Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.
about
Transcriptional corepressor SHP recruits SIRT1 histone deacetylase to inhibit LRH-1 transactivationLiver-specific activities of FGF19 require Klotho betaModulation of retinoic acid receptor-related orphan receptor alpha and gamma activity by 7-oxygenated sterol ligandsBile acids activate fibroblast growth factor 19 signaling in human hepatocytes to inhibit cholesterol 7alpha-hydroxylase gene expressionInvolvement of corepressor complex subunit GPS2 in transcriptional pathways governing human bile acid biosynthesisBile acids inhibit duodenal secretin expression via orphan nuclear receptor small heterodimer partner (SHP)Bile acids: regulation of apoptosis by ursodeoxycholic acidForkhead box transcription factor O1 inhibits cholesterol 7alpha-hydroxylase in human hepatocytes and in high fat diet-fed miceBile acids: regulation of synthesisInterdependence of nutrient metabolism and the circadian clock system: Importance for metabolic healthBile acid metabolism and signalingCross-talk between bile acids and intestinal microbiota in host metabolism and healthCytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.Altered hepatic cholesterol metabolism compensates for disruption of phosphatidylcholine transfer protein in miceSide-chain oxysterols: from cells to membranes to molecules.Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene.Fibroblast growth factor 15 deficiency impairs liver regeneration in mice.Improved Coarse-Grained Modeling of Cholesterol-Containing Lipid BilayersAlterations in xenobiotic metabolism in the long-lived Little mice.Herbal medicine Yinchenhaotang protects against α-naphthylisothiocyanate-induced cholestasis in rats.Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.Retinoic acid represses CYP7A1 expression in human hepatocytes and HepG2 cells by FXR/RXR-dependent and independent mechanisms.Nuclear receptor HNF4α binding sequences are widespread in Alu repeatsBile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitusProtective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signalTimosaponin A3 induces hepatotoxicity in rats through inducing oxidative stress and down-regulating bile acid transporters.HNF4α--role in drug metabolism and potential drug target?Conditional Gata4 deletion in mice induces bile acid absorption in the proximal small intestine.The mechanism of enterohepatic circulation in the formation of gallstone disease.Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4alpha.A chronic high-cholesterol diet paradoxically suppresses hepatic CYP7A1 expression in FVB/NJ miceAtorvastatin induces bile acid-synthetic enzyme Cyp7a1 by suppressing FXR signaling in both liver and intestine in mice.Enhanced placental cholesterol efflux by fetal HDL in Smith-Lemli-Opitz syndrome.25-Hydroxycholesterol increases the availability of cholesterol in phospholipid membranesDiscontinued drugs in 2005: cardiovascular drugs.Tissue-specific function of farnesoid X receptor in liver and intestineImpact of physiological levels of chenodeoxycholic acid supplementation on intestinal and hepatic bile acid and cholesterol metabolism in Cyp7a1-deficient mice.The regulation of alfalfa saponin extract on key genes involved in hepatic cholesterol metabolism in hyperlipidemic ratsArginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partnerLessons from hepatocyte-specific Cyp51 knockout mice: impaired cholesterol synthesis leads to oval cell-driven liver injury.
P2860
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P2860
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.
@ast
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.
@en
type
label
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.
@ast
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.
@en
prefLabel
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.
@ast
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms.
@en
P1476
Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms
@en
P2093
John Y L Chiang
P304
P356
10.1016/J.JHEP.2003.11.006
P50
P577
2004-03-01T00:00:00Z