The role of β-arrestin2 in the mechanism of morphine tolerance in the mouse and guinea pig gastrointestinal tract.
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Chronic opioid induced constipation in patients with nonmalignant pain: challenges and opportunitiesSpecific localization of β-Arrestin2 in myenteric plexus of mouse gastrointestinal tractOpioid-induced mitogen-activated protein kinase signaling in rat enteric neurons following chronic morphine treatment.Morphine decreases enteric neuron excitability via inhibition of sodium channels.Morphine dependence in single enteric neurons from the mouse colon requires deletion of β-arrestin2Opioid receptors and associated regulator of G protein signaling are involved in the cathartic colon of rats.Inflammation-induced abnormalities in the subcellular localization and trafficking of the neurokinin 1 receptor in the enteric nervous system.Differences in the characteristics of tolerance to μ-opioid receptor agonists in the colon from wild type and β-arrestin2 knockout miceDistribution and trafficking of the μ-opioid receptor in enteric neurons of the guinea pig.G Protein-Coupled Receptor Trafficking and Signalling in the Enteric Nervous System: The Past, Present and Future.6β-N-heterocyclic substituted naltrexamine derivative NAP as a potential lead to develop peripheral mu opioid receptor selective antagonists.The Impact of Opioid Treatment on Regional Gastrointestinal Transit.Effects of methylnaltrexone on guinea pig gastrointestinal motility.17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-(4'-pyridylcarboxamido)morphinan (NAP) Modulating the Mu Opioid Receptor in a Biased Fashion6β-N-Heterocyclic Substituted Naltrexamine Derivative BNAP: A Peripherally Selective Mixed MOR/KOR Ligand.cPKCγ membrane translocation is involved in herkinorin‑induced neuroprotection against cerebral ischemia/reperfusion injury in mice.Efficacy and ligand bias at the μ-opioid receptor.β-arrestins: regulatory role and therapeutic potential in opioid and cannabinoid receptor-mediated analgesia.Molecular physiology of enteric opioid receptors.Site and mechanism of morphine tolerance in the gastrointestinal tract.Opioidergic effects on enteric and sensory nerves in the lower GI tract: basic mechanisms and clinical implications.Human native kappa opioid receptor functions not predicted by recombinant receptors: Implications for drug designInsights into the Role of Opioid Receptors in the GI Tract: Experimental Evidence and Therapeutic Relevance.New Formulation of Sustained Release Naloxone Can Reverse Opioid Induced Constipation Without Compromising the Desired Opioid Effects.Effects of acute and repeated treatment with the biased mu opioid receptor agonist TRV130 (oliceridine) on measures of antinociception, gastrointestinal function, and abuse liability in rodents.The gut-brain interaction in opioid tolerance.Pharmacogenetics of opiates in clinical practice: the visible tip of the iceberg.Circular muscle contraction in the mice rectum plays a key role in morphine-induced constipation
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P2860
The role of β-arrestin2 in the mechanism of morphine tolerance in the mouse and guinea pig gastrointestinal tract.
description
2011 nî lūn-bûn
@nan
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
2011年论文
@zh
2011年论文
@zh-cn
name
The role of β-arrestin2 in the ...... ea pig gastrointestinal tract.
@ast
The role of β-arrestin2 in the ...... ea pig gastrointestinal tract.
@en
type
label
The role of β-arrestin2 in the ...... ea pig gastrointestinal tract.
@ast
The role of β-arrestin2 in the ...... ea pig gastrointestinal tract.
@en
prefLabel
The role of β-arrestin2 in the ...... ea pig gastrointestinal tract.
@ast
The role of β-arrestin2 in the ...... ea pig gastrointestinal tract.
@en
P2093
P2860
P356
P1476
The role of β-arrestin2 in the ...... ea pig gastrointestinal tract.
@en
P2093
Gracious R Ross
Hamid I Akbarali
Hercules T Maguma
Minho Kang
Tricia H Smith
William L Dewey
P2860
P304
P356
10.1124/JPET.111.186320
P407
P577
2011-11-30T00:00:00Z