The RhoGAP domain of CYK-4 has an essential role in RhoA activation.
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Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesisSingle cell pattern formation and transient cytoskeletal arraysCentralspindlin: at the heart of cytokinesisControl of developmental networks by Rac/Rho small GTPases: How cytoskeletal changes during embryogenesis are orchestratedPlasma Membrane Association but Not Midzone Recruitment of RhoGEF ECT2 Is Essential for CytokinesisNuMA interacts with phosphoinositides and links the mitotic spindle with the plasma membrane.A complex of p190RhoGAP-A and anillin modulates RhoA-GTP and the cytokinetic furrow in human cells.CYK4 inhibits Rac1-dependent PAK1 and ARHGEF7 effector pathways during cytokinesisRhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4.Leukemia-associated RhoGEF (LARG) is a novel RhoGEF in cytokinesis and required for the proper completion of abscission.A conserved RhoGAP limits M phase contractility and coordinates with microtubule asters to confine RhoA during cytokinesisDiscovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP.MgcRacGAP restricts active RhoA at the cytokinetic furrow and both RhoA and Rac1 at cell-cell junctions in epithelial cells.Local RhoA activation induces cytokinetic furrows independent of spindle position and cell cycle stageCYK-4 regulates Rac, but not Rho, during cytokinesis.Rho GTPases as regulators of mitosis and cytokinesis in mammalian cells.Molecular control of animal cell cytokinesis.Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesisGenetic suppression of a phosphomimic myosin II identifies system-level factors that promote myosin II cleavage furrow accumulation.The RhoGAP activity of CYK-4/MgcRacGAP functions non-canonically by promoting RhoA activation during cytokinesis.Furrow constriction in animal cell cytokinesis.Annexin V-induced rat Leydig cell proliferation involves Ect2 via RhoA/ROCK signaling pathway.Cell cycle regulation of Rho signaling pathways.Mid1/anillin and the spatial regulation of cytokinesis in fission yeast.Rho GTPases in animal cell cytokinesis: an occupation by the one percent.Endocytic transport and cytokinesis: from regulation of the cytoskeleton to midbody inheritance.Microtubules and actin crosstalk in cell migration and division.Modular regulation of Rho family GTPases in development.Temporal regulation of epithelium formation mediated by FoxA, MKLP1, MgcRacGAP, and PAR-6.Stuck in the middle: Rac, adhesion, and cytokinesis.A GAP that DividesHigh-resolution temporal analysis reveals a functional timeline for the molecular regulation of cytokinesis.LET-99 functions in the astral furrowing pathway, where it is required for myosin enrichment in the contractile ring.The MgcRacGAP SxIP motif tethers Centralspindlin to microtubule plus ends in Xenopus laevis.Cytokinesis in Metazoa and Fungi.Inducing "cytokinesis" without mitosis in unfertilized Drosophila eggs.MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity.CYK-4 functions independently of its centralspindlin partner ZEN-4 to cellularize oocytes in germline syncytia
P2860
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P2860
The RhoGAP domain of CYK-4 has an essential role in RhoA activation.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
The RhoGAP domain of CYK-4 has an essential role in RhoA activation.
@ast
The RhoGAP domain of CYK-4 has an essential role in RhoA activation.
@en
type
label
The RhoGAP domain of CYK-4 has an essential role in RhoA activation.
@ast
The RhoGAP domain of CYK-4 has an essential role in RhoA activation.
@en
prefLabel
The RhoGAP domain of CYK-4 has an essential role in RhoA activation.
@ast
The RhoGAP domain of CYK-4 has an essential role in RhoA activation.
@en
P2093
P2860
P1433
P1476
The RhoGAP domain of CYK-4 has an essential role in RhoA activation.
@en
P2093
Andy Loria
Katrina M Longhini
Michael Glotzer
P2860
P304
P356
10.1016/J.CUB.2011.12.019
P407
P577
2012-01-05T00:00:00Z