Possible links between glucose-induced changes in the energy state of pancreatic B cells and insulin release. Unmasking by decreasing a stable pool of adenine nucleotides in mouse islets
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The diabetes-linked transcription factor PAX4 promotes {beta}-cell proliferation and survival in rat and human isletsPurinergic signalling and diabetesThe endoplasmic reticulum is a glucose-modulated high-affinity sink for Ca2+ in mouse pancreatic beta-cellsKir6.2 mutations causing neonatal diabetes provide new insights into Kir6.2-SUR1 interactionsAdenylate kinase 2 links mitochondrial energy metabolism to the induction of the unfolded protein response.Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasisAn extract of Artemisia dracunculus L. stimulates insulin secretion from β cells, activates AMPK and suppresses inflammationMeasurement of the Absolute Magnitude and Time Courses of Mitochondrial Membrane Potential in Primary and Clonal Pancreatic Beta-Cells.AMP-activated protein kinase signaling in metabolic regulation.Insulin Resistance in Human iPS Cells Reduces Mitochondrial Size and Function.Purinergic receptors in the endocrine and exocrine pancreas.A highly energetic process couples calcium influx through L-type calcium channels to insulin secretion in pancreatic beta-cells.Glucose-stimulated insulin secretion correlates with changes in mitochondrial and cytosolic Ca2+ in aequorin-expressing INS-1 cellsProtein phosphatases in pancreatic islets.Continuous monitoring of ATP levels in living insulin secreting cells expressing cytosolic firefly luciferase.The Pancreatic β-Cell: A Bioenergetic Perspective.Neuropathogenic role of adenylate kinase-1 in Aβ-mediated tau phosphorylation via AMPK and GSK3β.Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse isletsSuperoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction.Leucine culture reveals that ATP synthase functions as a fuel sensor in pancreatic beta-cells.Tight links between adenine and guanine nucleotide pools in mouse pancreatic islets: a study with mycophenolic acid.Alterations of insulin secretion from mouse islets treated with sulphonylureas: perturbations of Ca2+ regulation prevail over changes in insulin content.Glucose decreases extracellular adenosine levels in isolated mouse and rat pancreatic islets.Exocytosis of insulin: in vivo maturation of mouse endocrine pancreas.Interplay between cytoplasmic Ca2+ and the ATP/ADP ratio: a feedback control mechanism in mouse pancreatic islets.Stronger control of ATP/ADP by proton leak in pancreatic beta-cells than skeletal muscle mitochondria.Insulin secretion and IP levels in two distant lineages of the genus Mus: comparisons with rat islets.Glucose-induced metabolic oscillations parallel those of Ca(2+) and insulin release in clonal insulin-secreting cells. A multiwell approach to oscillatory cell behavior.Chronic exposure to high leucine impairs glucose-induced insulin release by lowering the ATP-to-ADP ratio.Functional effects of KCNJ11 mutations causing neonatal diabetes: enhanced activation by MgATP.Glucose generates sub-plasma membrane ATP microdomains in single islet beta-cells. Potential role for strategically located mitochondria.
P2860
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P2860
Possible links between glucose-induced changes in the energy state of pancreatic B cells and insulin release. Unmasking by decreasing a stable pool of adenine nucleotides in mouse islets
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Possible links between glucose ...... ne nucleotides in mouse islets
@ast
Possible links between glucose ...... ne nucleotides in mouse islets
@en
type
label
Possible links between glucose ...... ne nucleotides in mouse islets
@ast
Possible links between glucose ...... ne nucleotides in mouse islets
@en
prefLabel
Possible links between glucose ...... ne nucleotides in mouse islets
@ast
Possible links between glucose ...... ne nucleotides in mouse islets
@en
P2093
P2860
P356
P1476
Possible links between glucose ...... ne nucleotides in mouse islets
@en
P2093
P2860
P304
P356
10.1172/JCI118219
P407
P577
1995-10-01T00:00:00Z