Matriptase protects against experimental colitis and promotes intestinal barrier recovery - Wikidata - awgldk - TriplyDB

Matriptase protects against experimental colitis and promotes intestinal barrier recovery

Matriptase protects against experimental colitis and promotes intestinal barrier recovery

http://www.wikidata.org/entity/Q35785774

about

Protease inhibition as new therapeutic strategy for GI diseases Claudins in intestines: Distribution and functional significance in health and diseases Discovery of Pyridyl Bis(oxy)dibenzimidamide Derivatives as Selective Matriptase Inhibitors Inhibition of Matriptase Activity Results in Decreased Intestinal Epithelial Monolayer Integrity In Vitro Matriptase zymogen supports epithelial development, homeostasis and regeneration Divergent Inhibitor Susceptibility among Airway Lumen-Accessible Tryptic Proteases Reinforced Epithelial Barrier Integrity via Matriptase Induction with Sphingosine-1-Phosphate Did Not Result in Disturbances in Physiological Redox Status.Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling.Prostasin is required for matriptase activation in intestinal epithelial cells to regulate closure of the paracellular pathway.Type II transmembrane serine proteases as potential targets for cancer therapy.Matriptase-mediated cleavage of EpCAM destabilizes claudins and dysregulates intestinal epithelial homeostasis.The Transmembrane Serine Protease HAT-like 4 Is Important for Epidermal Barrier Function to Prevent Body Fluid Loss.Pathophysiological roles of proteases in gastrointestinal disease.Signaling pathways induced by serine proteases to increase intestinal epithelial barrier function.The serine protease-mediated increase in intestinal epithelial barrier function is dependent on occludin and requires an intact tight junction.Regulation of Trek1 expression in nasal mucosa with allergic rhinitis by specific immunotherapy.Regulation of intestinal permeability: The role of proteases Design and synthesis of potent, selective inhibitors of matriptase.A Fluorescent-Labeled Phosphono Bisbenzguanidine As an Activity-Based Probe for Matriptase.Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.Altered Prostasin (CAP1/Prss8) Expression Favors Inflammation and Tissue Remodeling in DSS-induced Colitis.Changing the selectivity profile - from substrate analog inhibitors of thrombin and factor Xa to potent matriptase inhibitors.Panax notoginseng Promotes Repair of Colonic Microvascular Injury in Sprague-Dawley Rats with Experimental Colitis.Intestinal regulation of suppression of tumorigenicity 14 (ST14) and serine peptidase inhibitor, Kunitz type -1 (SPINT1) by transcription factor CDX2

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P2860

Matriptase protects against experimental colitis and promotes intestinal barrier recovery

http://www.wikidata.org/entity/Q35785774

description

2011 nî lūn-bûn

@nan

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

2011年论文

@zh

2011年论文

@zh-cn

name

Matriptase protects against experimental colitis and promotes intestinal barrier recovery

@ast

Matriptase protects against experimental colitis and promotes intestinal barrier recovery

@en

type

label

Matriptase protects against experimental colitis and promotes intestinal barrier recovery

@ast

Matriptase protects against experimental colitis and promotes intestinal barrier recovery

@en

prefLabel

Matriptase protects against experimental colitis and promotes intestinal barrier recovery

@ast

Matriptase protects against experimental colitis and promotes intestinal barrier recovery

@en

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Inflammatory Bowel Diseases

P1476

Matriptase protects against experimental colitis and promotes intestinal barrier recovery

@en

P2093

Antoine Désilets

http://www.w3.org/2001/XMLSchema#string

Marguerite S Buzza

http://www.w3.org/2001/XMLSchema#string

Richard Leduc

http://www.w3.org/2001/XMLSchema#string

Sarah Netzel-Arnett

http://www.w3.org/2001/XMLSchema#string

Toni M Antalis

http://www.w3.org/2001/XMLSchema#string

P2860

Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3

Matriptase and HAI-1 are expressed by normal and malignant epithelial cells in vitro and in vivo

Evidence for the occurrence of membrane-type serine protease 1/matriptase on the basolateral sides of enterocytes

Intestinal mucosal barrier function in health and disease

The primary defect in experimental ileitis originates from a nonhematopoietic source.

Inhibition of human matriptase by eglin c variants.

Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA.

Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine

Cytoskeletal regulation of epithelial barrier function during inflammation.

Host-dependent zonulin secretion causes the impairment of the small intestine barrier function after bacterial exposure.

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1303-1314

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scholarly article

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10.1002/IBD.21930

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7

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18

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Terez Shea-Donohue

Thomas H. Bugge

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2011-11-13T00:00:00Z

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51796522

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22081509

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3288858

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