Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.
about
Characterization of MyD118, Gadd45, and proliferating cell nuclear antigen (PCNA) interacting domains. PCNA impedes MyD118 AND Gadd45-mediated negative growth controlTOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinaseHighlight: BRCA1 and BRCA2 proteins in breast cancerIsolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4Cyclin-binding motifs are essential for the function of p21CIP1The mammalian Cut homeodomain protein functions as a cell-cycle-dependent transcriptional repressor which downmodulates p21WAF1/CIP1/SDI1 in S phasePCNA binding proteins in Drosophila melanogaster : the analysis of a conserved PCNA binding domainA conserved domain of the large subunit of replication factor C binds PCNA and acts like a dominant negative inhibitor of DNA replication in mammalian cellsp21Cip1/Waf1 disrupts the recruitment of human Fen1 by proliferating-cell nuclear antigen into the DNA replication complexChromatin-bound PCNA complex formation triggered by DNA damage occurs independent of the ATM gene product in human cellsTransforming growth factor beta stabilizes p15INK4B protein, increases p15INK4B-cdk4 complexes, and inhibits cyclin D1-cdk4 association in human mammary epithelial cellsStudies on the interactions between human replication factor C and human proliferating cell nuclear antigenThe MutSalpha-proliferating cell nuclear antigen interaction in human DNA mismatch repairSuppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigenReciprocal role of cyclins and cyclin kinase inhibitor p21WAF1/CIP1 on lymphocyte proliferation, allo-immune activation and inflammation.PCNA structure and function: insights from structures of PCNA complexes and post-translationally modified PCNAStructure of p15(PAF)-PCNA complex and implications for clamp sliding during DNA replication and repairLagging strand DNA synthesis at the eukaryotic replication fork involves binding and stimulation of FEN-1 by proliferating cell nuclear antigenRequirement of proliferating cell nuclear antigen in RAD6-dependent postreplicational DNA repair.A novel oncostatin M-inducible gene OIG37 forms a gene family with MyD118 and GADD45 and negatively regulates cell growthp15(PAF), a novel PCNA associated factor with increased expression in tumor tissuesDirect interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase deltaTying it all together: epigenetics, genetics, cell cycle, and cancerPCNA binding through a conserved motifA novel function of CRL4(Cdt2): regulation of the subunit structure of DNA polymerase δ in response to DNA damage and during the S phaseThe tail that wags the dog: p12, the smallest subunit of DNA polymerase δ, is degraded by ubiquitin ligases in response to DNA damage and during cell cycle progressionp21(waf) correlates with DNA replication but not with prognosis in invasive breast cancerDifferential activities of the two closely related withanolides, Withaferin A and Withanone: bioinformatics and experimental evidencesAminoimidazole carboxamide ribonucleotide (AICAR) inhibits the growth of retinoblastoma in vivo by decreasing angiogenesis and inducing apoptosisA conserved region in the amino terminus of DNA polymerase delta is involved in proliferating cell nuclear antigen bindingATP-dependent interaction of human mismatch repair proteins and dual role of PCNA in mismatch repairGlobal increase in replication fork speed during a p57KIP2-regulated erythroid cell fate switchProliferating cell nuclear antigen (PCNA): a key factor in DNA replication and cell cycle regulationp21CIP1 mediates reciprocal switching between proliferation and invasion during metastasisInvolvement of DNA-dependent protein kinase in UV-induced replication arrest.Oxidative damage-induced PCNA complex formation is efficient in xeroderma pigmentosum group A but reduced in Cockayne syndrome group B cells.Requirement for PCNA and RPA in interstrand crosslink-induced DNA synthesisPrognostic implications of expression of the cell cycle inhibitor protein p27Kip1.Phosphorylation of p21 in G2/M promotes cyclin B-Cdc2 kinase activity.Cyclin-dependent kinase inhibitor p21 modulates the DNA primer-template recognition complex.
P2860
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P2860
Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
Cdk-interacting protein 1 dire ...... A polymerase delta holoenzyme.
@ast
Cdk-interacting protein 1 dire ...... A polymerase delta holoenzyme.
@en
type
label
Cdk-interacting protein 1 dire ...... A polymerase delta holoenzyme.
@ast
Cdk-interacting protein 1 dire ...... A polymerase delta holoenzyme.
@en
prefLabel
Cdk-interacting protein 1 dire ...... A polymerase delta holoenzyme.
@ast
Cdk-interacting protein 1 dire ...... A polymerase delta holoenzyme.
@en
P2093
P2860
P356
P1476
Cdk-interacting protein 1 dire ...... A polymerase delta holoenzyme.
@en
P2093
H Flores-Rozas
J W Harper
M O'Donnell
S J Elledge
P2860
P304
P356
10.1073/PNAS.91.18.8655
P407
P577
1994-08-01T00:00:00Z