The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
about
Sirtuins: Sir2-related NAD-dependent protein deacetylasesSIRT2 as a Therapeutic Target for Age-Related DisordersThe p68 and p72 DEAD box RNA helicases interact with HDAC1 and repress transcription in a promoter-specific mannerThe flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylasesIdentification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylasesSIRT2 regulates tumour hypoxia response by promoting HIF-1α hydroxylationModulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase.SIRT2 maintains genome integrity and suppresses tumorigenesis through regulating APC/C activityMice lacking α-tubulin acetyltransferase 1 are viable but display α-tubulin acetylation deficiency and dentate gyrus distortionReversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2Myc-nick: a cytoplasmic cleavage product of Myc that promotes alpha-tubulin acetylation and cell differentiationRegulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stressSIRT2 induces the checkpoint kinase BubR1 to increase lifespanMEC-17 is an alpha-tubulin acetyltransferaseA novel GRK2/HDAC6 interaction modulates cell spreading and motilityMitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylationMetabolism, cytoskeleton and cellular signalling in the grip of protein Nepsilon - and O-acetylationNegative regulation of the deacetylase SIRT1 by DBC1A direct interaction between leucine-rich repeat kinase 2 and specific β-tubulin isoforms regulates tubulin acetylationHDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulationEvolutionarily conserved and nonconserved cellular localizations and functions of human SIRT proteinsA role for SIRT2-dependent histone H3K18 deacetylation in bacterial infectionCYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulinSIRT1 regulates the function of the Nijmegen breakage syndrome proteinSirT2 is a histone deacetylase with preference for histone H4 Lys 16 during mitosisInvolvement of SIRT7 in resumption of rDNA transcription at the exit from mitosisThe ATAC acetyl transferase complex controls mitotic progression by targeting non-histone substrates.Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivationThe first identification of lysine malonylation substrates and its regulatory enzymeInterphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosisCrystal structures of human SIRT3 displaying substrate-induced conformational changesSIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activitiesSir-two-homolog 2 (Sirt2) modulates peripheral myelination through polarity protein Par-3/atypical protein kinase C (aPKC) signalingThe dual-specificity phosphatase CDC14B bundles and stabilizes microtubulesMammalian Sir2 homolog SIRT7 is an activator of RNA polymerase I transcriptionSirtuins deacetylate and activate mammalian acetyl-CoA synthetasesChromatin affinity-precipitation using a small metabolic molecule: its application to analysis of O-acetyl-ADP-riboseSynthesis and evaluation of substituted chroman-4-one and chromone derivatives as sirtuin 2-selective inhibitorsEffect of nitroxoline on angiogenesis and growth of human bladder cancerThe chemical complexity of cellular microtubules: tubulin post-translational modification enzymes and their roles in tuning microtubule functions
P2860
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P2860
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
description
2003 nî lūn-bûn
@nan
2003 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@ast
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@en
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@en-gb
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@nl
type
label
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@ast
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@en
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@en-gb
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@nl
prefLabel
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@ast
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@en
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@en-gb
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@nl
P2093
P921
P3181
P1433
P1476
The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase
@en
P2093
Brett L Marshall
Brian J North
John M Denu
Margie T Borra
P304
P3181
P356
10.1016/S1097-2765(03)00038-8
P407
P50
P577
2003-02-01T00:00:00Z