Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex.
about
Ribosomal Protein S6 Phosphorylation in the Nervous System: From Regulation to FunctionCharacterizing autism spectrum disorders by key biochemical pathways.The molecular basis of cognitive deficits in pervasive developmental disordersDendritic spine dysgenesis in autism related disordersThe pathophysiology of fragile X (and what it teaches us about synapses)Altered mGluR5-Homer scaffolds and corticostriatal connectivity in a Shank3 complete knockout model of autism.FMRP targets distinct mRNA sequence elements to regulate protein expressionStriatopallidal dysfunction underlies repetitive behavior in Shank3-deficient model of autism.Excitatory/inhibitory synaptic imbalance leads to hippocampal hyperexcitability in mouse models of tuberous sclerosis.A circuitry and biochemical basis for tuberous sclerosis symptoms: from epilepsy to neurocognitive deficitsEpilepsy and Autism.FMRP S499 is phosphorylated independent of mTORC1-S6K1 activity.Dysregulation of Elongation Factor 1A Expression is Correlated with Synaptic Plasticity Impairments in Alzheimer's Disease.Necessary, but not sufficient: insights into the mechanisms of mGluR mediated long-term depression from a rat model of early life seizuresDysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and AutismMEK-ERK1/2-dependent FLNA overexpression promotes abnormal dendritic patterning in tuberous sclerosis independent of mTOR.Increasing our understanding of human cognition through the study of Fragile X Syndrome.Reduced juvenile long-term depression in tuberous sclerosis complex is mitigated in adults by compensatory recruitment of mGluR5 and Erk signaling.Mapk/Erk activation in an animal model of social deficits shows a possible link to autism.Tuberous Sclerosis: A New Frontier in Targeted Treatment of AutismAutism-Associated Insertion Mutation (InsG) of Shank3 Exon 21 Causes Impaired Synaptic Transmission and Behavioral Deficits.TSC2/mTORC1 signaling controls Paneth and goblet cell differentiation in the intestinal epithelium.Layer specific and general requirements for ERK/MAPK signaling in the developing neocortexSynaptic plasticity and learning in animal models of tuberous sclerosis complex.Cognitive impairment in epilepsy: the role of network abnormalities.Hippocampal metabotropic glutamate receptor long-term depression in health and disease: focus on mitogen-activated protein kinase pathways.Unifying Views of Autism Spectrum Disorders: A Consideration of Autoregulatory Feedback Loops.Initial analysis of peripheral lymphocytic extracellular signal related kinase activation in autism.Mechanisms underlying cognitive deficits in a mouse model for Costello Syndrome are distinct from other RASopathy mouse modelsMale-specific deficits in natural reward learning in a mouse model of neurodevelopmental disorders.Reducing eIF4E-eIF4G interactions restores the balance between protein synthesis and actin dynamics in fragile X syndrome model mice.Roles for Arc in metabotropic glutamate receptor-dependent LTD and synapse elimination: Implications in health and disease.An essential role for UBE2A/HR6A in learning and memory and mGLUR-dependent long-term depression.
P2860
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P2860
Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
Metabotropic glutamate recepto ...... of tuberous sclerosis complex.
@ast
Metabotropic glutamate recepto ...... of tuberous sclerosis complex.
@en
type
label
Metabotropic glutamate recepto ...... of tuberous sclerosis complex.
@ast
Metabotropic glutamate recepto ...... of tuberous sclerosis complex.
@en
prefLabel
Metabotropic glutamate recepto ...... of tuberous sclerosis complex.
@ast
Metabotropic glutamate recepto ...... of tuberous sclerosis complex.
@en
P2093
P2860
P1476
Metabotropic glutamate recepto ...... of tuberous sclerosis complex.
@en
P2093
Aditi Bhattacharya
Areum Kang
Emanuela Santini
Eric Klann
Hanoch Kaphzan
Itzamarie Chévere-Torres
Jack L Arbiser
Jordan M Maki
Michael J Gambello
P2860
P304
P356
10.1016/J.NBD.2011.12.028
P577
2011-12-16T00:00:00Z