about
Human single-stranded DNA binding proteins are essential for maintaining genomic stabilityORC binding to TRF2 stimulates OriP replicationHigher-order nuclear organization in growth arrest of human mammary epithelial cells: a novel role for telomere-associated protein TIN2POT1 stimulates RecQ helicases WRN and BLM to unwind telomeric DNA substratesRTEL1 maintains genomic stability by suppressing homologous recombinationConserved telomere maintenance component 1 interacts with STN1 and maintains chromosome ends in higher eukaryotesCharacterization of the DNA binding specificity of Shelterin complexesHow the human telomeric proteins TRF1 and TRF2 recognize telomeric DNA: a view from high-resolution crystal structuresPOT1 and TRF2 cooperate to maintain telomeric integrityHuman Rif1, ortholog of a yeast telomeric protein, is regulated by ATM and 53BP1 and functions in the S-phase checkpointVertebrate telomere repeat DNAs favor external loop propeller quadruplex structures in the presence of high concentrations of potassium.Covalent ligation studies on the human telomere quadruplex.Telomere structure and shortening in telomerase-deficient Trypanosoma bruceiRapid generation of long synthetic tandem repeats and its application for analysis in human artificial chromosome formation.Structure and function of the telomeric CST complexInhibition of telomere recombination by inactivation of KEOPS subunit Cgi121 promotes cell longevity.Human LIGIV is synthetically lethal with the loss of Rad54B-dependent recombination and is required for certain chromosome fusion events induced by telomere dysfunctionTranscriptional regulation of telomerase activity: roles of the the Ets transcription factor familyThe role of NBS1 in DNA double strand break repair, telomere stability, and cell cycle checkpoint controlMolecular recognition in complexes of TRF proteins with telomeric DNAThe functional requirement of two structural domains within telomerase RNA emerged early in eukaryotesA balance between elongation and trimming regulates telomere stability in stem cellsRECQL4, the protein mutated in Rothmund-Thomson syndrome, functions in telomere maintenanceThermodynamic characterization of binding Oxytricha nova single strand telomere DNA with the alpha protein N-terminal domain.RTEL1 contributes to DNA replication and repair and telomere maintenance.How telomeres solve the end-protection problem.The genome-wide transcription response to telomerase deficiency in the thermotolerant yeast Hansenula polymorpha DL-1.Fission yeast Taz1 and RPA are synergistically required to prevent rapid telomere lossGenetic variation in five genes important in telomere biology and risk for breast cancer.Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.A role for MRE11, NBS1, and recombination junctions in replication and stable maintenance of EBV episomes.Human POT1 is required for efficient telomere C-rich strand replication in the absence of WRN.Sequence-specific processing of telomeric 3' overhangs by the Werner syndrome protein exonuclease activitySpecific targeting of telomeric multimeric G-quadruplexes by a new triaryl-substituted imidazole.Tankyrase1-mediated poly(ADP-ribosyl)ation of TRF1 maintains cell survival after telomeric DNA damage.Telomeric circles: universal players in telomere maintenance?Human telomeres maintain their overhang length at senescence.Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA.Sex differences in leucocyte telomere length in a free-living mammal.Genome-wide association study of relative telomere length.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
T-loops and the origin of telomeres.
@ast
T-loops and the origin of telomeres.
@en
type
label
T-loops and the origin of telomeres.
@ast
T-loops and the origin of telomeres.
@en
prefLabel
T-loops and the origin of telomeres.
@ast
T-loops and the origin of telomeres.
@en
P356
P1476
T-loops and the origin of telomeres.
@en
P2888
P304
P356
10.1038/NRM1359
P577
2004-04-01T00:00:00Z
P5875
P6179
1010686127