Altered centrosome structure is associated with abnormal mitoses in human breast tumors
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Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerRole of CAP350 in centriolar tubule stability and centriole assemblyThe Syk tyrosine kinase suppresses malignant growth of human breast cancer cellsAurora A, centrosome structure, and the centrosome cycleCentrosomal proteins Nde1 and Su48 form a complex regulated by phosphorylationCentrosome amplification drives chromosomal instability in breast tumor development.Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cellsA dual role of cyclin E in cell proliferation and apoptosis may provide a target for cancer therapyCharacterization of Su48, a centrosome protein essential for cell divisionCentrosomal abnormalities, multipolar mitoses, and chromosomal instability in head and neck tumours with dysfunctional telomeresThe TACC domain identifies a family of centrosomal proteins that can interact with microtubulesOverexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosomep16(INK4a) prevents centrosome dysfunction and genomic instability in primary cells.Heading off with the herd: how cancer cells might maneuver supernumerary centrosomes for directional migrationCDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110Clathrin promotes centrosome integrity in early mitosis through stabilization of centrosomal ch-TOGCentrosome hyperamplification and chromosomal damage after exposure to radiation.Numerical and structural centrosome aberrations are an early and stable event in the adenoma-carcinoma sequence of colorectal carcinomas.Induction of centrosome amplification in p53 siRNA-treated human fibroblast cells by radiation exposure.Primary ciliogenesis defects are associated with human astrocytoma/glioblastoma cells.Centrosome Aberration Frequency and Disease Association in B-Acute Lymphoblastic Leukemia.Aurora kinase inhibitors--rising stars in cancer therapeutics?Low molecular weight cyclin E overexpression shortens mitosis, leading to chromosome missegregation and centrosome amplificationSpecific phosphorylation of nucleophosmin on Thr(199) by cyclin-dependent kinase 2-cyclin E and its role in centrosome duplication.Control of centrin stability by Aurora A.A novel role of the aryl hydrocarbon receptor (AhR) in centrosome amplification - implications for chemoprevention.Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells.Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.Primary cilia are decreased in breast cancer: analysis of a collection of human breast cancer cell lines and tissuesDifferential expression of centrosome regulators in Her2+ breast cancer cells versus non-tumorigenic MCF10A cells.The arithmetic of centrosome biogenesis.Antizyme restrains centrosome amplification by regulating the accumulation of Mps1 at centrosomesCan the centrosome be a marker for DNA ploidy in breast cancer?Pin1 regulates centrosome duplication, and its overexpression induces centrosome amplification, chromosome instability, and oncogenesisKrüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damageCentrosome-declustering drugs mediate a two-pronged attack on interphase and mitosis in supercentrosomal cancer cells.Centrosome amplification and the development of cancer.On the role of aurora-A in centrosome function.Mouse embryonic fibroblasts null for the Krüppel-like factor 4 gene are genetically unstable.A clinical overview of centrosome amplification in human cancers.
P2860
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P2860
Altered centrosome structure is associated with abnormal mitoses in human breast tumors
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
1999年论文
@zh
1999年论文
@zh-cn
name
Altered centrosome structure is associated with abnormal mitoses in human breast tumors
@ast
Altered centrosome structure is associated with abnormal mitoses in human breast tumors
@en
type
label
Altered centrosome structure is associated with abnormal mitoses in human breast tumors
@ast
Altered centrosome structure is associated with abnormal mitoses in human breast tumors
@en
prefLabel
Altered centrosome structure is associated with abnormal mitoses in human breast tumors
@ast
Altered centrosome structure is associated with abnormal mitoses in human breast tumors
@en
P2860
P1476
Altered centrosome structure is associated with abnormal mitoses in human breast tumors
@en
P2093
J L Salisbury
W L Lingle
P2860
P304
P356
10.1016/S0002-9440(10)65513-7
P407
P577
1999-12-01T00:00:00Z