Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease
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Is tau ready for admission to the prion club?Pin1 in Alzheimer's disease: multiple substrates, one regulatory mechanism?Tangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing ProblemAlzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits.Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice.Alzheimer disease models and human neuropathology: similarities and differencesProteomics analysis of the neurodegeneration in the brain of tau transgenic mice.Neurofibrillary pathology in transgenic mice overexpressing V717F beta-amyloid precursor protein.Tau filament formation in transgenic mice expressing P301L tau.REVIEW: tau protein pathology in Alzheimer's disease and related disorders.Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies.Transgenic models of tauopathies and synucleinopathies.Tau pathology generated by overexpression of tau.Reprogramming of tau alternative splicing by spliceosome-mediated RNA trans-splicing: implications for tauopathies.Learning and memory deficits upon TAU accumulation in Drosophila mushroom body neurons.Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic miceFrontotemporal dementia and tauopathy.Mouse models of Alzheimer's disease: a quest for plaques and tangles.Neurofibrillary and neurodegenerative pathology in APP-transgenic mice injected with AAV2-mutant TAU: neuroprotective effects of Cerebrolysin.Pronuclear injection for the production of transgenic mice.The role of telomerase protein TERT in Alzheimer's disease and in tau-related pathology in vitro.Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5Filamentous tau in oligodendrocytes and astrocytes of transgenic mice expressing the human tau isoform with the P301L mutation.Expression of human apolipoprotein E4 in neurons causes hyperphosphorylation of protein tau in the brains of transgenic mice.Neurodegenerative tauopathy in the worm.The Microtubule-Associated Protein Tau and Its Relevance for Pancreatic Beta Cells.A decade of tau transgenic animal models and beyond.Knock-out and transgenic mouse models of tauopathies.Tauopathy models and human neuropathology: similarities and differences.Tau aggregation and toxicity in tauopathic neurodegenerative diseases.Misfolded tau protein and disease modifying pathways in transgenic rodent models of human tauopathies.Mediators of tau phosphorylation in the pathogenesis of Alzheimer's disease.Increased 4R tau expression and behavioural changes in a novel MAPT-N296H genomic mouse model of tauopathyVaccination as a therapeutic approach to Alzheimer's disease.The role of tau in Alzheimer's disease and related disorders.Neuronal models for studying tau pathology.Modelling early responses to neurodegenerative mutations in mice.Transgenic mouse models of Alzheimer disease: developing a better model as a tool for therapeutic interventions.Invited review: Animal models of tauopathies and their implications for research/translation into the clinic.Accumulation of vesicle-associated human tau in distal dendrites drives degeneration and tau secretion in an in situ cellular tauopathy model.
P2860
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P2860
Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Transgenic expression of the s ...... e stage of Alzheimer's disease
@ast
Transgenic expression of the s ...... e stage of Alzheimer's disease
@en
type
label
Transgenic expression of the s ...... e stage of Alzheimer's disease
@ast
Transgenic expression of the s ...... e stage of Alzheimer's disease
@en
prefLabel
Transgenic expression of the s ...... e stage of Alzheimer's disease
@ast
Transgenic expression of the s ...... e stage of Alzheimer's disease
@en
P2093
P2860
P1476
Transgenic expression of the s ...... e stage of Alzheimer's disease
@en
P2093
P2860
P304
P356
10.1016/S0002-9440(10)65272-8
P407
P577
1999-01-01T00:00:00Z