Use of human-derived liver cell lines for the detection of environmental and dietary genotoxicants; current state of knowledge.
about
Critical role of toxicologic pathology in a short-term screen for carcinogenicityDig1 protects against cell death provoked by glyphosate-based herbicides in human liver cell linesToxicity assays in nanodrops combining bioassay and morphometric endpointsCompound cytotoxicity profiling using quantitative high-throughput screening.Defined plant extracts can protect human cells against combined xenobiotic effectsAssessment of compound hepatotoxicity using human plateable cryopreserved hepatocytes in a 1536-well-plate format.Bis(hydroxyphenyl)methane-bisphenol F-metabolism by the HepG2 human hepatoma cell line and cryopreserved human hepatocytes.Cytotoxic Activity of Pyrovalerone Derivatives, an Emerging Group of Psychostimulant Designer Cathinones.Similarities and differences in the expression of drug-metabolizing enzymes between human hepatic cell lines and primary human hepatocytes.Use of conventional and -omics based methods for health claims of dietary antioxidants: a critical overview.RNA-Seq gene expression profiling of HepG2 cells: the influence of experimental factors and comparison with liver tissue.miR-27b synergizes with anticancer drugs via p53 activation and CYP1B1 suppression.Green tea catechin intervention of reactive oxygen species-mediated ERK pathway activation and chronically induced breast cell carcinogenesis.Study of Cytotoxic Effects of Benzonitrile PesticidesEvaluation of geno-toxicity of methyl parathion and chlorpyrifos to human liver carcinoma cell line (HepG2).Development of human cell biosensor system for genotoxicity detection based on DNA damage-induced gene expression.Investigation into the effects of antioxidant-rich extract of Tamarindus indica leaf on antioxidant enzyme activities, oxidative stress and gene expression profiles in HepG2 cellsWhich in vitro models could be best used to study hepatocyte polarity?Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assayAntioxidant and anticancer activity of Artemisia princeps var. orientalis extract in HepG2 and Hep3B hepatocellular carcinoma cells.Zebularine upregulates expression of CYP genes through inhibition of DNMT1 and PKR in HepG2 cells.Comparisons between in vitro whole cell imaging and in vivo zebrafish-based approaches for identifying potential human hepatotoxicants earlier in pharmaceutical development.Genotoxic and chemopreventive assessment of Cynara scolymus L. aqueous extract in a human-derived liver cell line.JWH-133, a Selective Cannabinoid CB₂ Receptor Agonist, Exerts Toxic Effects on Neuroblastoma SH-SY5Y Cells.ML-7 amplifies the quinocetone-induced cell death through akt and MAPK-mediated apoptosis on HepG2 cell line.A New HPLC-MS Method for Measuring Maslinic Acid and Oleanolic Acid in HT29 and HepG2 Human Cancer Cells.High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities.Genotoxic and oxidative stress effects of 2-amino-9H-pyrido[2,3-b]indole in human hepatoma G2 (HepG2) and human lung alveolar epithelial (A549) cells.Human mesenchymal stem cells as a novel platform for simultaneous evaluation of cytotoxicity and genotoxicity of pharmaceuticals.Glyphosate commercial formulation causes cytotoxicity, oxidative effects, and apoptosis on human cells: differences with its active ingredient.Genotoxic effects of the carbamate insecticide Pirimor-50® in Vicia faba root tip meristems and human lymphocyte culture after direct application and treatment with its metabolic extracts.Toxicological profiles of selected synthetic cannabinoids showing high binding affinities to the cannabinoid receptor subtype CB₁.Screening for drug-induced hepatotoxicity in primary mouse hepatocytes using acetaminophen, amiodarone, and cyclosporin a as model compounds: an omics-guided approach.The risky cocktail: what combination effects can we expect between ecstasy and other amphetamines?A transcriptomics-based in vitro assay for predicting chemical genotoxicity in vivo.NIST gold nanoparticle reference materials do not induce oxidative DNA damage.Comparative analysis of phase I and II enzyme activities in 5 hepatic cell lines identifies Huh-7 and HCC-T cells with the highest potential to study drug metabolism.Evaluation of okadaic acid-induced genotoxicity in human cells using the micronucleus test and γH2AX analysis.Genotoxic effects of the cyanobacterial hepatotoxin cylindrospermopsin in the HepG2 cell line.Toxicity profiles of four metals and 17 xenobiotics in the human hepatoma cell line HepG2 and the protozoa Tetrahymena pyriformis--a comparison.
