Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.
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Cyclic AMP dynamics in the pancreatic β-cellTolbutamide stimulation of pancreatic beta-cells involves both cell recruitment and increase in the individual Ca(2+) responseNADH shuttle system regulates K(ATP) channel-dependent pathway and steps distal to cytosolic Ca(2+) concentration elevation in glucose-induced insulin secretionPulsatile insulin release from pancreatic islets with nonoscillatory elevation of cytoplasmic Ca2+Tissue-dependent loss of phosphofructokinase-M in mice with interrupted activity of the distal promoter: impairment in insulin secretionGlucose stimulation of insulin release in the absence of extracellular Ca2+ and in the absence of any increase in intracellular Ca2+ in rat pancreatic islets.Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic beta-cells.Calcium and glycolysis mediate multiple bursting modes in pancreatic islets.Cell signalling in insulin secretion: the molecular targets of ATP, cAMP and sulfonylurea.Compensatory responses to pyruvate carboxylase suppression in islet beta-cells. Preservation of glucose-stimulated insulin secretion.Activators of PKA and Epac distinctly influence insulin secretion and cytosolic Ca2+ in female mouse islets stimulated by glucose and tolbutamide.Multiple effects and stimulation of insulin secretion by the tyrosine kinase inhibitor genistein in normal mouse islets.Reduced cytochrome C is an essential regulator of sustained insulin secretion by pancreatic isletsDynamics of insulin secretion and the clinical implications for obesity and diabetesContact-induced clustering of syntaxin and munc18 docks secretory granules at the exocytosis site.Identification of a small molecule activator of novel PKCs for promoting glucose-dependent insulin secretion.Hyperinsulinaemic hypoglycaemia in preterm neonates.Evidence of a role for GTP in the potentiation of Ca(2+)-induced insulin secretion by glucose in intact rat islets.Possible links between glucose-induced changes in the energy state of pancreatic B cells and insulin release. Unmasking by decreasing a stable pool of adenine nucleotides in mouse isletsBursting and calcium oscillations in pancreatic beta-cells: specific pacemakers for specific mechanisms.Expression profiling analysis: Uncoupling protein 2 deficiency improves hepatic glucose, lipid profiles and insulin sensitivity in high-fat diet-fed mice by modulating expression of genes in peroxisome proliferator-activated receptor signaling pathwPolyphenol-Rich Extract of Syzygium cumini Leaf Dually Improves Peripheral Insulin Sensitivity and Pancreatic Islet Function in Monosodium L-Glutamate-Induced Obese Rats.Loss of coupling between calcium influx, energy consumption and insulin secretion associated with development of hyperglycaemia in the UCD-T2DM rat model of type 2 diabetes.Reduced peripheral blood mtDNA content is associated with impaired glucose-stimulated islet β cell function in a Chinese population with different degrees of glucose tolerance.Defective insulin secretion and enhanced insulin action in KATP channel-deficient mice.Pancreatic beta-cell signaling: toward better understanding of diabetes and its treatment.Mathematical models for insulin secretion in pancreatic β-cells.Glucagon-like peptide 1-potentiated insulin secretion and proliferation of pancreatic β-cells.Glucose-stimulated insulin secretion: A newer perspective.Reproducible insulin secretion from isolated rat pancreas preparations using an organ bath.The Pancreatic β-Cell: A Bioenergetic Perspective.Activation of the KATP channel-independent signaling pathway by the nonhydrolyzable analog of leucine, BCH.Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse isletsDesensitization of mitochondrial Ca2+ and insulin secretion responses in the beta cell.Transient expression of botulinum neurotoxin C1 light chain differentially inhibits calcium and glucose induced insulin secretion in clonal beta-cells.A Spatial Model of Insulin-Granule Dynamics in Pancreatic β-Cells.Effects of glucose, forskolin and tolbutamide on membrane potential and insulin secretion in the insulin-secreting cell line INS-1.Regulation of CFTR Cl- channel gating by ADP and ATP analogues.Dynamics of Ca2+ and guanosine 5'-[gamma-thio]triphosphate action on insulin secretion from alpha-toxin-permeabilized HIT-T15 cells.Alterations of insulin secretion from mouse islets treated with sulphonylureas: perturbations of Ca2+ regulation prevail over changes in insulin content.
P2860
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P2860
Mechanisms by which glucose can control insulin release independently from its action on adenosine triphosphate-sensitive K+ channels in mouse B cells.
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
Mechanisms by which glucose ca ...... K+ channels in mouse B cells.
@ast
Mechanisms by which glucose ca ...... K+ channels in mouse B cells.
@en
type
label
Mechanisms by which glucose ca ...... K+ channels in mouse B cells.
@ast
Mechanisms by which glucose ca ...... K+ channels in mouse B cells.
@en
prefLabel
Mechanisms by which glucose ca ...... K+ channels in mouse B cells.
@ast
Mechanisms by which glucose ca ...... K+ channels in mouse B cells.
@en
P2093
P2860
P356
P1476
Mechanisms by which glucose ca ...... K+ channels in mouse B cells.
@en
P2093
P2860
P304
P356
10.1172/JCI116308
P407
P577
1993-03-01T00:00:00Z