Nonhistone protein acetylation as cancer therapy targets. - Wikidata - awgldk - TriplyDB

Nonhistone protein acetylation as cancer therapy targets.

Nonhistone protein acetylation as cancer therapy targets.

http://www.wikidata.org/entity/Q35739676

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Genealogy of an ancient protein family: the Sirtuins, a family of disordered members Structure and Functional Diversity of GCN5-Related N-Acetyltransferases (GNAT)Dynamic Protein Acetylation in Plant-Pathogen Interactions Epigenome engineering in cancer: fairytale or a realistic path to the clinic?Rewriting the epigenetic code for tumor resensitization: a review.Signalling scaffolds and local organization of cellular behaviour PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death B1, a novel HDAC inhibitor, induces apoptosis through the regulation of STAT3 and NF-κB.Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications Histone deacetylase 3 as a novel therapeutic target in multiple myeloma.Effects of ethylene glycol monomethyl ether and its metabolite, 2-methoxyacetic acid, on organogenesis stage mouse limbs in vitro Blocking the class I histone deacetylase ameliorates renal fibrosis and inhibits renal fibroblast activation via modulating TGF-beta and EGFR signaling Use of epigenetic drugs in disease: an overview.Episensitization: therapeutic tumor resensitization by epigenetic agents: a review and reassessment.Syntheses and discovery of a novel class of cinnamic hydroxamates as histone deacetylase inhibitors by multimodality molecular imaging in living subjects.Antioxidants impair anti-tumoral effects of Vorinostat, but not anti-neoplastic effects of Vorinostat and caspase-8 downregulation Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents.Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial-mesenchymal transition.Acetate supplementation as a means of inducing glioblastoma stem-like cell growth arrest Metabolism as a key to histone deacetylase inhibition.Targeting Histone Deacetylases in Diseases: Where Are We?High-throughput small molecule screen identifies inhibitors of aberrant chromatin accessibility.Vorinostat enhances the cisplatin-mediated anticancer effects in small cell lung cancer cells.Systematic analysis of the lysine acetylome in Fusarium graminearum Histone deacetylase inhibitors prevent pulmonary endothelial hyperpermeability and acute lung injury by regulating heat shock protein 90 function.Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation Extracellularly secreted APE1/Ref-1 triggers apoptosis in triple-negative breast cancer cells via RAGE binding, which is mediated through acetylation.Epigenetic Editing: targeted rewriting of epigenetic marks to modulate expression of selected target genes.Energetically unfavorable amide conformations for N6-acetyllysine side chains in refined protein structures.Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer.Molecular and cellular effects of a novel hydroxamate-based HDAC inhibitor - belinostat - in glioblastoma cell lines: a preliminary report.Oncogenic microtubule hyperacetylation through BEX4-mediated sirtuin 2 inhibition.Osterix acetylation at K307 and K312 enhances its transcriptional activity and is required for osteoblast differentiation.HDAC10 promotes lung cancer proliferation via AKT phosphorylation.SAHA, an HDAC inhibitor, synergizes with tacrolimus to prevent murine cardiac allograft rejection.Clinical development of panobinostat in classical Hodgkin's lymphoma.Romidepsin: a novel histone deacetylase inhibitor for cancer.Epigenetics and blood disorders.Histone mimics: digging down under.Genetic and molecular targets in lymphoma: implications for prognosis and treatment.

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P2860

Nonhistone protein acetylation as cancer therapy targets.

http://www.wikidata.org/entity/Q35739676

description

2010 nî lūn-bûn

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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2010年论文

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2010年论文

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name

Nonhistone protein acetylation as cancer therapy targets.

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Nonhistone protein acetylation as cancer therapy targets.

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Nonhistone protein acetylation as cancer therapy targets.

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Nonhistone protein acetylation as cancer therapy targets.

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Nonhistone protein acetylation as cancer therapy targets.

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Expert Review of Anticancer Therapy

P1476

Nonhistone protein acetylation as cancer therapy targets.

@en

P2093

Brahma N Singh

http://www.w3.org/2001/XMLSchema#string

Guanghua Zhang

http://www.w3.org/2001/XMLSchema#string

Jinping Li

http://www.w3.org/2001/XMLSchema#string

Sean C Dowdy

http://www.w3.org/2001/XMLSchema#string

Shi-Wen Jiang

http://www.w3.org/2001/XMLSchema#string

Yi L Hwa

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P2860

The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases

Histone deacetylases specifically down-regulate p53-dependent gene activation

Regulation of histone deacetylase 4 and 5 and transcriptional activity by 14-3-3-dependent cellular localization

Negative control of p53 by Sir2alpha promotes cell survival under stress

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.

Acetylation-dependent signal transduction for type I interferon receptor

The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase

HDAC6 is a microtubule-associated deacetylase

DNA-damage-responsive acetylation of pRb regulates binding to E2F-1

Sirtuin functions in health and disease

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935-954

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10.1586/ERA.10.62

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6

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10

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20553216

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3273412

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