Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53. - Wikidata - awgldk - TriplyDB

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

http://www.wikidata.org/entity/Q34464170

about

Characterization and structure determination of the Cdt1 binding domain of human minichromosome maintenance (Mcm) 6 Prevention of DNA re-replication in eukaryotic cells Replication licensing and cancer--a fatal entanglement?Mechanisms to control rereplication and implications for cancer.DNA damage induces Cdt1 proteolysis in fission yeast through a pathway dependent on Cdt2 and Ddb1 Re-replication of a centromere induces chromosomal instability and aneuploidy Differences in the DNA replication of unicellular eukaryotes and metazoans: known unknowns Regulation and Function of Cdt1; A Key Factor in Cell Proliferation and Genome Stability Replication fork instability and the consequences of fork collisions from rereplication Chromatin unfolding by Cdt1 regulates MCM loading via opposing functions of HBO1 and HDAC11-geminin.Structural insights into the Cdt1-mediated MCM2-7 chromatin loading.Specific replication origins promote DNA amplification in fission yeast.Cdt1 is differentially targeted for degradation by anticancer chemotherapeutic drugs.Cell type-dependent requirement for PIP box-regulated Cdt1 destruction during S phase.Homologous recombination is a primary pathway to repair DNA double-strand breaks generated during DNA rereplication Single-stranded annealing induced by re-initiation of replication origins provides a novel and efficient mechanism for generating copy number expansion via non-allelic homologous recombination.Cdt1 revisited: complex and tight regulation during the cell cycle and consequences of deregulation in mammalian cells.Regulatory mechanisms that prevent re-initiation of DNA replication can be locally modulated at origins by nearby sequence elements.MINCR is a MYC-induced lncRNA able to modulate MYC's transcriptional network in Burkitt lymphoma cells Replication origins: determinants or consequences of nuclear organization?Repression of nascent strand elongation by deregulated Cdt1 during DNA replication in Xenopus egg extracts.Divergent S phase checkpoint activation arising from prereplicative complex deficiency controls cell survival.Met promotes the formation of double minute chromosomes induced by Sei-1 in NIH-3T3 murine fibroblasts.DNA replication licensing control and rereplication prevention.Quality control in the initiation of eukaryotic DNA replication.CRL Ubiquitin Ligases and DNA Damage Response.Flipping the switch from g1 to s phase with e3 ubiquitin ligases Targeting mitotic pathways for endocrine-related cancer therapeutics.Strategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication.Transcriptional control of DNA replication licensing by Myc.RETRACTED: Glypican 1 stimulates S phase entry and DNA replication in human glioma cells and normal astrocytes.Loss of DNA replication control is a potent inducer of gene amplification.Quantitative expression profiling guided by common retroviral insertion sites reveals novel and cell type specific cancer genes in leukemia.Long noncoding RNA identification in lymphoma.

P2860

Q24301640-B30A112A-63C5-4F60-BF38-22A5DA45CD8A Q24632601-521B0C1D-C7BB-49F4-807F-D02511334F99 Q24644766-A5A4390E-B072-4291-AA09-E98077FD9B17 Q24669595-82D8098A-911E-43C1-B9ED-601284D0A7E5 Q24672982-4D19ED51-44EE-45FF-BB19-9F2A9A5DF675 Q27311421-293191B4-3630-41C9-BEC2-CA4E7A8E78C6 Q27694684-A5AA56CC-976B-4E4C-A9A0-9E31DB6F62BE Q28068574-8C42FF0C-B583-4159-B2A6-B957D6B39413 Q28076969-F97FD481-7700-486C-B635-31C9B7108249 Q30429899-409F005F-9430-4A08-8EC5-39804A7248D2 Q34090656-FB7200E5-3CB1-4D8E-8D39-6618C24D3A91 Q34098424-CB366F7E-5E01-425E-AEEA-8876CB79DF47 Q34222698-8C6AB88C-F396-4173-AC45-824BCB04960E Q34249169-48731594-CBC6-4F5B-8DCC-55E70CB821BA Q34355626-EF266654-1016-48B2-AB38-899B10444B16 Q34539939-514CE25A-337F-426F-BB64-F8B09344D920 Q35107397-7890BDCD-BF0E-4DE9-BF75-7C269FF72881 Q35191354-2D6FDD28-B237-4769-95EF-307CEAC8C130 Q36103110-68097E2E-8D4D-44D7-AA3E-C0E4030FE546 Q37022588-82A3E8B6-7E10-4959-B9E2-BEF42C158B9E Q37078588-A3B03AFC-56A9-40B9-8DFE-9C6E9267E85C Q37327314-DB5B25C5-8409-4134-974C-4F8C869241D1 Q37636683-13D156E5-22C7-44AB-9E12-EE3D27A474D1 Q37825828-9ACED7CC-A03D-41C9-9130-DCB765B1BF4B Q37956282-A768E29D-BE60-4622-910D-825274EEA20F Q38015388-4EB32F7F-4BA3-4A61-96B5-157600ABBB02 Q38103251-0EB2AF5C-FB9D-414A-A2F8-C5F13E8D8426 Q38671036-7493D0A3-2973-48B1-82B5-108434D88DE5 Q38810286-452477EC-0FB1-4DEA-9129-64205B4F689B Q39048077-7AD52E5D-3F98-44D4-A18A-27D17D0FF5DC Q39098101-C9C5F086-7A89-4CD3-89DF-DA9A93598AF6 Q41907614-81EB9163-23E1-442E-A11D-BE33E0B3E20D Q42324329-ACCBFDEE-6AC9-47F4-933D-156C3F37F359 Q47848636-0F316E6C-3C33-4ACF-802C-27ED626775BA

