Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.
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Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneRoles of telomeres and telomerase in cancer, and advances in telomerase-targeted therapiesRegulation of the Telomerase Reverse Transcriptase Subunit through Epigenetic MechanismsReactivation of telomerase in cancerVariations in telomere maintenance and the role of telomerase inhibition in gastrointestinal cancerGenetic alterations in hepatocellular carcinoma: An updateFrequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinoma.High prevalence of TERT promoter mutations in primary squamous cell carcinoma of the urinary bladder.High prevalence of TERT promoter mutations in micropapillary urothelial carcinomaAssociation of telomerase reverse transcriptase promoter mutations with clinicopathological features and prognosis of thyroid cancer: a meta-analysis.Isocitrate dehydrogenase mutations in gliomasSomatic Copy Number Alterations at Oncogenic Loci Show Diverse Correlations with Gene Expression.Co-expression of mitosis-regulating genes contributes to malignant progression and prognosis in oligodendrogliomas.Clinical utility of TERT promoter mutations and ALK rearrangement in thyroid cancer patients with a high prevalence of the BRAF V600E mutation.Low Prevalence of Somatic TERT Promoter Mutations in Classic Papillary Thyroid CarcinomaA novel truncated form of HMGA2 in tumors of the ovaries.Understanding TERT Promoter Mutations: A Common Path to Immortality.The prognostic impact of TERT promoter mutations in glioblastomas is modified by the rs2853669 single nucleotide polymorphism.Genetic landscape of meningioma.Telomere-driven diseases and telomere-targeting therapies.Detection of TERT promoter mutations in primary adenocarcinoma of the urinary bladder.Characterization of immortalized human mammary epithelial cell line HMEC 2.6.Genetic variations in TERC and TERT genes are associated with renal cell carcinoma risk in a Chinese Han population.TERT promoter mutations and prognosis in solitary fibrous tumor.Telomerase reverse transcriptase mutations are independent predictor of disease-free survival in Middle Eastern papillary thyroid cancer.HoxC5 and miR-615-3p target newly evolved genomic regions to repress hTERT and inhibit tumorigenesis.Implication of Gastric Cancer Molecular Genetic Markers in Surgical Practice.Characterization and Impact of TERT Promoter Region Mutations on Clinical Outcome in Renal Cell Carcinoma.Current Perspectives of Telomerase Structure and Function in Eukaryotes with Emerging Views on Telomerase in Human Parasites.Presence of TERT Promoter Mutations is a Secondary Event and Associates with Elongated Telomere Length in Myxoid Liposarcomas.Inherited pancreatic cancer.A polymorphism in the promoter region of PD-L1 serves as a binding-site for SP1 and is associated with PD-L1 overexpression and increased occurrence of gastric cancer.hTERT promoter methylation in meningiomas and central nervous hemangiopericytomas.Mechanisms of human telomerase reverse transcriptase (hTERT) regulation: clinical impacts in cancer.Acquired TERT promoter mutations stimulate TERT transcription in mantle cell lymphoma.Detection of Aberrant TERT Promoter Methylation by Combined Bisulfite Restriction Enzyme Analysis for Cancer Diagnosis.Telomere Maintenance Mechanisms in Cancer.AAV9-mediated telomerase activation does not accelerate tumorigenesis in the context of oncogenic K-Ras-induced lung cancerEmerging Medical Treatments for Meningioma in the Molecular Era
P2860
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P2860
Recurrent TERT promoter mutations identified in a large-scale study of multiple tumour types are associated with increased TERT expression and telomerase activation.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Recurrent TERT promoter mutati ...... ion and telomerase activation.
@ast
Recurrent TERT promoter mutati ...... ion and telomerase activation.
@en
type
label
Recurrent TERT promoter mutati ...... ion and telomerase activation.
@ast
Recurrent TERT promoter mutati ...... ion and telomerase activation.
@en
prefLabel
Recurrent TERT promoter mutati ...... ion and telomerase activation.
@ast
Recurrent TERT promoter mutati ...... ion and telomerase activation.
@en
P2093
P2860
P1476
Recurrent TERT promoter mutati ...... sion and telomerase activation
@en
P2093
Dong-Sheng Huang
Hou-Quan Tao
Hui-Ju Wang
Junbo Liang
Patrick J Killela
P2860
P304
P356
10.1016/J.EJCA.2015.03.010
P577
2015-04-02T00:00:00Z