Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.
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Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revisedFocal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice.APP transgenic mice for modelling behavioural and psychological symptoms of dementia (BPSD).Amyloid activates GSK-3beta to aggravate neuronal tauopathy in bigenic mice.Alzheimer disease models and human neuropathology: similarities and differencesA novel Aβ-fibrinogen interaction inhibitor rescues altered thrombosis and cognitive decline in Alzheimer's disease miceAnalysis of cerebral amyloid angiopathy in a transgenic mouse model of Alzheimer disease using in vivo multiphoton microscopy.Characterization of amyloid beta peptides from brain extracts of transgenic mice overexpressing the London mutant of human amyloid precursor protein.Age-related vascular pathology in transgenic mice expressing presenilin 1-associated familial Alzheimer's disease mutations.Genetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathiesRole of vascular risk factors and vascular dysfunction in Alzheimer's disease.Animal models of amyloid-beta-related pathologies in Alzheimer's disease.Cerebral amyloid angiopathy in the elderlyPathological Hallmarks, Clinical Parallels, and Value for Drug Testing in Alzheimer's Disease of the APP[V717I] London Transgenic Mouse Model.Pathogenic effects of cerebral amyloid angiopathy mutations in the amyloid beta-protein precursor.Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis.Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse modelsPhysicochemical characteristics of soluble oligomeric Abeta and their pathologic role in Alzheimer's disease.Cortical and leptomeningeal cerebrovascular amyloid and white matter pathology in Alzheimer's diseaseAutomated detection of amyloid-β-related cortical and subcortical signal changes in a transgenic model of Alzheimer's disease using high-field MRI.Neurodegeneration and neuroinflammation in cdk5/p25-inducible mice: a model for hippocampal sclerosis and neocortical degeneration.Tauopathy differentially affects cell adhesion molecules in mouse brain: early down-regulation of nectin-3 in stratum lacunosum moleculare.Genetic ablation of apolipoprotein A-IV accelerates Alzheimer's disease pathogenesis in a mouse modelNeuronal or glial expression of human apolipoprotein e4 affects parenchymal and vascular amyloid pathology differentially in different brain regions of double- and triple-transgenic miceDense-core plaques in Tg2576 and PSAPP mouse models of Alzheimer's disease are centered on vessel wallsCerebral microvascular amyloid beta protein deposition induces vascular degeneration and neuroinflammation in transgenic mice expressing human vasculotropic mutant amyloid beta precursor protein.Neurovascular function in Alzheimer's disease patients and experimental models.beta-site amyloid precursor protein cleaving enzyme 1 increases amyloid deposition in brain parenchyma but reduces cerebrovascular amyloid angiopathy in aging BACE x APP[V717I] double-transgenic miceVascular β-amyloid and early astrocyte alterations impair cerebrovascular function and cerebral metabolism in transgenic arcAβ mice.Cerebral amyloid angiopathy: pathogenesis and effects on the ageing and Alzheimer brain.Rodent A beta modulates the solubility and distribution of amyloid deposits in transgenic mice.Combined treatment of Aβ immunization with statin in a mouse model of Alzheimer's disease.Prominent axonopathy and disruption of axonal transport in transgenic mice expressing human apolipoprotein E4 in neurons of brain and spinal cord.A Peephole into the Brain: Neuropathological Features of Alzheimer's Disease Revealed by in vivo Two-Photon ImagingTranslating basic science research to clinical application: models and strategies for intracerebral hemorrhage.APOE and cerebral amyloid angiopathy in community-dwelling older persons.Sporadic cerebral amyloid angiopathy: pathology, clinical implications, and possible pathomechanisms.Neurologic and motor dysfunctions in APP transgenic mice.Mechanism of cerebral beta-amyloid angiopathy: murine and cellular models.Delayed amyloid plaque deposition and behavioral deficits in outcrossed AβPP/PS1 mice.
P2860
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P2860
Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Prominent cerebral amyloid ang ...... utant of human APP in neurons.
@ast
Prominent cerebral amyloid ang ...... utant of human APP in neurons.
@en
type
label
Prominent cerebral amyloid ang ...... utant of human APP in neurons.
@ast
Prominent cerebral amyloid ang ...... utant of human APP in neurons.
@en
prefLabel
Prominent cerebral amyloid ang ...... utant of human APP in neurons.
@ast
Prominent cerebral amyloid ang ...... utant of human APP in neurons.
@en
P2093
P2860
P1476
Prominent cerebral amyloid ang ...... mutant of human APP in neurons
@en
P2093
C Van Den Haute
D Moechars
F Van Leuven
H Vanderstichele
I Dewachter
J Van Dorpe
P2860
P304
P356
10.1016/S0002-9440(10)64644-5
P407
P577
2000-10-01T00:00:00Z