Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA. - Wikidata - awgldk - TriplyDB

Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA.

Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA.

http://www.wikidata.org/entity/Q33518855

about

Understanding and Targeting MET Signaling in Solid Tumors - Are We There Yet?Ockham's razor for the MET-driven invasive growth linking idiopathic pulmonary fibrosis and cancer Reduced prostasin (CAP1/PRSS8) activity eliminates HAI-1 and HAI-2 deficiency-associated developmental defects by preventing matriptase activation Recent Advances in the Genetics of Vocal Learning Matriptase zymogen supports epithelial development, homeostasis and regeneration Type II transmembrane serine protease gene variants associate with breast cancer.Targeting zymogen activation to control the matriptase-prostasin proteolytic cascade.Pericellular proteolysis in cancer c-Met-induced epithelial carcinogenesis is initiated by the serine protease matriptase Matrix-dependent regulation of AKT in Hepsin-overexpressing PC3 prostate cancer cells.Corin in clinical laboratory diagnostics Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival Matriptase protects against experimental colitis and promotes intestinal barrier recovery Suppression of Tumorigenicity-14, encoding matriptase, is a critical suppressor of colitis and colitis-associated colon carcinogenesis ZEB1-responsive genes in non-small cell lung cancer Epigenetic Silencing of SPINT2 Promotes Cancer Cell Motility via HGF-MET Pathway Activation in Melanoma Serum Glycoproteome Profiles for Distinguishing Intestinal Fibrosis from Inflammation in Crohn's Disease.Targeting matriptase in breast cancer abrogates tumour progression via impairment of stromal-epithelial growth factor signalling.The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin.SPINT2 Deregulation in Prostate Carcinoma The autism risk genes MET and PLAUR differentially impact cortical development Type II transmembrane serine proteases as potential targets for cancer therapy.Differential tumorigenic potential and matriptase activation between PDGF B versus PDGF D in prostate cancer.Matriptase regulates c-Met mediated proliferation and invasion in inflammatory breast cancer.Brief overview of selected approaches in targeting pancreatic adenocarcinoma.Mechanisms of hepatocyte growth factor activation in cancer tissues.cMET in NSCLC: Can We Cut off the Head of the Hydra? From the Pathway to the Resistance.Design and Synthesis of Nonpeptide Inhibitors of Hepatocyte Growth Factor Activation.Membrane-bound serine protease inhibitor HAI-1 is required for maintenance of intestinal epithelial integrity.α-Ketobenzothiazole Serine Protease Inhibitors of Aberrant HGF/c-MET and MSP/RON Kinase Pathway Signaling in Cancer.Hepatocyte Growth Factor, a Key Tumor-Promoting Factor in the Tumor Microenvironment.Loss of hepatocyte growth factor activator inhibitor type 1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model Inhibition of pro-HGF activation by SRI31215, a novel approach to block oncogenic HGF/MET signaling.Inhibitors of HGFA, Matriptase, and Hepsin Serine Proteases: A Nonkinase Strategy to Block Cell Signaling in Cancer.MET Receptor Activation Recent Progress and Advances in HGF/MET-Targeted Therapeutic Agents for Cancer Treatment.

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P2860

Pericellular activation of hepatocyte growth factor by the transmembrane serine proteases matriptase and hepsin, but not by the membrane-associated protease uPA.

http://www.wikidata.org/entity/Q33518855

description

2010 nî lūn-bûn

@nan

2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

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2010年论文

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name

Pericellular activation of hep ...... brane-associated protease uPA.

@ast

Pericellular activation of hep ...... brane-associated protease uPA.

@en

Pericellular activation of hep ...... brane-associated protease uPA.

@nl

type

label

Pericellular activation of hep ...... brane-associated protease uPA.

@ast

Pericellular activation of hep ...... brane-associated protease uPA.

@en

Pericellular activation of hep ...... brane-associated protease uPA.

@nl

prefLabel

Pericellular activation of hep ...... brane-associated protease uPA.

@ast

Pericellular activation of hep ...... brane-associated protease uPA.

@en

Pericellular activation of hep ...... brane-associated protease uPA.

@nl

P1433

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P2860

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P921

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P356

P1433

Biochemical Journal

P1476

Pericellular activation of hep ...... brane-associated protease uPA.

@en

P2093

Andrew M Schumacher

http://www.w3.org/2001/XMLSchema#string

Deyi Qiu

http://www.w3.org/2001/XMLSchema#string

Jennifer L Harris

http://www.w3.org/2001/XMLSchema#string

Juliano Alves

http://www.w3.org/2001/XMLSchema#string

Jun Li

http://www.w3.org/2001/XMLSchema#string

Kate A Owen

http://www.w3.org/2001/XMLSchema#string

Lynette M Kilpatrick

http://www.w3.org/2001/XMLSchema#string

Vincent Ellis

http://www.w3.org/2001/XMLSchema#string

P2860

Cellular localization of membrane-type serine protease 1 and identification of protease-activated receptor-2 and single-chain urokinase-type plasminogen activator as substrates

Novel hepatocyte growth factor (HGF) binding domains on fibronectin and vitronectin coordinate a distinct and amplified Met-integrin induced signalling pathway in endothelial cells

Crystal structure of the NK1 fragment of HGF/SF suggests a novel mode for growth factor dimerization and receptor binding

Hepsin activates pro-hepatocyte growth factor and is inhibited by hepatocyte growth factor activator inhibitor-1B (HAI-1B) and HAI-2.

Activation of hepatocyte growth factor and urokinase/plasminogen activator by matriptase, an epithelial membrane serine protease

Met, metastasis, motility and more

Signalling by HGF/SF and Met: the role of heparan sulphate co-receptors

Placental defect and embryonic lethality in mice lacking hepatocyte growth factor/scatter factor

Scatter factor/hepatocyte growth factor is essential for liver development

Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

P304

219-228

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scholarly article

P356

10.1042/BJ20091448

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P407

P433

2

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P478

426

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P577

2010-02-09T00:00:00Z

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P698

20015050

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P921

transmembrane protein