Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency
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Diabetes Mellitus Induces Alzheimer's Disease Pathology: Histopathological Evidence from Animal ModelsThe roles of lipid and glucose metabolism in modulation of β-amyloid, tau, and neurodegeneration in the pathogenesis of Alzheimer diseaseIs neurodegenerative disease a long-latency response to early-life genotoxin exposure?Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of TauProtection of synapses against Alzheimer's-linked toxins: insulin signaling prevents the pathogenic binding of Abeta oligomersThe ε3 and ε4 alleles of human APOE differentially affect tau phosphorylation in hyperinsulinemic and pioglitazone treated miceMetformin attenuates Alzheimer's disease-like neuropathology in obese, leptin-resistant mice.Experimental diabetes mellitus exacerbates tau pathology in a transgenic mouse model of Alzheimer's diseaseUnraveling Alzheimer's: Making Sense of the Relationship between Diabetes and Alzheimer's Disease1Insulin Resistance as a Link between Amyloid-Beta and Tau Pathologies in Alzheimer's Disease.Hyperglycemia induces oxidative stress and impairs axonal transport rates in mice.Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice.The role of tau kinases in Alzheimer's disease.Tau phosphorylation and μ-calpain activation mediate the dexamethasone-induced inhibition on the insulin-stimulated Akt phosphorylation.Increased protein aggregation in Zucker diabetic fatty rat brain: identification of key mechanistic targets and the therapeutic application of hydrogen sulfide.Morin attenuates tau hyperphosphorylation by inhibiting GSK3β.Antiallodynic Effects of Electroacupuncture Combined with MK-801 Treatment through the Regulation of p35/p25 in Experimental Diabetic NeuropathyFlos Puerariae Extract Ameliorates Cognitive Impairment in Streptozotocin-Induced Diabetic Mice.Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer's disease by exendin-4Deregulation of protein phosphatase 2A and hyperphosphorylation of τ protein following onset of diabetes in NOD mice.Increased Spontaneous Central Bleeding and Cognition Impairment in APP/PS1 Mice with Poorly Controlled Diabetes Mellitus.Genome-wide comparative analysis revealed significant transcriptome changes in mice after Toxoplasma gondii infectionBetaine Alleviates Hypertriglycemia and Tau Hyperphosphorylation in db/db Mice.A look inside the diabetic brain: Contributors to diabetes-induced brain aging.Genetic ablation of tau mitigates cognitive impairment induced by type 1 diabetes.Experimental induction of type 2 diabetes in aging-accelerated mice triggered Alzheimer-like pathology and memory deficitsHow does diabetes accelerate Alzheimer disease pathology?Chronic mild cerebrovascular dysfunction as a cause for Alzheimer's disease?Brain insulin dysregulation: implication for neurological and neuropsychiatric disorders.Neurotoxic saboteurs: straws that break the hippo's (hippocampus) back drive cognitive impairment and Alzheimer's Disease.Cellular and metabolic alterations in the hippocampus caused by insulin signalling dysfunction and its association with cognitive impairment during aging and Alzheimer's disease: studies in animal models.Insulin dysfunction and Tau pathology.Brain alterations and clinical symptoms of dementia in diabetes: aβ/tau-dependent and independent mechanisms.Hyperglycemia-induced tau cleavage in vitro and in vivo: a possible link between diabetes and Alzheimer's disease.Adaptive responses to alloxan-induced mild oxidative stress ameliorate certain tauopathy phenotypes.Determination of the Best Concentration of Streptozotocin to Create a Diabetic Brain Using Histological Techniques.High glucose induces formation of tau hyperphosphorylation via Cav-1-mTOR pathway: A potential molecular mechanism for diabetes-induced cognitive dysfunction.Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet.Insulin deficiency exacerbates cerebral amyloidosis and behavioral deficits in an Alzheimer transgenic mouse model.Insulin deprivation induces PP2A inhibition and tau hyperphosphorylation in hTau mice, a model of Alzheimer's disease-like tau pathology.
P2860
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P2860
Tau is hyperphosphorylated at multiple sites in mouse brain in vivo after streptozotocin-induced insulin deficiency
description
2006 nî lūn-bûn
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name
Tau is hyperphosphorylated at ...... cin-induced insulin deficiency
@ast
Tau is hyperphosphorylated at ...... cin-induced insulin deficiency
@en
type
label
Tau is hyperphosphorylated at ...... cin-induced insulin deficiency
@ast
Tau is hyperphosphorylated at ...... cin-induced insulin deficiency
@en
prefLabel
Tau is hyperphosphorylated at ...... cin-induced insulin deficiency
@ast
Tau is hyperphosphorylated at ...... cin-induced insulin deficiency
@en
P2093
P2860
P356
P1433
P1476
Tau is hyperphosphorylated at ...... cin-induced insulin deficiency
@en
P2093
Anna A Zmijewska
Buffie J Clodfelder-Miller
Gail V W Johnson
Richard S Jope
P2860
P304
P356
10.2337/DB06-0485
P407
P577
2006-12-01T00:00:00Z