Essential Role of Calmodulin in RyR Inhibition by Dantrolene. - Wikidata - awgldk - TriplyDB

Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

http://www.wikidata.org/entity/Q35745969

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Critical Role of Intracellular RyR1 Calcium Release Channels in Skeletal Muscle Function and Disease Calcium Dynamics Mediated by the Endoplasmic/Sarcoplasmic Reticulum and Related Diseases.The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor The emerging role of calmodulin regulation of RyR2 in controlling heart rhythm, the progression of heart failure and the antiarrhythmic action of dantrolene.Pharmacogenetics and pathophysiology of CACNA1S mutations in malignant hyperthermia.CaMKII-dependent phosphorylation of RyR2 promotes targetable pathological RyR2 conformational shift.Successful early application of extracorporeal membrane oxygenation to support cardiopulmonary resuscitation for a patient suffering from severe malignant hyperthermia and cardiac arrest: a case report.In vivo Ca2+ dynamics induced by Ca2+ injection in individual rat skeletal muscle fibers.Organelle membrane derived patches: reshaping classical methods for new targets Dantrolene requires Mg2+ to arrest malignant hyperthermia.EL20, A Potent Antiarrhythmic Compound, Selectively Inhibits Calmodulin Deficient Ryanodine Receptor Type 2.The structural basis of ryanodine receptor ion channel function.Reduced threshold for store overload-induced Ca2+ release is a common defect of RyR1 mutations associated with malignant hyperthermia and central core disease.Repurposing Dantrolene for Long-Term Combination Therapy to Potentiate Antisense-Mediated DMD Exon Skipping in the mdx Mouse.Multidirectional Efficacy of Biologically Active Nitro Compounds Included in Medicines.

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Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

http://www.wikidata.org/entity/Q35745969

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2015 nî lūn-bûn

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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2015年论文

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2015年论文

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Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

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Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

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Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

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Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

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Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

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Molecular Pharmacology

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Essential Role of Calmodulin in RyR Inhibition by Dantrolene.

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Bjorn C Knollmann

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Derek R Laver

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Dirk F van Helden

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Kafa Walweel

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Mohammad S Imtiaz

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Nieves Gomez-Hurtado

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Ye Win Oo

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P2860

Malignant-hyperthermia susceptibility is associated with a mutation of the alpha 1-subunit of the human dihydropyridine-sensitive L-type voltage-dependent calcium-channel receptor in skeletal muscle

Casq2 deletion causes sarcoplasmic reticulum volume increase, premature Ca2+ release, and catecholaminergic polymorphic ventricular tachycardia

FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel

Subconductance activity induced by quinidine and quinidinium in purified cardiac sarcoplasmic reticulum calcium release channels.

Catecholaminergic polymorphic ventricular tachycardia is caused by mutation-linked defective conformational regulation of the ryanodine receptor.

Data transformations for improved display and fitting of single-channel dwell time histograms

The skeletal muscle ryanodine receptor identified as a molecular target of [3H]azidodantrolene by photoaffinity labeling.

Charged local anesthetics block ionic conduction in the sheep cardiac sarcoplasmic reticulum calcium release channel.

Calmodulin activation and inhibition of skeletal muscle Ca2+ release channel (ryanodine receptor)

Regulation of the calcium release channel from skeletal muscle by suramin and the disulfonated stilbene derivatives DIDS, DBDS, and DNDS.

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57-63

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10.1124/MOL.115.097691

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1

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88

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2015-04-28T00:00:00Z

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275662840

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25920678

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