Accumulation of vesicle-associated human tau in distal dendrites drives degeneration and tau secretion in an in situ cellular tauopathy model.
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Paired helical filaments from Alzheimer disease brain induce intracellular accumulation of Tau protein in aggresomesHeparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seedsIs tau ready for admission to the prion club?Tangles, Toxicity, and Tau Secretion in AD - New Approaches to a Vexing ProblemPrion-like properties of Tau protein: the importance of extracellular Tau as a therapeutic targetElectrophysiological changes precede morphological changes to frontal cortical pyramidal neurons in the rTg4510 mouse model of progressive tauopathyGlial A30P alpha-synuclein pathology segregates neurogenesis from anxiety-related behavior in conditional transgenic mice.Frequent and symmetric deposition of misfolded tau oligomers within presynaptic and postsynaptic terminals in Alzheimer's disease.Expression of Tau40 induces activation of cultured rat microglial cells.Ectosomes: a new mechanism for non-exosomal secretion of tau protein.Prion-like propagation of protein aggregation and related therapeutic strategies.Selective vulnerability to neurodegenerative disease: the curious case of Prion Protein.Expression and purification of tau protein and its frontotemporal dementia variants using a cleavable histidine tagExosomes, an Unmasked Culprit in Neurodegenerative Diseases.Lysosomal fusion dysfunction as a unifying hypothesis for Alzheimer's disease pathology.Cellular mechanisms of protein aggregate propagationThe intersection of amyloid β and tau in glutamatergic synaptic dysfunction and collapse in Alzheimer's disease.Spreading of tau pathology in Alzheimer's disease by cell-to-cell transmission.Propagation of tau pathology in Alzheimer's disease: identification of novel therapeutic targets.Amyotrophic lateral sclerosis--a model of corticofugal axonal spread.Prions and Protein Assemblies that Convey Biological Information in Health and Disease.Proteins recruited to exosomes by tau overexpression implicate novel cellular mechanisms linking tau secretion with Alzheimer's disease.Physiological release of endogenous tau is stimulated by neuronal activity.Formation and propagation of tau oligomeric seeds.Death or secretion? The demise of a plausible assumption about CSF-tau in Alzheimer Disease?Multiple mechanisms of extracellular tau spreading in a non-transgenic tauopathy model.Discovery and characterization of stable and toxic Tau/phospholipid oligomeric complexes.The Evidence for the Spread and Seeding Capacities of the Mutant Huntingtin Protein in in Vitro Systems and Their Therapeutic Implications.Extracellular Vesicle Biology in Alzheimer's Disease and Related Tauopathy.Improved region of interest selection and colocalization analysis in three-dimensional fluorescence microscopy samples using virtual reality
P2860
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P2860
Accumulation of vesicle-associated human tau in distal dendrites drives degeneration and tau secretion in an in situ cellular tauopathy model.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Accumulation of vesicle-associ ...... situ cellular tauopathy model.
@en
type
label
Accumulation of vesicle-associ ...... situ cellular tauopathy model.
@en
prefLabel
Accumulation of vesicle-associ ...... situ cellular tauopathy model.
@en
P2093
P2860
P356
P1476
Accumulation of vesicle-associ ...... situ cellular tauopathy model.
@en
P2093
Garth F Hall
Sangmook Lee
Wonhee Kim
P2860
P304
P356
10.1155/2012/172837
P577
2012-01-17T00:00:00Z