerging molecular targets for the treatment of pre-eclampsia.Notch signaling regulates mouse and human Th17 differentiation.T cells develop normally in the absence of both Deltex1 and Deltex2Genome-wide analyses identify KLF4 as an important negative regulator in T-cell acute lymphoblastic leukemia through directly inhibiting T-cell associated genes.The zebrafish reveals dependence of the mast cell lineage on Notch signaling in vivo.Notch: a unique therapeutic target for immunomodulation.Protease inhibitors as potential disease-modifying therapeutics for Alzheimer's disease.TCR and Notch signaling in CD4 and CD8 T-cell development.Notch signaling and its integration with other signaling mechanisms.Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRENotch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.Novel targeted drug therapies for the treatment of childhood acute leukemiaNotch-induced E2A degradation requires CHIP and Hsc70 as novel facilitators of ubiquitination.Notch signaling specifies megakaryocyte development from hematopoietic stem cells.New Approaches to Target T-ALL.Discovery of SCH 900229, a Potent Presenilin 1 Selective γ-Secretase Inhibitor for the Treatment of Alzheimer's Disease.Regulation of lymphocyte development by cell-type-specific interpretation of Notch signals.gamma-Secretase inhibitor reduces diet-induced atherosclerosis in apolipoprotein E-deficient mice.Pediatric T- and NK-cell lymphomas: new biologic insights and treatment strategies.Loss of CD44dim Expression from Early Progenitor Cells Marks T-Cell Lineage Commitment in the Human ThymusIdentification of Domains for Efficient Notch Signaling Activity in Immobilized Notch Ligand Proteins.Human plasmacytoid dendritic cells from patients with chronic hepatitis B virus infection induce the generation of a higher proportion of CD4(+) and CD25(+) regulatory T cells compared with healthy patients.Human peripheral blood lymphocytes and fibroblasts as Notch3 expression models.Redundancy and cooperation in Notch intercellular signaling.Pivotal role of Notch signaling in regulation of erythroid maturation and proliferation.The role of Notch and IL-7 signaling in early thymocyte proliferation and differentiation.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Notch signaling in T- and B-cell development.
@ast
Notch signaling in T- and B-cell development.
@en
type
label
Notch signaling in T- and B-cell development.
@ast
Notch signaling in T- and B-cell development.
@en
prefLabel
Notch signaling in T- and B-cell development.
@ast
Notch signaling in T- and B-cell development.
@en
P1476
Notch signaling in T- and B-cell development
@en
P2093
Anne Wilson
H Robson MacDonald
P304
P356
10.1016/J.COI.2004.01.002
P577
2004-04-01T00:00:00Z