Two distinctly regulated events, priming and triggering, during retinoid-induced maturation and resistance of NB4 promyelocytic leukemia cell line.
about
Identification and characterization of a leukocyte-specific component of the nuclear bodyRetinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiationInteraction Between Mevalonate Pathway and Retinoic Acid-Induced DifferentiationMechanisms of action and resistance to all-trans retinoic acid (ATRA) and arsenic trioxide (As2O 3) in acute promyelocytic leukemia.Signal transduction and white cell maturation via extracellular ATP and the P2Y11 receptorDensity of points clustering, application to transcriptomic data analysis.In vivo activation of cAMP signaling induces growth arrest and differentiation in acute promyelocytic leukemia.All-trans retinoic acid and hematopoietic growth factors regulating the growth and differentiation of blast progenitors in acute promyelocytic leukemia.MicroRNA-181a-mediated downregulation of AC9 protein decreases intracellular cAMP level and inhibits ATRA-induced APL cell differentiation.Catechins induced acute promyelocytic leukemia cell apoptosis and triggered PML-RARĪ± oncoprotein degradation.Orchestration of multiple arrays of signal cross-talk and combinatorial interactions for maturation and cell death: another vision of t(15;17) preleukemic blast and APL-cell maturation.Pathways of retinoic acid- or arsenic trioxide-induced PML/RARalpha catabolism, role of oncogene degradation in disease remission.Maturation sensitive and resistant t(15;17) NB4 cell lines as tools for APL physiopathology: nomenclature of cells and repertory of their known genetic alterations and phenotypes.cFos mediates cAMP-dependent generation of ROS and rescue of maturation program in retinoid-resistant acute promyelocytic leukemia cell line NB4-LR1.The PML-RARalpha fusion protein and targeted therapy for acute promyelocytic leukemia.Acute promyelocytic leukemia: a model of molecular target based therapy.Treatment of acute promyelocytic leukaemia with all-trans retinoic acid and arsenic trioxide: a paradigm of synergistic molecular targeting therapy.Iodinin (1,6-dihydroxyphenazine 5,10-dioxide) from Streptosporangium sp. induces apoptosis selectively in myeloid leukemia cell lines and patient cells.Synergistic decrease of clonal proliferation, induction of differentiation, and apoptosis of acute promyelocytic leukemia cells after combined treatment with novel 20-epi vitamin D3 analogs and 9-cis retinoic acid.All trans retinoic acid and cancer.Cyclic AMP can promote APL progression and protect myeloid leukemia cells against anthracycline-induced apoptosisTranscriptional silencing of the ETS1 oncogene contributes to human granulocytic differentiationRe-expression of DNA methylation-silenced CD44 gene in a resistant NB4 cell line: rescue of CD44-dependent cell death by cAMP.Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance.Cyclooxygenase-1, but not -2, is upregulated in NB4 leukemic cells and human primary promyelocytic blasts during differentiation.PML-RARA-RXR oligomers mediate retinoid and rexinoid/cAMP cross-talk in acute promyelocytic leukemia cell differentiationRetinoic acid receptor alpha and retinoid-X receptor-specific agonists synergistically target telomerase expression and induce tumor cell death.Arsenic enhances the activation of Stat1 by interferon gamma leading to synergistic expression of IRF-1.Rapid induction of cAMP/PKA pathway during retinoic acid-induced acute promyelocytic leukemia cell differentiation.Gene expression profiling during all-trans retinoic acid-induced cell differentiation of acute promyelocytic leukemia cellscAMP induces co-translational modification of proteins in IPC-81 cells.Retinoic acid regulatory pathways, chromosomal translocations, and acute promyelocytic leukemia.Monocytic differentiation of acute promyelocytic leukemia cells in response to 1,25-dihydroxyvitamin D3 is independent of nuclear receptor binding.Opinion: how patients have benefited from mouse models of acute promyelocytic leukaemia.Three novel Bid proteins generated by alternative splicing of the human Bid gene.Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells.
P2860
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P2860
Two distinctly regulated events, priming and triggering, during retinoid-induced maturation and resistance of NB4 promyelocytic leukemia cell line.
description
1994 nĆ® lÅ«n-bĆ»n
@nan
1994幓ć®č«ę
@ja
1994幓č«ę
@yue
1994幓č«ę
@zh-hant
1994幓č«ę
@zh-hk
1994幓č«ę
@zh-mo
1994幓č«ę
@zh-tw
1994幓č®ŗę
@wuu
1994幓č®ŗę
@zh
1994幓č®ŗę
@zh-cn
name
Two distinctly regulated event ...... myelocytic leukemia cell line.
@ast
Two distinctly regulated event ...... myelocytic leukemia cell line.
@en
type
label
Two distinctly regulated event ...... myelocytic leukemia cell line.
@ast
Two distinctly regulated event ...... myelocytic leukemia cell line.
@en
prefLabel
Two distinctly regulated event ...... myelocytic leukemia cell line.
@ast
Two distinctly regulated event ...... myelocytic leukemia cell line.
@en
P2093
P2860
P356
P1476
Two distinctly regulated event ...... myelocytic leukemia cell line.
@en
P2093
Gendron MC
Genieser HG
Jastorff B
P2860
P304
P356
10.1073/PNAS.91.18.8428
P407
P577
1994-08-01T00:00:00Z