about
P1343
Sumoylation of MEL1S at lysine 568 and its interaction with CtBP facilitates its repressor activity and the blockade of G-CSF-induced myeloid differentiationMutation at the Evi1 locus in Junbo mice causes susceptibility to otitis mediaSulfonation chemistry as a powerful tool for MALDI TOF/TOF de novo sequencing and post-translational modification analysis.Point mutation in AML1 disrupts subnuclear targeting, prevents myeloid differentiation, and effects a transformation-like phenotype.Chimeras taking shape: potential functions of proteins encoded by chimeric RNA transcripts.Novel domain combinations in proteins encoded by chimeric transcriptsBerbamine inhibits proliferation and induces apoptosis of KU812 cells by increasing Smad3 activity.Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defectsEcotopic viral integration site 1 (EVI1) regulates multiple cellular processes important for cancer and is a synergistic partner for FOS protein in invasive tumors.RUNX1-Evi-1 fusion gene inhibited differentiation and apoptosis in myelopoiesis: an in vivo study.The genetics of the myelodysplastic syndromes: classical cytogenetics and recent molecular insights.Molecular cytogenetics as a clinical test for prognostic and predictive biomarkers in newly diagnosed ovarian cancerGain-of-function mutation of GATA-2 in acute myeloid transformation of chronic myeloid leukemiaThe TEL-AML1 leukemia fusion gene dysregulates the TGF-beta pathway in early B lineage progenitor cells.Runx transcription factors in neuronal development.The role of aberrant transcription factor in the progression of chronic myeloid leukemia.Update on genetic and molecular markers associated with myelodysplastic syndromes.Unraveling the genetics of otitis media: from mouse to human and back again.RUNX1 translocations and fusion genes in malignant hemopathies.The role of Smad signaling in hematopoiesis and translational hematology.Bone marrow neoplastic niche in leukemia.Functional features of EVI1 and EVI1Δ324 isoforms of MECOM gene in genome-wide transcription regulation and oncogenicity.Histone deacetylase inhibitors trichostatin A and valproic acid circumvent apoptosis in human leukemic cells expressing the RUNX1 chimera.Antileukemic roles of human phospholipid scramblase 1 gene, evidence from inducible PLSCR1-expressing leukemic cells.In vivo identification of regulators of cell invasion across basement membranes.An unusual case of splenomegaly and increased lactate dehydrogenase heralding acute myeloid leukemia with eosinophilia and RUNX1-MECOM fusion transcripts.RUNX1/EVI1, which blocks myeloid differentiation, inhibits CCAAT-enhancer binding protein alpha function.Reverse transcriptase-polymerase chain reaction based quantification of the combined MDS-EVI1/EVI1 gene in acute myeloid leukemia.
P2860
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P2860
description
2004 nî lūn-bûn
@nan
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
2004年论文
@zh
2004年论文
@zh-cn
name
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
@ast
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
@en
type
label
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
@ast
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
@en
prefLabel
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
@ast
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
@en
P2860
P356
P1433
P1476
Molecular mechanisms of leukemogenesis by AML1/EVI-1.
@en
P2093
Kinuko Mitani
P2860
P2888
P304
P356
10.1038/SJ.ONC.1207777
P407
P4510
P577
2004-05-01T00:00:00Z