P2860

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

http://www.wikidata.org/entity/Q34464170

description

2005 nî lūn-bûn

@nan

2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2005年の論文

@ja

2005年論文

@yue

2005年論文

@zh-hant

2005年論文

@zh-hk

2005年論文

@zh-mo

2005年論文

@zh-tw

2005年论文

@wuu

name

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

@ast

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

@en

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

@nl

type

label

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

@ast

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

@en

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

@nl

prefLabel

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

@ast

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

@en

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

@nl

P1433

Q34464170-913D1B61-10C1-46BC-B160-3D61F0FABC28

P1476

Q34464170-4AF374A7-4AB7-4F03-B112-12935C1CD630

P2093

Q34464170-2CCBC20B-46F8-4F94-8526-C181B378F416

Q34464170-4BDCB0A8-BB0E-4188-B7E0-798B7B8BEAF9

Q34464170-59DE55BD-B212-4E8D-818C-98DED4FF5034

Q34464170-94D483A7-8408-4559-BBB1-9F3B7A73C2CB

Q34464170-9E00BB87-6BCC-4504-9709-5FE6F9FB1AA5

Q34464170-D9B71886-D18A-4B6F-9A96-3ADE749A5695

Q34464170-F5C6639B-5402-4846-824D-E8E1370970D3

P2860

Q34464170-02550CEC-3596-4286-9A5A-5DD7D00B139B

Q34464170-02A38CA1-AAA8-43E3-A963-8BFE0E79C36D

Q34464170-0DCB4888-7573-43FA-AA14-06A8D9725626

Q34464170-120EDE17-2A94-45EF-B660-2AB2F9CC7F6D

Q34464170-1A3370E7-2AE2-4389-A9FD-B4598BF8D6C8

Q34464170-2BCBD90E-186E-4C1E-8D3E-8E1F26370DDA

Q34464170-39779C2A-4941-4D31-8086-C8E6EB747FF7

Q34464170-49811B8C-C9D9-4CE2-A345-11D03EBA2DC1

Q34464170-4F3E4BE7-BAE7-4475-9ADC-0B4B2E627B4D

Q34464170-55534568-3A95-4219-A24B-B3B7EA018E47

P2888

Q34464170-E8D3F687-5EF4-4BB1-9818-92471C65CB44

P304

Q34464170-2562490D-6090-4CA2-BCFA-5C128720AB0B

P31

Q34464170-B39DF0D2-0E88-4A21-8272-7232EB3ACF61

P356

Q34464170-29FBFA44-6D24-4191-87F9-8086D714E56C

P407

Q34464170-BB6CEB65-502C-49E6-8A71-15902E5636E7

P433

Q34464170-1185A366-395D-4D63-8E16-A0833E101927

P478

Q34464170-34006BD0-1CFE-4C26-8B56-3545786111EC

P577

Q34464170-F6DAE342-5E40-454B-A61D-C419E16929D9

P5875

Q34464170-BBA56F6A-711E-4FB2-8CA0-BC68674E3B0D

P6179

Q34464170-EE4A8DE9-5BF1-4CC9-AEB6-CF71271FAD91

P698

Q34464170-7317A644-A973-4830-AA84-BF7990AA105E

P356

P1433

P1476

Cdt1 transgenic mice develop lymphoblastic lymphoma in the absence of p53.

@en

P2093

Eunpyo Moon

http://www.w3.org/2001/XMLSchema#string

Girdhar G Sharma

http://www.w3.org/2001/XMLSchema#string

Junghee Seo

http://www.w3.org/2001/XMLSchema#string

Kyunghee Choi

http://www.w3.org/2001/XMLSchema#string

Tej K Pandita

http://www.w3.org/2001/XMLSchema#string

Walter R Burack

http://www.w3.org/2001/XMLSchema#string

Yun S Chung

http://www.w3.org/2001/XMLSchema#string

P2860

MCM2--a promising marker for premalignant lesions of the lung: a cohort study

The Hallmarks of Cancer

Inhibition of eukaryotic DNA replication by geminin binding to Cdt1

Rereplication by depletion of geminin is seen regardless of p53 status and activates a G2/M checkpoint

Mutation and cancer: statistical study of retinoblastoma

Loss of Geminin induces rereplication in the presence of functional p53

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis

The Cdt1 protein is required to license DNA for replication in fission yeast

ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex

P2888

P304

8176-8186

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/SJ.ONC.1208881

http://www.w3.org/2001/XMLSchema#string

P407

P433

55

http://www.w3.org/2001/XMLSchema#string

P478

24

http://www.w3.org/2001/XMLSchema#string

P577

2005-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

7506195

http://www.w3.org/2001/XMLSchema#string

P6179

1003472467

http://www.w3.org/2001/XMLSchema#string

P698

16261166

http://www.w3.org/2001/XMLSchema#string