Transcription factors in islet development and physiology: role of PDX-1 in beta-cell function.
about
Insulin Promoter Factor 1 variation is associated with type 2 diabetes in African Americans.Pdx-1 links histone H3-Lys-4 methylation to RNA polymerase II elongation during activation of insulin transcriptionIntrauterine Growth Retardation - A Developmental Model of Type 2 Diabetes.Cell-replacement therapy for diabetes: Generating functional insulin-producing tissue from adult human liver cells.Roux-en-Y gastric bypass promotes expression of PDX-1 and regeneration of beta-cells in Goto-Kakizaki rats.Epigenetics and maternal nutrition: nature v. nurture.PDX-1: demonstration of oncogenic properties in pancreatic cancer.The pancreas is altered by in utero androgen exposure: implications for clinical conditions such as polycystic ovary syndrome (PCOS).Chronic exercise increases plasma brain-derived neurotrophic factor levels, pancreatic islet size, and insulin tolerance in a TrkB-dependent mannerDevelopmental origins of adult disease.Pancreatic and duodenal homeobox-1 nuclear localization is regulated by glucose in dispersed rat islets but not in insulin-secreting cell linesParadoxical effect of rapamycin on inflammatory stress-induced insulin resistance in vitro and in vivo.The Phosphorylation of PDX-1 by Protein Kinase CK2 Is Crucial for Its Stability.Role of pancreatic transcription factors in maintenance of mature β-cell function.miRNA-30a-5p-mediated silencing of Beta2/NeuroD expression is an important initial event of glucotoxicity-induced beta cell dysfunction in rodent models.Downstream regulatory element antagonistic modulator regulates islet prodynorphin expression.Interactions between areas I and II direct pdx-1 expression specifically to islet cell types of the mature and developing pancreas.The pancreatic duodenal homeobox-1 protein (Pdx-1) interacts with histone deacetylases Hdac-1 and Hdac-2 on low levels of glucose.Combining a dipeptidyl peptidase-4 inhibitor, alogliptin, with pioglitazone improves glycaemic control, lipid profiles and beta-cell function in db/db mice.Pleiotropic Roles of PDX-1 in the PancreasTAK-875, a GPR40/FFAR1 agonist, in combination with metformin prevents progression of diabetes and β-cell dysfunction in Zucker diabetic fatty rats.Pluripotent stem cells isolated from human amniotic fluid and differentiation into pancreatic beta-cells.Cellular mechanisms underlying failed beta cell regeneration in offspring of protein-restricted pregnant mice.Taurine Increases Insulin Expression in STZ-Treated Rat Islet Cells In Vitro.
P2860
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P2860
Transcription factors in islet development and physiology: role of PDX-1 in beta-cell function.
description
2004 nî lūn-bûn
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2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
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name
Transcription factors in islet ...... f PDX-1 in beta-cell function.
@ast
Transcription factors in islet ...... f PDX-1 in beta-cell function.
@en
type
label
Transcription factors in islet ...... f PDX-1 in beta-cell function.
@ast
Transcription factors in islet ...... f PDX-1 in beta-cell function.
@en
prefLabel
Transcription factors in islet ...... f PDX-1 in beta-cell function.
@ast
Transcription factors in islet ...... f PDX-1 in beta-cell function.
@en
P2860
P356
P1476
Transcription factors in islet ...... f PDX-1 in beta-cell function.
@en
P2093
Danielle Melloul
P2860
P356
10.1196/ANNALS.1294.003
P407
P577
2004-04-01T00:00:00Z