about
Identification of two novel transmembrane gamma-carboxyglutamic acid proteins expressed broadly in fetal and adult tissuesThe vitamin K oxidoreductase is a multimer that efficiently reduces vitamin K epoxide to hydroquinone to allow vitamin K-dependent protein carboxylationMutations in the GGCX and ABCC6 genes in a family with pseudoxanthoma elasticum-like phenotypes.Investigation and identification of protein γ-glutamyl carboxylation sites.Liver-specific γ-glutamyl carboxylase-deficient mice display bleeding diathesis and short life span.Compound heterozygosity of novel missense mutations in the gamma-glutamyl-carboxylase gene causes hereditary combined vitamin K-dependent coagulation factor deficiencyVitamin K oxygenation, glutamate carboxylation, and processivity: defining the three critical facets of catalysis by the vitamin K-dependent carboxylaseA conformational investigation of propeptide binding to the integral membrane protein γ-glutamyl carboxylase using nanodisc hydrogen exchange mass spectrometry.Methylation of γ-carboxylated Glu (Gla) allows detection by liquid chromatography-mass spectrometry and the identification of Gla residues in the γ-glutamyl carboxylase.r-VKORC1 expression in factor IX BHK cells increases the extent of factor IX carboxylation but is limited by saturation of another carboxylation component or by a shift in the rate-limiting step.Identification of sequences within the gamma-carboxylase that represent a novel contact site with vitamin K-dependent proteins and that are required for activity.Carboxylator: incorporating solvent-accessible surface area for identifying protein carboxylation sites.VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.
P2860
Q24290813-CBEDB8A1-5A37-417B-A72F-0566E5608A2CQ28115117-AFEB8AFA-F3C2-43F4-8FB1-20E0570BCC83Q33979143-ADB86685-9486-4A53-82AF-3B569C09C863Q34174956-6F731B82-5F5B-4292-A11E-0DD8365158F5Q35092888-213358E2-7FAF-4109-AF98-5B3282F2B9F5Q35849078-E788F4D8-6FB4-4F66-91CF-459FDE34EEE2Q36828708-94EFB83A-16FE-49C2-82A6-1D52ED3B2515Q38569603-28D9F52D-7262-4FA1-A686-FB91EC76C1DEQ39358254-6388CD3A-6336-42AC-8E91-0B0012178E96Q40288458-26E6DB0D-5F9A-4340-9C00-433B2CCF0616Q40776115-A1948804-FDD8-4330-8441-A5EF0EB85F6EQ44064526-FABB90BC-C559-4FDC-9FDF-CFA5D5FC5FEBQ50101823-3F58376A-CC9A-4CB4-8B87-709060DDEF72
P2860
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Vitamin K-dependent carboxylation of the carboxylase.
@ast
Vitamin K-dependent carboxylation of the carboxylase.
@en
type
label
Vitamin K-dependent carboxylation of the carboxylase.
@ast
Vitamin K-dependent carboxylation of the carboxylase.
@en
prefLabel
Vitamin K-dependent carboxylation of the carboxylase.
@ast
Vitamin K-dependent carboxylation of the carboxylase.
@en
P2860
P356
P1476
Vitamin K-dependent carboxylation of the carboxylase.
@en
P2093
B N Pudota
K L Berkner
P2860
P304
P356
10.1073/PNAS.95.2.466
P407
P577
1998-01-01T00:00:00Z