Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy
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Endothelial-Mesenchymal Transition in Regenerative MedicineEpithelial-to-Mesenchymal Transition in Diabetic Nephropathy: Fact or Fiction?TGF-β/Smad signaling in renal fibrosisRegulation of endothelial cell plasticity by TGF-βSmads as therapeutic targets for chronic kidney diseaseExcessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain.Role of the TGF-β/BMP-7/Smad pathways in renal diseasesCellular mechanisms of tissue fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis.Controlling the receptor for advanced glycation end-products to conquer diabetic vascular complicationsRedox control of p53 in the transcriptional regulation of TGF-β1 target genes through SMAD cooperativity.Glomerular endothelial cell injury and damage precedes that of podocytes in adriamycin-induced nephropathy.Endothelial dysfunction exacerbates renal interstitial fibrosis through enhancing fibroblast Smad3 linker phosphorylation in the mouse obstructed kidney.Glomerular endothelial cell injury and cross talk in diabetic kidney diseaseKnockout of toll-like receptor-2 attenuates both the proinflammatory state of diabetes and incipient diabetic nephropathyRole of endothelial-mesenchymal transition (EndoMT) in the pathogenesis of fibrotic disordersRegulation of RAGE for attenuating progression of diabetic vascular complications.The inflammatory response in myocardial injury, repair, and remodelling.BAMBI elimination enhances alternative TGF-β signaling and glomerular dysfunction in diabetic miceGlucagon-Like Peptide 1 Protects against Hyperglycemic-Induced Endothelial-to-Mesenchymal Transition and Improves Myocardial Dysfunction by Suppressing Poly(ADP-Ribose) Polymerase 1 Activity.Transforming growth factor beta signaling in adult cardiovascular diseases and repair.GQ5 Hinders Renal Fibrosis in Obstructive Nephropathy by Selectively Inhibiting TGF-β-Induced Smad3 PhosphorylationCellular and molecular mechanisms of renal fibrosis.Renal interstitial fibrosis: mechanisms and evaluation.Netrin-1 attenuates the progression of renal dysfunction by blocking endothelial-to-mesenchymal transition in the 5/6 nephrectomy rat model.Increased urinary Smad3 is significantly correlated with glomerular hyperfiltration and a reduced glomerular filtration rate and is a new urinary biomarker for diabetic nephropathy.Endothelial-mesenchymal transition and its contribution to the emergence of stem cell phenotypeEpithelial-mesenchymal transition and mesenchymal-epithelial transition response during differentiation of growth-plate chondrocytes in endochondral ossificationStore-Operated Ca2+ Channels in Mesangial Cells Inhibit Matrix Protein Expression.P311 promotes renal fibrosis via TGFβ1/Smad signaling.High glucose mediates endothelial-to-chondrocyte transition in human aortic endothelial cells.Treatment of renal fibrosis by rebalancing TGF-β/Smad signaling with the combination of asiatic acid and naringenin.Role of Transforming Growth Factor-β1 and Smads Signaling Pathway in Intrauterine Adhesion.Quercetin Inhibits Fibroblast Activation and Kidney Fibrosis Involving the Suppression of Mammalian Target of Rapamycin and β-catenin Signaling.In Pulmonary Arterial Hypertension, Reduced BMPR2 Promotes Endothelial-to-Mesenchymal Transition via HMGA1 and Its Target SlugTGF-β/Smad3 signalling regulates the transition of bone marrow-derived macrophages into myofibroblasts during tissue fibrosisYap1 promotes the survival and self-renewal of breast tumor initiating cells via inhibiting Smad3 signalingCytokine mediated tissue fibrosisBleomycin induces endothelial mesenchymal transition through activation of mTOR pathway: a possible mechanism contributing to the sclerotherapy of venous malformations.Diverse roles of TGF-β/Smads in renal fibrosis and inflammation.Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects.
P2860
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P2860
Blockade of endothelial-mesenchymal transition by a Smad3 inhibitor delays the early development of streptozotocin-induced diabetic nephropathy
description
2010 nî lūn-bûn
@nan
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
2010年论文
@zh
2010年论文
@zh-cn
name
Blockade of endothelial-mesenc ...... n-induced diabetic nephropathy
@ast
Blockade of endothelial-mesenc ...... n-induced diabetic nephropathy
@en
type
label
Blockade of endothelial-mesenc ...... n-induced diabetic nephropathy
@ast
Blockade of endothelial-mesenc ...... n-induced diabetic nephropathy
@en
prefLabel
Blockade of endothelial-mesenc ...... n-induced diabetic nephropathy
@ast
Blockade of endothelial-mesenc ...... n-induced diabetic nephropathy
@en
P2093
P2860
P50
P356
P1433
P1476
Blockade of endothelial-mesenc ...... n-induced diabetic nephropathy
@en
P2093
Georgina Caruana
Hiroshi Yamamoto
Yasuhiko Yamamoto
P2860
P304
P356
10.2337/DB09-1631
P407
P577
2010-08-03T00:00:00Z