Human oocytes. Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes.
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Oocyte Maturation and DevelopmentThe zinc spark is an inorganic signature of human egg activationAssembly of Caenorhabditis elegans acentrosomal spindles occurs without evident microtubule-organizing centers and requires microtubule sorting by KLP-18/kinesin-12 and MESP-1Sperm DNA fragmentation index does not correlate with blastocyst aneuploidy or morphological grading.LEGOsĀ® and legacies of centrioles and centrosomes.Erroneous Silencing of the Mitotic Checkpoint by Aberrant Spindle Pole-Kinetochore Coordination.Nucleosome functions in spindle assembly and nuclear envelope formation.Freewheeling sisters cause problems.Sister kinetochore splitting and precocious disintegration of bivalents could explain the maternal age effectUnique geometry of sister kinetochores in human oocytes during meiosis I may explain maternal age-associated increases in chromosomal abnormalities.The GTPase SPAG-1 orchestrates meiotic program by dictating meiotic resumption and cytoskeleton architecture in mouse oocytesMeiotic spindle assembly and chromosome segregation in oocytes.The adverse outcome pathway (AOP) for chemical binding to tubulin in oocytes leading to aneuploid offspring.The Janus soul of centrosomes: a paradoxical role in disease?Mosaicism in Preimplantation Human Embryos: When Chromosomal Abnormalities Are the Norm.Tri-directional anaphases as a novel chromosome segregation defect in human oocytes.Physiological Aspects of Female Fertility: Role of the Environment, Modern Lifestyle, and Genetics.Flexible fitting to cryo-EM density map using ensemble molecular dynamics simulations.Dysmorphic patterns are associated with cytoskeletal alterations in human oocytes.The chromosomal basis of meiotic acentrosomal spindle assembly and function in oocytes.How can zygotes segregate entire parental genomes into distinct blastomeres? The zygote metaphase revisited.The cohesion stabilizer sororin favors DNA repair and chromosome segregation during mouse oocyte meiosis.Precarious maintenance of simple DNA repeats in eukaryotes.Haspin kinase regulates microtubule-organizing center clustering and stability through Aurora kinase C in mouse oocytes.Tripolar mitosis and partitioning of the genome arrests human preimplantation development in vitro.Consequences of Centrosome Dysfunction During Brain Development.Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors.Actin protects mammalian eggs against chromosome segregation errors.Delayed Encounter of Parental Genomes Can Lead to Aneuploidy in Saccharomyces cerevisiae.Human female meiosis revised: new insights into the mechanisms of chromosome segregation and aneuploidies from advanced genomics and time-lapse imaging.Meiotic Divisions: No Place for Gender Equality.Shifting meiotic to mitotic spindle assembly in oocytes disrupts chromosome alignment.Mechanisms of kinetochore-microtubule attachment errors in mammalian oocytes.Meeting the meiotic challenge: Specializations in mammalian oocyte spindle formation.Meiotic spindle formation in mammalian oocytes: Implications for human infertility.N-Acetyl-Cysteine and l-Carnitine Prevent Meiotic Oocyte Damage Induced by Follicular Fluid From Infertile Women With Mild Endometriosis.Acquisition of oocyte competence to develop as an embryo: integrated nuclear and cytoplasmic events.Tripolar chromosome segregation drives the association between maternal genotype at variants spanning PLK4 and aneuploidy in human preimplantation embryos.Chromosome structural anomalies due to aberrant spindle forces exerted at gene editing sites in meiosisWhy human eggs are error-prone
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P2860
Human oocytes. Error-prone chromosome-mediated spindle assembly favors chromosome segregation defects in human oocytes.
description
2015 nĆ® lÅ«n-bĆ»n
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2015幓ć®č«ę
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2015幓č«ę
@yue
2015幓č«ę
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2015幓č«ę
@zh-hk
2015幓č«ę
@zh-mo
2015幓č«ę
@zh-tw
2015幓č®ŗę
@wuu
2015幓č®ŗę
@zh
2015幓č®ŗę
@zh-cn
name
Human oocytes. Error-prone chr ...... tion defects in human oocytes.
@ast
Human oocytes. Error-prone chr ...... tion defects in human oocytes.
@en
type
label
Human oocytes. Error-prone chr ...... tion defects in human oocytes.
@ast
Human oocytes. Error-prone chr ...... tion defects in human oocytes.
@en
prefLabel
Human oocytes. Error-prone chr ...... tion defects in human oocytes.
@ast
Human oocytes. Error-prone chr ...... tion defects in human oocytes.
@en
P2860
P356
P1433
P1476
Human oocytes. Error-prone chr ...... ation defects in human oocytes
@en
P2093
Martyn Blayney
Melina Schuh
P2860
P304
P356
10.1126/SCIENCE.AAA9529
P407
P577
2015-06-01T00:00:00Z