Expression of geminin as a marker of cell proliferation in normal tissues and malignancies.
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Cdt1 associates dynamically with chromatin throughout G1 and recruits Geminin onto chromatinGeminin regulates neuronal differentiation by antagonizing Brg1 activityLoss of rereplication control in Saccharomyces cerevisiae results in extensive DNA damageSelective killing of cancer cells by suppression of geminin activityPreventing re-replication of chromosomal DNA.Prognostic value of proliferation in invasive breast cancer: a reviewHBO1 histone acetylase activity is essential for DNA replication licensing and inhibited by GemininIncreased expression of geminin stimulates the growth of mammary epithelial cells and is a frequent event in human tumorsHBO1 histone acetylase is a coactivator of the replication licensing factor Cdt1A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic ReprogrammingThe APC/C inhibitor, Emi1, is essential for prevention of rereplicationRecruitment of ORC or CDC6 to DNA is sufficient to create an artificial origin of replication in mammalian cellsCdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.A Cdt1-geminin complex licenses chromatin for DNA replication and prevents rereplication during S phase in Xenopus.Oncomodulatory signals by regulatory proteins encoded by human cytomegalovirus: a novel role for viral infection in tumor progression.Geminin overexpression induces mammary tumors via suppressing cytokinesis.Identification of novel cellular targets in biliary tract cancers using global gene expression technology.Characterization of gonadal transcriptomes from the turbot (Scophthalmus maximus).Prognostic significance of Minichromosome maintenance protein 7 and Geminin expression in patients with 109 soft tissue sarcomas.Dynamic interactions of high Cdt1 and geminin levels regulate S phase in early Xenopus embryos.DNA replication licensing and cell cycle kinetics of oligodendroglial tumours.Merkel cell polyomavirus T antigens promote cell proliferation and inflammatory cytokine gene expressionGene discovery in cervical cancer : towards diagnostic and therapeutic biomarkers.Cell-cycle-phase progression analysis identifies unique phenotypes of major prognostic and predictive significance in breast cancerExpression of Mcm2, geminin and Ki67 in normal oral mucosa, oral epithelial dysplasias and their corresponding squamous-cell carcinomasDNA replication licensing factors and aneuploidy are linked to tumor cell cycle state and clinical outcome in penile carcinomaBiomarkers in bladder cancer.S-phase-coupled apoptosis in tumor suppression.Overexpression of the replication licensing regulators hCdt1 and hCdc6 characterizes a subset of non-small-cell lung carcinomas: synergistic effect with mutant p53 on tumor growth and chromosomal instability--evidence of E2F-1 transcriptional controCell cycle regulator geminin is dispensable for the proliferation of vascular smooth muscle cells.Geminin promotes an epithelial-to-mesenchymal transition in an embryonic stem cell model of gastrulation.Contrast-enhanced intraoperative ultrasonography for vascular imaging of hepatocellular carcinoma: clinical and biological significance.Therapeutic targeting and patient selection for cancers with homologous recombination defects.Geminin is overexpressed in human pancreatic cancer and downregulated by the bioflavanoid apigenin in pancreatic cancer cell lines.Geminin cleavage during apoptosis by caspase-3 alters its binding ability to the SWI/SNF subunit Brahma.Cell type-specific responses of human cells to inhibition of replication licensing.Geminin: a good prognostic factor in high-grade astrocytic brain tumors.The potential utility of geminin as a predictive biomarker in breast cancer.The impact of delay in cryo-fixation on biomarkers of Src tyrosine kinase activity in human breast and bladder cancers.Geminin deficiency enhances survival in a murine medulloblastoma model by inducing apoptosis of preneoplastic granule neuron precursors.
P2860
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P2860
Expression of geminin as a marker of cell proliferation in normal tissues and malignancies.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
Expression of geminin as a mar ...... rmal tissues and malignancies.
@ast
Expression of geminin as a mar ...... rmal tissues and malignancies.
@en
type
label
Expression of geminin as a mar ...... rmal tissues and malignancies.
@ast
Expression of geminin as a mar ...... rmal tissues and malignancies.
@en
prefLabel
Expression of geminin as a mar ...... rmal tissues and malignancies.
@ast
Expression of geminin as a mar ...... rmal tissues and malignancies.
@en
P2093
P2860
P1476
Expression of geminin as a mar ...... rmal tissues and malignancies.
@en
P2093
Andrew P Weng
James A Wohlschlegel
Jeffery L Kutok
P2860
P304
P356
10.1016/S0002-9440(10)64178-8
P407
P577
2002-07-01T00:00:00Z