Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis
about
Identification of a novel inhibitor of differentiation-1 (ID-1) binding partner, caveolin-1, and its role in epithelial-mesenchymal transition and resistance to apoptosis in prostate cancer cellsId4 regulates mammary epithelial cell growth and differentiation and is overexpressed in rat mammary gland carcinomasConstitutive expression of the Id-1 promoter in human metastatic breast cancer cells is linked with the loss of NF-1/Rb/HDAC-1 transcription repressor complexEvidence of increased Id-1 expression and its role in cell proliferation in nasopharyngeal carcinoma cellsThe helix-loop-helix inhibitor of differentiation (ID) proteins induce post-mitotic terminally differentiated Sertoli cells to re-enter the cell cycle and proliferateElevated endogenous expression of the dominant negative basic helix-loop-helix protein ID1 correlates with significant centrosome abnormalities in human tumor cells.Id2 promotes tumor cell migration and invasion through transcriptional repression of semaphorin 3FSmall-molecule inhibitors of USP1 target ID1 degradation in leukemic cells.c-Myc is a critical target for c/EBPalpha in granulopoiesis.Role of Id family proteins in growth control.Targeting Id1 reduces proliferation and invasion in aggressive human salivary gland cancer cells.Lactation defect in mice lacking the helix-loop-helix inhibitor Id2Kaposi's sarcoma-associated herpesvirus latency-associated nuclear antigen induces expression of the helix-loop-helix protein Id-1 in human endothelial cells.ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities.Physical and functional interaction between the ID1 and p65 for activation of NF-κBInhibitor of differentiation 1 transcription factor promotes metabolic reprogramming in hepatocellular carcinoma cells.Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a.Id-1 and Id-2 are markers for metastasis and prognosis in oesophageal squamous cell carcinoma.Overexpression of Id-1 is significantly associated with tumour angiogenesis in human pancreas cancers.Id-I stimulates cell proliferation through activation of EGFR in ovarian cancer cellsExpression of the inhibitor of DNA-binding (ID)-1 protein as an angiogenic mediator in tumour advancement of uterine cervical cancers.Id Proteins Contribute to Tumor Development and Metastatic Colonization in a Model of Bladder Carcinogenesis.Id-1 as a molecular target in therapy for breast cancer cell invasion and metastasis.Id-1, Id-2, and Id-3 co-expression correlates with prognosis in stage I and II lung adenocarcinoma patients treated with surgery and adjuvant chemotherapyNestin expression correlates with nerve and retroperitoneal tissue invasion in pancreatic cancer.Bone marrow and peripheral blood expression of ID1 in human gastric carcinoma patients is a bona fide indicator of lymph node and peritoneal metastasis.Overexpression of inhibitor of DNA-binding (ID)-1 protein related to angiogenesis in tumor advancement of ovarian cancers.The Id3/E47 axis mediates cell-cycle control in human pancreatic ducts and adenocarcinoma.Increasing expression of GST-pi MIF, and ID1 genes in chemoresistant prostate cancer cells.Id2 protein is selectively upregulated by UVB in primary, but not in immortalized human keratinocytes and inhibits differentiation.The helix-loop-helix protein ID1 localizes to centrosomes and rapidly induces abnormal centrosome numbers.Id-1 expression promotes cell survival through activation of NF-kappaB signalling pathway in prostate cancer cells.Apigenin inhibits proliferation of ovarian cancer A2780 cells through Id1.Susceptibility of hepatoma-derived cells to histone deacetylase inhibitors is associated with ID2 expression.Id-1 and the p65 subunit of NF-κB promote migration of nasopharyngeal carcinoma cells and are correlated with poor prognosis.Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells.Evidence of a novel antiapoptotic factor: role of inhibitor of differentiation or DNA binding (Id-1) in anticancer drug-induced apoptosis.Id-1 promotes proliferation of p53-deficient esophageal cancer cells.High ID2 protein expression correlates with a favourable prognosis in patients with primary breast cancer and reduces cellular invasiveness of breast cancer cells.Differential expression of multiple genes in association with MADH4/DPC4/SMAD4 inactivation in pancreatic cancer.
P2860
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P2860
Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Id-1 and Id-2 are overexpresse ...... esions in chronic pancreatitis
@ast
Id-1 and Id-2 are overexpresse ...... esions in chronic pancreatitis
@en
type
label
Id-1 and Id-2 are overexpresse ...... esions in chronic pancreatitis
@ast
Id-1 and Id-2 are overexpresse ...... esions in chronic pancreatitis
@en
prefLabel
Id-1 and Id-2 are overexpresse ...... esions in chronic pancreatitis
@ast
Id-1 and Id-2 are overexpresse ...... esions in chronic pancreatitis
@en
P2093
P2860
P1476
Id-1 and Id-2 are overexpresse ...... esions in chronic pancreatitis
@en
P2093
P2860
P304
P356
10.1016/S0002-9440(10)65180-2
P407
P577
1999-09-01T00:00:00Z