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Molecular Imaging of Metabolic Reprograming in Mutant IDH CellsEpigenetics of Aging and Alzheimer's Disease: Implications for Pharmacogenomics and Drug ResponseMolecular mechanism of the allosteric regulation of the αγ heterodimer of human NAD-dependent isocitrate dehydrogenase.Oncometabolite D-2-Hydroxyglutarate enhances gene silencing through inhibition of specific H3K36 histone demethylases.IDH1 R132H mutation regulates glioma chemosensitivity through Nrf2 pathway.Rapamycin (mTORC1 inhibitor) reduces the production of lactate and 2-hydroxyglutarate oncometabolites in IDH1 mutant fibrosarcoma cellsTargeting Epigenetic Pathways in the Treatment of Pediatric Diffuse (High Grade) Gliomas.Radiolabeled inhibitors as probes for imaging mutant IDH1 expression in gliomas: Synthesis and preliminary evaluation of labeled butyl-phenyl sulfonamide analogs.The comparison of clinical and biological characteristics between IDH1 and IDH2 mutations in gliomas.Recent advances and future of immunotherapy for glioblastoma.The β and γ subunits play distinct functional roles in the α2βγ heterotetramer of human NAD-dependent isocitrate dehydrogenase.Prognostic and diagnostic potential of isocitrate dehydrogenase 1 in esophageal squamous cell carcinoma.The Glutamate Dehydrogenase Pathway and Its Roles in Cell and Tissue Biology in Health and Disease.The Role of miRNAs in Angiogenesis, Invasion and Metabolism and Their Therapeutic Implications in Gliomas.Biological Significance of Mutant Isocitrate Dehydrogenase 1 and 2 in Gliomagenesis.Vaccine-based immunotherapeutic approaches to gliomas and beyond.An update on the epigenetics of glioblastomas.Metabolic Reprogramming in Glioma.Magnetic Resonance Spectroscopy for Detection of 2-Hydroxyglutarate as a Biomarker for IDH Mutation in Gliomas.Characterization of gliomas: from morphology to molecules.The Enzymology of 2-Hydroxyglutarate, 2-Hydroxyglutaramate and 2-Hydroxysuccinamate and Their Relationship to OncometabolitesEGFR Amplification and IDH Mutations in Glioblastoma Patients of the Northeast of Morocco.Expression patterns of members of the isocitrate dehydrogenase gene family in murine inner ear.The 2016 revision of the WHO Classification of Central Nervous System Tumours: retrospective application to a cohort of diffuse gliomas.Dual-Genotype Diffuse Low-Grade Glioma: Is It Really Time to Abandon Oligoastrocytoma As a Distinct Entity?Adaptive Evolution of the GDH2 Allosteric Domain Promotes Gliomagenesis by Resolving IDH1R132H-Induced Metabolic Liabilities.Synthesis and evaluation of radiolabeled AGI-5198 analogues as candidate radiotracers for imaging mutant IDH1 expression in tumors.Role of Macrophages in Brain Tumor Growth and Progression.The Role for Myc in Coordinating Glycolysis, Oxidative Phosphorylation, Glutaminolysis, and Fatty Acid Metabolism in Normal and Neoplastic Tissues.Metabolic Enzymes in Sarcomagenesis: Progress Toward Biology and Therapy.Heat shock protein peptide complex-96 vaccination for newly diagnosed glioblastoma: a phase I, single-arm trial.Clinical and immunological correlates of long term survival in glioblastoma.Epstein-Barr Virus in Gliomas: Cause, Association, or Artifact?Commentary on "Phase III randomized study of radiation and temozolomide versus radiation and nitrosourea therapy for anaplastic astrocytoma: results of NRG Oncology RTOG 9813".Predictors of Response to Autologous Dendritic Cell Therapy in Glioblastoma Multiforme.Biological Role and Therapeutic Potential of IDH Mutations in Cancer.Glycerophosphatidylcholine PC(36:1) absence and 3'-phosphoadenylate (pAp) accumulation are hallmarks of the human glioma metabolomeLow level of isocitrate dehydrogenase 1 predicts unfavorable postoperative outcomes in patients with clear cell renal cell carcinomaBridging Cancer Biology with the Clinic: Comprehending and Exploiting IDH Gene Mutations in Gliomas
P2860
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P2860
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
Isocitrate dehydrogenase mutations in gliomas
@ast
Isocitrate dehydrogenase mutations in gliomas
@en
type
label
Isocitrate dehydrogenase mutations in gliomas
@ast
Isocitrate dehydrogenase mutations in gliomas
@en
prefLabel
Isocitrate dehydrogenase mutations in gliomas
@ast
Isocitrate dehydrogenase mutations in gliomas
@en
P2860
P356
P1433
P1476
Isocitrate dehydrogenase mutations in gliomas
@en
P2093
Matthew S Waitkus
P2860
P356
10.1093/NEUONC/NOV136
P577
2015-07-16T00:00:00Z