P2860
Q28075960-7B514BF8-C62A-4518-9254-1D6209EABC0EQ28384643-D5360802-C530-4AB5-AD24-AEE912CC3F74Q28469117-C7261902-47C0-4335-9C66-6D740576283BQ33323395-6196BB2B-224E-4C7F-B9A9-7E8B2AB51183Q34025411-266983DF-515E-4D8D-B131-63DC351E32DAQ34067184-8EF065BD-AE0B-4DDC-95A9-85854BC30F82Q34201779-92958D9B-63BE-4AF2-9687-7BE7FD2CD5E9Q34530679-1E32F2C2-3C44-49FA-875C-4F1F927E2808Q34702564-AC8504A9-E3CC-4D13-B35A-39C3BC1E2163Q34781792-A2C7B6A5-82AC-4CBD-A9A5-80CB4F511F6BQ35229198-A587637E-A394-4760-81CA-F8527E7A34A0Q35291824-6792E7B3-B00A-4CA4-94AE-F1CBA06D6A7EQ35747346-73EAFE12-C998-4E00-8EBE-ADF22DA776D3Q35764417-2C21A8FC-6DF2-4C69-9495-23450390D96FQ35897281-2EFABE7F-3083-49A2-9083-4B829E1A0F2AQ36177594-8425D84D-7B79-4755-A09E-72BF374423ECQ36257914-2B73DB3C-A176-4B6D-A1CB-705E17158053Q37189719-CE5DDE07-AA59-4708-9B2A-E1491DE9C13FQ37250890-A8DAD2BD-4091-4809-A800-F0CFA7253FF8Q37309443-B48B58D3-C7CD-48A8-BE93-E6910ECAE4C0Q37598574-694A142C-3C1A-46B7-93D4-78245EFCC661Q37975546-73E1F853-55F4-4DA9-8F64-CEF98DB0741CQ38718466-E36BE898-AF40-4CC2-ABBB-4F76A4D49398Q38796819-2BA01146-C707-499C-89A6-743758AAE32DQ38829588-BAA0FF03-8F4F-428D-A80D-6D8B1180652CQ38835237-4E2CFEB5-45BA-44FE-8E4F-330E94A3D9A5Q38846931-A3F688AF-49B3-492E-861C-CBFA271F1FC1Q38896435-59E90F78-6CD9-40CF-AAAD-6CF4E2C452D1Q38924069-27C9FB9C-0A4E-4E61-A2C9-1A64ABD31870Q39033680-40138C4F-7790-4533-AD0D-F6F6AD2F22F6Q39053467-B0BAF010-A299-4110-99FB-73F55FED5703Q39180994-C26309CF-72C0-453C-8BD9-750FF9FFD8B7Q39212268-FBB5C428-4265-41F3-9143-6ECAD7ECE523Q39273495-D2E51D1E-3A67-4A8A-A2CA-73B1F3A22A08Q39343138-113C25FB-58B2-4BA5-BF65-91820FD2A3EDQ39449119-3B90DE51-2EA3-464E-821B-6A4EF0A87B22Q39511367-9646D8B2-E656-41F4-A334-2F253F2316A5Q39517405-C4D5E845-0927-47BF-AA3D-4BCF3F6015F8Q39537467-A0DE7520-709C-4BF7-9968-F5655D5997BCQ39793422-14DB63BC-57C3-49FE-80FE-DCFC057DC852
P2860
Use of human-derived liver cell lines for the detection of environmental and dietary genotoxicants; current state of knowledge.
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Use of human-derived liver cel ...... s; current state of knowledge.
@ast
Use of human-derived liver cel ...... s; current state of knowledge.
@en
type
label
Use of human-derived liver cel ...... s; current state of knowledge.
@ast
Use of human-derived liver cel ...... s; current state of knowledge.
@en
prefLabel
Use of human-derived liver cel ...... s; current state of knowledge.
@ast
Use of human-derived liver cel ...... s; current state of knowledge.
@en
P2093
P1433
P1476
Use of human-derived liver cel ...... s; current state of knowledge.
@en
P2093
F Darroudi
S Kevekordes
S Knasmüller
V Mersch-Sundermann
P304
P356
10.1016/J.TOX.2004.02.008
P407
P577
2004-05-01T00:00:00Z