SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation.
about
Small ubiquitin-related modifier-1 modification regulates all-trans-retinoic acid-induced differentiation via stabilization of retinoic acid receptor αThe natural chemopreventive agent sulforaphane inhibits STAT5 activityp97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates.Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation.Deubiquitinating enzymes as promising drug targets for infectious diseases.Structure-function analysis indicates that sumoylation modulates DNA-binding activity of STAT1.An electrophoretic mobility shift assay identifies a mechanistically unique inhibitor of protein sumoylation.FLAGS, frequently mutated genes in public exomes.Regulation of T cell receptor complex-mediated signaling by ubiquitin and ubiquitin-like modificationsThe synthetic α-bromo-2',3,4,4'-tetramethoxychalcone (α-Br-TMC) inhibits the JAK/STAT signaling pathway.Genome-wide analyses identify KLF4 as an important negative regulator in T-cell acute lymphoblastic leukemia through directly inhibiting T-cell associated genes.Characterization of the loss of SUMO pathway function on cancer cells and tumor proliferation.Mechanisms of Jak/STAT signaling in immunity and diseaseRegulation of STAT signaling by acetylation.Chronic Inhibition of STAT3/STAT5 in Treatment-Resistant Human Breast Cancer Cell Subtypes: Convergence on the ROS/SUMO Pathway and Its Effects on xCT Expression and System xc- Activity.SUMO-specific protease 1 regulates mitochondrial biogenesis through PGC-1α.Glutamine Triggers Acetylation-Dependent Degradation of Glutamine Synthetase via the Thalidomide Receptor Cereblon.SENP1 deSUMOylates and regulates Pin1 protein activity and cellular functionProtein sumoylation in brain development, neuronal morphology and spinogenesis.STAT5 acetylation: Mechanisms and consequences for immunological control and leukemogenesis.SUMO-specific proteases/isopeptidases: SENPs and beyond.Sumo and the cellular stress response.Deacetylase inhibitors repress STAT5-mediated transcription by interfering with bromodomain and extra-terminal (BET) protein function.The role of JAK-STAT signaling pathway and its regulators in the fate of T helper cells.An acetylation switch regulates SUMO-dependent protein interaction networks.SENP1 regulates IFN-γ-STAT1 signaling through STAT3-SOCS3 negative feedback loop.Acetylation and sumoylation control STAT5 activation antagonistically.Regulation of transcription factors by sumoylation.Src family kinases interfere with dimerization of STAT5A through a phosphotyrosine-SH2 domain interaction.Inhibition of SENP1 induces radiosensitization in lung cancer cells.Interplay between Janus Kinase/Signal Transducer and Activator of Transcription Signaling Activated by Type I Interferons and Viral Antagonism.DeSUMOylation of Gli1 by SENP1 Attenuates Sonic Hedgehog Signaling.Sumoylation in Development and Differentiation.Introduction to Sumoylation.Interferon Independent Non-Canonical STAT Activation and Virus Induced Inflammation.Regulation of T-Cell Signaling by Post-Translational Modifications in Autoimmune Disease.Novel Latency Reversal Agents for HIV-1 Cure.Implications of STAT3 and STAT5 signaling on gene regulation and chromatin remodeling in hematopoietic cancer
P2860
Q24297577-82814101-BB2E-4EBD-8E8F-E0C3A4138CC7Q28539573-CC56ADCA-B1D2-4572-917D-2F74C58E4675Q33556826-FDFB0899-7E2E-4062-A93D-47FF7A41CFE7Q33771155-D52F21D4-006B-4666-9054-BCD558C09022Q33836097-E5C82C20-3AA8-4B7D-8F1B-FC19D937D3FEQ34435881-404FB03A-FEDA-4D91-8FB9-AE3BB2D35C7CQ34678197-43026BD5-FF6D-4486-9795-5D603DD4D695Q34707985-B26FBCBE-B5DF-4F2C-B85D-D78159E45B9AQ34987659-2C66E708-3CB5-4AE0-8AA9-51FDBD46100CQ35111380-CE3F4B47-3027-4C16-956F-5008E59AFCCDQ35150547-D4A24C80-CAE6-4C41-971C-5F594D0B9DDFQ35363897-9F1769E0-B31E-4DEF-9C69-024D860F5998Q35915068-EC093628-D065-4A59-BBA4-64A2B7631B1CQ35998100-F5148C12-0B52-4BE1-9A41-675FB6673343Q36101371-2705B276-8463-4747-9E87-2CCCE2B431C3Q36492834-1A8DCF6C-3D2B-4253-86F7-C671584FE0D2Q36956452-C05F6334-2C24-4D58-8B6E-D6A4CD99CD55Q37281470-8D3B43F3-D7C7-4C06-838C-F0BC79B275C7Q38125942-268DE176-65CE-4F19-AA1F-691AFD51312BQ38177821-7C496E8C-FD38-4EC4-AAC5-A466FA4B2F21Q38260216-CFC4809F-D55C-42C7-8AED-47B0D39161F0Q38535130-0DBAC6A5-2991-47F2-AAEA-843DC47A8DB2Q38900285-61AE9E8F-1DAB-4989-B742-80A08EDC63EEQ39388632-30F1B7BB-93C0-43AF-B84B-93DF12F1991DQ39502343-33D36B27-0C59-47A8-AA93-5EAA019A98CBQ40476483-7D46F1C6-9311-447C-A8B0-0AB30DBE9DE7Q41390061-F9EF9495-A05B-4AD4-B1E2-2F3FEC1DB8F5Q41544794-EE47545C-E95D-4E41-9150-49DA0C7F44E0Q41849009-B62D5423-F94B-423A-A1ED-2D408E8D4F9BQ42002257-D2B076DF-F346-4D0B-8E0E-A840A7A7CCA8Q47221276-84A15CE9-2768-49AD-9798-343FA3C725CDQ50326757-52759D9E-E6D8-4D84-B25C-36844554267FQ50455844-6A7D4758-B4E0-44C8-812E-DAA13071191EQ51137622-C29A9B34-9454-4D69-8DBC-1EC4A7B9A7E3Q52319726-A5839FC9-C4F3-4F2E-9F76-9D3139105A3EQ52689527-EE4E809F-E0CB-488F-B11F-D9CAAF04AAA0Q52816327-61695EA4-11B7-4C12-A421-E0292FE4CDDAQ57174076-3FE7AD95-DD1A-42C3-8A10-91D70913AD52
P2860
SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
SUMO-specific protease 1 is cr ...... egulation of STAT5 activation.
@ast
SUMO-specific protease 1 is cr ...... egulation of STAT5 activation.
@en
type
label
SUMO-specific protease 1 is cr ...... egulation of STAT5 activation.
@ast
SUMO-specific protease 1 is cr ...... egulation of STAT5 activation.
@en
prefLabel
SUMO-specific protease 1 is cr ...... egulation of STAT5 activation.
@ast
SUMO-specific protease 1 is cr ...... egulation of STAT5 activation.
@en
P2093
P2860
P1433
P1476
SUMO-specific protease 1 is cr ...... egulation of STAT5 activation.
@en
P2093
Edward T H Yeh
Feng-Ming Lin
Jinke Cheng
Long-Sheng Lu
Pornpimon Angkasekwinai
Thang Van Nguyen
Y Eugene Chin
P2860
P304
P356
10.1016/J.MOLCEL.2011.12.026
P577
2012-01-01T00:00:00Z