Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.
about
Inherited predisposition to glioma.Loss of heterozygosity of M6P/IGF2R gene is an early event in the development of prostate cancer.Automated mass action model space generation and analysis methods for two-reactant combinatorially complex equilibriums: an analysis of ATP-induced ribonucleotide reductase R1 hexamerization data.Genomic imprinting: implications for human disease.Imprinted genes as potential genetic and epigenetic toxicologic targetsMSH2 c.1452-1455delAATG is a founder mutation and an important cause of hereditary nonpolyposis colorectal cancer in the southern Chinese population.Microsatellite instability in pediatric high grade glioma is associated with genomic profile and differential target gene inactivation.Distinct clinical features associated with microsatellite instability in colorectal cancers of young patients.Type A microsatellite instability in pediatric gliomas as an indicator of Turcot syndrome.Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: a report from the Children's Oncology Group.Constitutional mismatch repair-deficiency syndrome: have we so far seen only the tip of an iceberg?p53, mdm2, EGFR, and msh2 expression in paired initial and recurrent glioblastoma multiforme.Functional characterization of pathogenic human MSH2 missense mutations in Saccharomyces cerevisiae.Evaluation of microsatellite instability in tumors of central nervous system: A pilot studyHigh-resolution genome-wide allelotype analysis identifies loss of chromosome 14q as a recurrent genetic alteration in astrocytic tumoursGermline truncating mutations in both MSH2 and BRCA2 in a single kindred.Missense mutations of MLH1 and MSH2 genes detected in patients with gastrointestinal cancer are associated with exonic splicing enhancers and silencers.The p38 mitogen-activated protein kinase pathway links the DNA mismatch repair system to the G2 checkpoint and to resistance to chemotherapeutic DNA-methylating agentsGermline, somatic and epigenetic events underlying mismatch repair deficiency in colorectal and HNPCC-related cancers.M6P/IGF2R is mutated in squamous cell carcinoma of the lung.Immune Checkpoint Inhibitors in Gliomas.Mismatch Repair Deficiency and Response to Immune Checkpoint BlockadeTemozolomide induced c-Myc-mediated apoptosis via Akt signalling in MGMT expressing glioblastoma cells.Microsatellite instability, PTEN and p53 germline mutations in glioma families.Establishment and characterization of nine human brain tumor cell lines.Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.Alterations of p53, BCL-2, and hMSH2 protein expression in the normal brain tissues, gliosis, and gliomas.Microsatellite instability and novel mismatch repair gene mutations in northern Chinese population with hereditary non-polyposis colorectal cancer.Genetic changes of MLH1 and MSH2 genes could explain constant findings on microsatellite instability in intracranial meningioma.Microsatellite instability in pediatric and adult high-grade gliomas.Glioblastomas, astrocytomas and oligodendrogliomas linked to Lynch syndrome.Amplification and overexpression of epidermal growth factor receptor gene in glioblastomas of Chinese patients correlates with patient's age but not with tumor's clinicopathological pathway.Chromosomal instability and p53 inactivation are required for genesis of glioblastoma but not for colorectal cancer in patients with germline mismatch repair gene mutation.Analysis of human MutS homolog 2 missense mutations in patients with colorectal cancer.Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas.Microsatellite instability and the PTEN1 gene mutation in a subset of early onset gliomas carrying germline mutation or promoter methylation of the hMLH1 gene.Biallelic germline mutations of mismatch-repair genes: a possible cause for multiple pediatric malignancies
P2860
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P2860
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
1998年论文
@zh
1998年论文
@zh-cn
name
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.
@ast
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.
@en
type
label
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.
@ast
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.
@en
prefLabel
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.
@ast
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas.
@en
P2093
P2860
P1476
Microsatellite instability and mutation of DNA mismatch repair genes in gliomas
@en
P2093
P2860
P304
P356
10.1016/S0002-9440(10)65662-3
P407
P577
1998-10-01T00:00:00Z