The propeptide of rat bone gamma-carboxyglutamic acid protein shares homology with other vitamin K-dependent protein precursors
about
BGLAP is expressed in pancreatic cancer cells and increases their growth and invasionNucleotide sequence of the gene coding for human factor VII, a vitamin K-dependent protein participating in blood coagulationIsolation and molecular cloning of a novel bone phosphoprotein related in sequence to the cystatin family of thiol protease inhibitorsGamma-carboxyglutamate-containing proteins and the vitamin K-dependent carboxylaseExpression of a human proprotein processing enzyme: correct cleavage of the von Willebrand factor precursor at a paired basic amino acid siteMolecular cloning of matrix Gla protein: implications for substrate recognition by the vitamin K-dependent gamma-carboxylaseStructural and functional insights into enzymes of the vitamin K cycleModification of the N-terminus of human factor IX by defective propeptide cleavage or acetylation results in a destabilized calcium-induced conformation: effects on phospholipid binding and activation by factor XIaProcessive post-translational modification. Vitamin K-dependent carboxylation of a peptide substrateHereditary deficiency of all vitamin K-dependent procoagulants and anticoagulantsCloning and sequence analysis of rat bone sialoprotein (osteopontin) cDNA reveals an Arg-Gly-Asp cell-binding sequenceOn a potential global role for vitamin K-dependent gamma-carboxylation in animal systems. Evidence for a gamma-glutamyl carboxylase in Drosophila.trans-10,cis-12 CLA promotes osteoblastogenesis via SMAD mediated mechanism in bone marrow mesenchymal stem cells.Investigation and identification of protein γ-glutamyl carboxylation sites.The first gamma-carboxyglutamic acid-containing contryphan. A selective L-type calcium ion channel blocker isolated from the venom of Conus marmoreus.Cloning and characterization of human liver cDNA encoding a protein S precursor.Vitamin K-dependent carboxylase: possible role of the substrate "propeptide" as an intracellular recognition siteVitamin K-dependent carboxylation of the carboxylase.trans-10,cis-12 conjugated linoleic acid promotes bone formation by inhibiting adipogenesis by peroxisome proliferator activated receptor-γ-dependent mechanisms and by directly enhancing osteoblastogenesis from bone marrow mesenchymal stem cells.Expression of bovine vitamin K-dependent carboxylase activity in baculovirus-infected insect cells.Purification and identification of bovine liver gamma-carboxylaseA mutation in the propeptide of Factor IX leads to warfarin sensitivity by a novel mechanism.Molecular basis of hemophilia B: a defective enzyme due to an unprocessed propeptide is caused by a point mutation in the factor IX precursorIdentification and purification to near homogeneity of the vitamin K-dependent carboxylase.Molecular basis of gamma-carboxylation. Role of the propeptide in the vitamin K-dependent proteins.Osteogenic activity of bone marrow-derived mesenchymal stem cells (BMSCs) seeded on irradiated allogenic bone.A conformational investigation of propeptide binding to the integral membrane protein γ-glutamyl carboxylase using nanodisc hydrogen exchange mass spectrometry.Gla-containing proteins of bone.Functional expression of the human coagulation factor IX using heterologous signal peptide and propeptide sequences in mammalian cell line.Functional Study of the Vitamin K Cycle Enzymes in Live Cells.The propeptide region of clotting factor IX is a signal for a vitamin K dependent carboxylase: evidence from protein engineering of amino acid -4.The cDNA and derived amino acid sequences of human and bovine bone Gla protein.Expression of dentin sialoprotein (DSP) and other molecular determinants by a new cell line from dental papillae, MDPC-23.Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones.Group D prothrombin activators from snake venom are structural homologues of mammalian blood coagulation factor Xa.No evidence for vitamin K-dependent carboxylation of canine surfactant apoproteins, 28-36 kDaDietary phylloquinone intakes and metabolic syndrome in US young adults.Carboxylator: incorporating solvent-accessible surface area for identifying protein carboxylation sites.Defective propeptide processing and abnormal activation underlie the molecular pathology of factor IX Troed-y-Rhiw.Proprotein convertase furin regulates osteocalcin and bone endocrine function.
P2860
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P2860
The propeptide of rat bone gamma-carboxyglutamic acid protein shares homology with other vitamin K-dependent protein precursors
description
1985 nî lūn-bûn
@nan
1985年の論文
@ja
1985年学术文章
@wuu
1985年学术文章
@zh-cn
1985年学术文章
@zh-hans
1985年学术文章
@zh-my
1985年学术文章
@zh-sg
1985年學術文章
@yue
1985年學術文章
@zh
1985年學術文章
@zh-hant
name
The propeptide of rat bone gam ...... K-dependent protein precursors
@ast
The propeptide of rat bone gam ...... K-dependent protein precursors
@en
type
label
The propeptide of rat bone gam ...... K-dependent protein precursors
@ast
The propeptide of rat bone gam ...... K-dependent protein precursors
@en
prefLabel
The propeptide of rat bone gam ...... K-dependent protein precursors
@ast
The propeptide of rat bone gam ...... K-dependent protein precursors
@en
P2860
P356
P1476
The propeptide of rat bone gam ...... K-dependent protein precursors
@en
P2093
P2860
P304
P356
10.1073/PNAS.82.18.6109
P407
P577
1985-09-01T00:00:00Z